3psy - Revision history

OCA at 17:07, 1 November 2023

2023-11-01T17:07:46Z

← Older revision		Revision as of 17:07, 1 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.43Å</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [https://pdbe.org/3psy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [https://www.ebi.ac.uk/pdbsum/3psy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [https://pdbe.org/3psy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [https://www.ebi.ac.uk/pdbsum/3psy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	~~[[Category: Endothiapepsin]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Heine, A]]		[[Category: Heine A]]
	[[Category: Klebe, G]]		[[Category: Klebe G]]
	[[Category: Koester, H]]		[[Category: Koester H]]
	~~[[Category: Hydrolase]]~~
	~~[[Category: Hydrolase-hydrolase inhibitor complex~~]]

OCA at 08:53, 25 May 2022

2022-05-25T08:53:39Z

← Older revision		Revision as of 08:53, 25 May 2022
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	<StructureSection load='3psy' size='340' side='right'caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>		<StructureSection load='3psy' size='340' side='right'caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PSY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [~~http~~://pdbe.org/3psy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3psy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [https://pdbe.org/3psy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [https://www.ebi.ac.uk/pdbsum/3psy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:33, 11 December 2019

2019-12-11T15:33:38Z

← Older revision		Revision as of 15:33, 11 December 2019
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	==Endothiapepsin in complex with an inhibitor based on the Gewald reaction==		==Endothiapepsin in complex with an inhibitor based on the Gewald reaction==
	<StructureSection load='3psy' size='340' side='right' caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>		<StructureSection load='3psy' size='340' side='right'caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PSY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PSY FirstGlance]. <br>
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [http://pdbe.org/3psy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [http://www.ebi.ac.uk/pdbsum/3psy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [http://pdbe.org/3psy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [http://www.ebi.ac.uk/pdbsum/3psy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Successful lead optimization in structure-based drug discovery depends on the correct deduction and interpretation of the underlying structure-activity relationships (SAR) to facilitate efficient decision-making on the next candidates to be synthesized. Consequently, the question arises, how frequently a binding mode (re)-validation is required, to ensure not to be misled by invalid assumptions on the binding geometry. We present an example in which minor chemical modifications within one inhibitor series lead to surprisingly different binding modes. X-ray structure determination of eight inhibitors derived from one core scaffold resulted in four different binding modes in the aspartic protease endothiapepsin, a well-established surrogate for e.g. renin and beta-secretase. In addition, we suggest an empirical metrics that might serve as an indicator during lead optimization to qualify compounds as candidates for structural revalidation.

			Tracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitors.,Kuhnert M, Koster H, Bartholomaus R, Park AY, Shahim A, Heine A, Steuber H, Klebe G, Diederich WE Angew Chem Int Ed Engl. 2015 Feb 23;54(9):2849-53. doi: 10.1002/anie.201411206., Epub 2015 Jan 28. PMID:25630461<ref>PMID:25630461</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 3psy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Pepsin\|Pepsin]]		*[[Pepsin\|Pepsin]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	[[Category: Endothiapepsin]]		[[Category: Endothiapepsin]]
			[[Category: Large Structures]]
	[[Category: Heine, A]]		[[Category: Heine, A]]
	[[Category: Klebe, G]]		[[Category: Klebe, G]]

OCA at 11:31, 10 December 2016

2016-12-10T11:31:30Z

← Older revision		Revision as of 11:31, 10 December 2016
Line 1:		Line 1:

	==Endothiapepsin in complex with an inhibitor based on the Gewald reaction==		==Endothiapepsin in complex with an inhibitor based on the Gewald reaction==
	<StructureSection load='3psy' size='340' side='right' caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>		<StructureSection load='3psy' size='340' side='right' caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [http://www.ebi.ac.uk/pdbsum/3psy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [http://pdbe.org/3psy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [http://www.ebi.ac.uk/pdbsum/3psy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3psy ProSAT]</span></td></tr>
	</table>		</table>

OCA at 13:48, 9 December 2014

2014-12-09T13:48:04Z

← Older revision		Revision as of 13:48, 9 December 2014
Line 1:		Line 1:
	~~[[Image:3psy.png\|left\|200px]]~~		==Endothiapepsin in complex with an inhibitor based on the Gewald reaction==
			<StructureSection load='3psy' size='340' side='right' caption='[[3psy]], [[Resolution\|resolution]] 1.43Å' scene=''>
	~~{{STRUCTURE_3psy\| PDB=3psy \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3psy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PSY FirstGlance]. <br>
	===Endothiapepsin in complex with an inhibitor based on the Gewald reaction===		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RB9:N-BENZYL-2-({N-[2-(1H-INDOL-3-YL)ETHYL]GLYCYL}AMINO)-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>RB9</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psy RCSB], [http://www.ebi.ac.uk/pdbsum/3psy PDBsum]</span></td></tr>
	==~~About this Structure~~==		</table>
	[[3psy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA].

	==See Also==		==See Also==
	*[[Pepsin\|Pepsin]]		*[[Pepsin\|Pepsin]]
			__TOC__
			</StructureSection>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	[[Category: Endothiapepsin]]		[[Category: Endothiapepsin]]
	[[Category: Heine, A.]]		[[Category: Heine, A]]
	[[Category: Klebe, G.]]		[[Category: Klebe, G]]
	[[Category: Koester, H.]]		[[Category: Koester, H]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 08:29, 20 October 2012

2012-10-20T08:29:21Z

← Older revision		Revision as of 08:29, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
	[[3psy]] is a 1 chain structure ~~of [[Pepsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA].		[[3psy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA].

	==See Also==		==See Also==

OCA at 19:41, 25 July 2012

2012-07-25T19:41:13Z

← Older revision		Revision as of 19:41, 25 July 2012
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		[[Image:3psy.png\|left\|200px]]

	~~The entry~~ 3psy ~~is ON HOLD~~ ~~until Paper Publication~~		{{STRUCTURE_3psy\| PDB=3psy \| SCENE= }}

	~~Authors: Koester, H., Heine, A., Klebe, G.~~		===Endothiapepsin in complex with an inhibitor based on the Gewald reaction===

	~~Description~~: Endothiapepsin in complex ~~with an inhibitor based on the Gewald reaction~~
			==About this Structure==
			[[3psy]] is a 1 chain structure of [[Pepsin]] with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSY OCA].

			==See Also==
			*[[Pepsin\|Pepsin]]
			[[Category: Cryphonectria parasitica]]
			[[Category: Endothiapepsin]]
			[[Category: Heine, A.]]
			[[Category: Klebe, G.]]
			[[Category: Koester, H.]]
			[[Category: Hydrolase]]
			[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA: Protected "3psy" [edit=sysop:move=sysop]

2010-12-29T18:15:19Z

Protected "3psy" [edit=sysop:move=sysop]

← Older revision	Revision as of 18:15, 29 December 2010
(No difference)

OCA at 18:15, 29 December 2010

2010-12-29T18:15:18Z

← Older revision		Revision as of 18:15, 29 December 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3psy is ON HOLD		The entry 3psy is ON HOLD until Paper Publication

	Authors: Koester, H., Heine, A., Klebe, G.		Authors: Koester, H., Heine, A., Klebe, G.

	Description: Endothiapepsin in complex with an inhibitor based on the Gewald reaction		Description: Endothiapepsin in complex with an inhibitor based on the Gewald reaction

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:33:45 2010''~~

OCA: New page: '''Unreleased structure''' The entry 3psy is ON HOLD Authors: Koester, H., Heine, A., Klebe, G. Description: Endothiapepsin in complex with an inhibitor based on the Gewald reaction '...

2010-12-08T08:21:42Z

New page: '''Unreleased structure''' The entry 3psy is ON HOLD Authors: Koester, H., Heine, A., Klebe, G. Description: Endothiapepsin in complex with an inhibitor based on the Gewald reaction '...

New page

'''Unreleased structure'''

The entry 3psy is ON HOLD

Authors: Koester, H., Heine, A., Klebe, G.

Description: Endothiapepsin in complex with an inhibitor based on the Gewald reaction

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