3o7i - Revision history

OCA at 10:32, 21 February 2024

2024-02-21T10:32:56Z

← Older revision		Revision as of 10:32, 21 February 2024
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	==Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae==		==Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae==
	<StructureSection load='3o7i' size='340' side='right' caption='[[3o7i]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3o7i' size='340' side='right'caption='[[3o7i]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o7i]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Klep7 Klep7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3O7I FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o7i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_MGH_78578 Klebsiella pneumoniae subsp. pneumoniae MGH 78578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O7I FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3o7h\|3o7h]], [[3o7j\|3o7j]], [[3o7k\|3o7k]]</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">KPN78578_16350, KPN_01665 ([http://www.ncbi.nlm.nih~~.~~gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=272620 KLEP7])~~</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7i OCA], [https://pdbe.org/3o7i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o7i RCSB], [https://www.ebi.ac.uk/pdbsum/3o7i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o7i ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3o7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7i OCA], [~~http~~://pdbe.org/3o7i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3o7i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3o7i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3o7i ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/A6T925_KLEP7 A6T925_KLEP7]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o7i ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o7i ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The stereospecific oxidative degradation of uric acid to (S)-allantoin was recently shown to proceed via three enzymatic steps. The final conversion is a decarboxylation of the unstable intermediate 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) and is catalyzed by OHCU decarboxylase. Here we present the structures of Klebsiella pneumoniae OHCU decarboxylase in unliganded form and with bound allantoin. These structures provide evidence that ligand binding organizes the active site residues for catalysis. Modeling of the substrate and intermediates provides additional support for this hypothesis. In addition we characterize the steady state kinetics of this enzyme and report the first OHCU decarboxylase inhibitor, allopurinol, a structural isomer of hypoxanthine. This molecule is a competitive inhibitor of K. pneumoniae OHCU decarboxylase with a K(i) of 30 +/- 2 mum. Circular dichroism measurements confirm structural observations that this inhibitor disrupts the necessary organization of the active site. Our structural and biochemical studies also provide further insights into the mechanism of catalysis of OHCU decarboxylation.

	Structural and Mechanistic Studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline Decarboxylase.,French JB, Ealick SE J Biol Chem. 2010 Nov 12;285(46):35446-54. Epub 2010 Sep 8. PMID:20826786<ref>PMID:20826786</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 3o7i" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Klep7~~]]		[[Category: Klebsiella pneumoniae subsp. pneumoniae MGH 78578]]
	[[Category: ~~Ealick, S E~~]]		[[Category: Large Structures]]
	[[Category: ~~French, J B~~]]		[[Category: Ealick SE]]
	[[Category: ~~Decarboxylase]]~~		[[Category: French JB]]
	~~[[Category: Lyase~~]]

OCA at 10:02, 30 January 2019

2019-01-30T10:02:30Z

← Older revision		Revision as of 10:02, 30 January 2019
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/3o7i_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/3o7i_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:31, 5 August 2016

2016-08-05T21:31:38Z

← Older revision		Revision as of 21:31, 5 August 2016
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	==Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae==		==Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae==
	<StructureSection load='3o7i' size='340' side='right' caption='[[3o7i]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3o7i' size='340' side='right' caption='[[3o7i]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O7I FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klep7 Klep7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O7I FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o7h\|3o7h]], [[3o7j\|3o7j]], [[3o7k\|3o7k]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o7h\|3o7h]], [[3o7j\|3o7j]], [[3o7k\|3o7k]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KPN78578_16350, KPN_01665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~72407 Klebsiella pneumoniae subsp. pneumoniae~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KPN78578_16350, KPN_01665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272620 KLEP7])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o7i RCSB], [http://www.ebi.ac.uk/pdbsum/3o7i PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7i OCA], [http://pdbe.org/3o7i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o7i RCSB], [http://www.ebi.ac.uk/pdbsum/3o7i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o7i ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o7i ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3o7i" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Klebsiella pneumoniae subsp. pneumoniae~~]]		[[Category: Klep7]]
	[[Category: Ealick, S E]]		[[Category: Ealick, S E]]
	[[Category: French, J B]]		[[Category: French, J B]]
	[[Category: Decarboxylase]]		[[Category: Decarboxylase]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 06:56, 19 December 2014

2014-12-19T06:56:44Z

← Older revision		Revision as of 06:56, 19 December 2014
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	~~{{STRUCTURE_3o7i~~\| ~~PDB~~=3o7i \| ~~SCENE~~= }}		==Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae==
	===~~Crystal~~ structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase ~~from~~ Klebsiella pneumoniae~~===~~		<StructureSection load='3o7i' size='340' side='right' caption='[[3o7i]], [[Resolution\|resolution]] 1.50Å' scene=''>
	~~{{ABSTRACT_PUBMED_20826786}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3o7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O7I FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o7h\|3o7h]], [[3o7j\|3o7j]], [[3o7k\|3o7k]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KPN78578_16350, KPN_01665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=72407 Klebsiella pneumoniae subsp. pneumoniae])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o7i RCSB], [http://www.ebi.ac.uk/pdbsum/3o7i PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/3o7i_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The stereospecific oxidative degradation of uric acid to (S)-allantoin was recently shown to proceed via three enzymatic steps. The final conversion is a decarboxylation of the unstable intermediate 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) and is catalyzed by OHCU decarboxylase. Here we present the structures of Klebsiella pneumoniae OHCU decarboxylase in unliganded form and with bound allantoin. These structures provide evidence that ligand binding organizes the active site residues for catalysis. Modeling of the substrate and intermediates provides additional support for this hypothesis. In addition we characterize the steady state kinetics of this enzyme and report the first OHCU decarboxylase inhibitor, allopurinol, a structural isomer of hypoxanthine. This molecule is a competitive inhibitor of K. pneumoniae OHCU decarboxylase with a K(i) of 30 +/- 2 mum. Circular dichroism measurements confirm structural observations that this inhibitor disrupts the necessary organization of the active site. Our structural and biochemical studies also provide further insights into the mechanism of catalysis of OHCU decarboxylation.

	~~==About this Structure==~~		Structural and Mechanistic Studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline Decarboxylase.,French JB, Ealick SE J Biol Chem. 2010 Nov 12;285(46):35446-54. Epub 2010 Sep 8. PMID:20826786<ref>PMID:20826786</ref>
	~~[[3o7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae~~ Klebsiella pneumoniae ~~subsp~~. ~~pneumoniae]~~. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il/oca-bin~~/~~ocashort?id=3O7I OCA].~~

	==~~Reference~~==		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~<ref group="xtra">PMID:020826786</ref>~~<references ~~group="xtra"~~/><~~references~~/>		</div>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Klebsiella pneumoniae subsp. pneumoniae]]		[[Category: Klebsiella pneumoniae subsp. pneumoniae]]
	[[Category: Ealick, S E.]]		[[Category: Ealick, S E]]
	[[Category: French, J B.]]		[[Category: French, J B]]
	[[Category: Decarboxylase]]		[[Category: Decarboxylase]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA: Protected "3o7i" [edit=sysop:move=sysop]

2013-04-24T12:07:54Z

Protected "3o7i" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:07, 24 April 2013
(No difference)

OCA at 12:07, 24 April 2013

2013-04-24T12:07:53Z

← Older revision		Revision as of 12:07, 24 April 2013
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	~~{{Seed}}~~
	~~[[Image:3o7i.png\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3o7i", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3o7i\| PDB=3o7i \| SCENE= }}		{{STRUCTURE_3o7i\| PDB=3o7i \| SCENE= }}

	===Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae===		===Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_20826786}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 20826786 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_20826786}}		{{ABSTRACT_PUBMED_20826786}}

	==About this Structure==		==About this Structure==
	~~3O7I~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA].		[[3o7i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20826786~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020826786</ref><references group="xtra"/><references/>
	[[Category: Klebsiella pneumoniae subsp. pneumoniae]]		[[Category: Klebsiella pneumoniae subsp. pneumoniae]]
	[[Category: Ealick, S E.]]		[[Category: Ealick, S E.]]
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	[[Category: Decarboxylase]]		[[Category: Decarboxylase]]
	[[Category: Lyase]]		[[Category: Lyase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:45:18 2010''~~

OCA at 10:33, 24 November 2010

2010-11-24T10:33:48Z

← Older revision		Revision as of 10:33, 24 November 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
	[[Image:3o7i.~~jpg~~\|left\|200px]]		[[Image:3o7i.png\|left\|200px]]

	<!--		<!--
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	===Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae===		===Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_20826786}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 20826786 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20826786}}

	==About this Structure==		==About this Structure==
	3O7I is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA].		3O7I is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA].

			==Reference==
			<ref group="xtra">PMID:20826786</ref><references group="xtra"/>
	[[Category: Klebsiella pneumoniae subsp. pneumoniae]]		[[Category: Klebsiella pneumoniae subsp. pneumoniae]]
	[[Category: Ealick, S E.]]		[[Category: Ealick, S E.]]
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	[[Category: Lyase]]		[[Category: Lyase]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri Sep 10 14~~:02:29 2010''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:45:18 2010''

OCA at 09:53, 10 September 2010

2010-09-10T09:53:59Z

← Older revision		Revision as of 09:53, 10 September 2010
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		{{Seed}}
			[[Image:3o7i.jpg\|left\|200px]]

	The ~~entry~~ 3o7i ~~is ON HOLD~~ ~~until Paper Publication~~		<!--
			The line below this paragraph, containing "STRUCTURE_3o7i", creates the "Structure Box" on the page.
			You may change the PDB parameter (which sets the PDB file loaded into the applet)
			or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
			or leave the SCENE parameter empty for the default display.
			-->
			{{STRUCTURE_3o7i\| PDB=3o7i \| SCENE= }}

	~~Authors: French, J.B., Ealick, S.E.~~		===Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae===

	~~Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae~~

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 25 08~~:37:41 2010''		==About this Structure==
			3O7I is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7I OCA].
			[[Category: Klebsiella pneumoniae subsp. pneumoniae]]
			[[Category: Ealick, S E.]]
			[[Category: French, J B.]]
			[[Category: Decarboxylase]]
			[[Category: Lyase]]

			''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 14:02:29 2010''

OCA at 04:29, 25 August 2010

2010-08-25T04:29:50Z

← Older revision		Revision as of 04:29, 25 August 2010
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3o7i is ON HOLD		The entry 3o7i is ON HOLD until Paper Publication

	Authors: French, J.B., Ealick, S.E.		Authors: French, J.B., Ealick, S.E.
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	Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae		Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug ~~11 23~~:38:22 2010''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:37:41 2010''

OCA: New page: '''Unreleased structure''' The entry 3o7i is ON HOLD Authors: French, J.B., Ealick, S.E. Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase f...

2010-08-11T19:31:04Z

New page: '''Unreleased structure''' The entry 3o7i is ON HOLD Authors: French, J.B., Ealick, S.E. Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase f...

New page

'''Unreleased structure'''

The entry 3o7i is ON HOLD

Authors: French, J.B., Ealick, S.E.

Description: Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 23:38:22 2010''