3py2 - Revision history

OCA at 13:35, 1 March 2024

2024-03-01T13:35:17Z

← Older revision		Revision as of 13:35, 1 March 2024
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	<StructureSection load='3py2' size='340' side='right'caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='3py2' size='340' side='right'caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Plafa Plafa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=EDO:1,2~~-~~ETHANEDIOL'>EDO</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.93Å</td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>TPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~5833 PLAFA])</td~~><~~/tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [https://pdbe.org/3py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [https://www.ebi.ac.uk/pdbsum/3py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3py2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [https://pdbe.org/3py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [https://www.ebi.ac.uk/pdbsum/3py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3py2 ProSAT]</span></td></tr>
	</table>		</table>
	~~<div style="background-color:#fffaf0;">~~		== Function ==
	== ~~Publication Abstract from PubMed~~ ==		[https://www.uniprot.org/uniprot/TPIS_PLAFA TPIS_PLAFA]
	Cys 126 is a completely conserved residue in triosephosphate isomerase, which is proximal to the active site, but has been ascribed no specific role in catalysis. A previous study of the C126S and C126A mutants of yeast TIM reported substantial catalytic activity for the mutant enzymes leading to suggest that this residue is implicated in folding and stability [Gonzalez-Mondragon et al, (2004) Biochemistry 43, 3255-3263]. We have re-examined the role of Cys 126 using the Plasmodium falciparum enzyme as a model. Five mutants, C126S, C126A, C126V, C126M and C126T have been characterized. Crystal structures of 3-phosphoglycolate (PGA) bound C126S mutant and the unliganded forms of the C126S and C126A mutants have been determined at a resolution of 1.7 A to 2.1 A. Kinetic studies reveal a approximately 5 fold drop in k(cat) for C126S and C126A mutants, while a approximately 10 fold drop is observed for the other three mutants. At ambient temperature, the wild type enzyme and all five mutants show no concentration dependence of activity. At higher temperatures (> 40 degrees C) the mutant enzymes show a significant concentration dependence, with a dramatic loss in activity below 15 muM. The mutant enzymes also have diminished thermal stability at low concentration as monitored by far UV circular dichroism. These results suggest that Cys 126 contributes to the stability of the dimer interface through a network of interactions involving His 95, Glu 97 and Arg 98, which form direct contacts across the dimer interface. Structured digital abstract: Tim binds to Tim by x-ray crystallography (View interaction).

	Probing the Role of the Fully Conserved Cys 126 Residue in Triosephosphate Isomerase by Site Specific Mutagenesis. Distal Effects on Dimer Stability.,Samanta M, Banerjee M, Murthy MR, Balaram H, Balaram P FEBS J. 2011 Mar 29. doi: ~~10.1111~~/~~j.1742-4658.2011.08110.x. PMID:21447068<ref>PMID:21447068<~~/~~ref>~~

	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~
	</~~div>~~
	~~<div class="pdbe-citations 3py2" style="background-color:#fffaf0;"><~~/~~div>~~

	==See Also==		==See Also==
	*[[Triose phosphate isomerase 3D structures\|Triose phosphate isomerase 3D structures]]		*[[Triose phosphate isomerase 3D structures\|Triose phosphate isomerase 3D structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Plafa]]~~		[[Category: Plasmodium falciparum]]
	~~[[Category: Triose-phosphate isomerase~~]]		[[Category: Balaram H]]
	[[Category: Balaram, H]]		[[Category: Balaram P]]
	[[Category: Balaram, P]]		[[Category: Banerjee M]]
	[[Category: Banerjee, M]]		[[Category: Murthy MRN]]
	[[Category: Murthy~~, M R.N~~]]		[[Category: Samanta M]]
	[[Category: Samanta, M]]
	~~[[Category: Isomerase]]~~
	~~[[Category: Tim barrel~~]]

OCA at 09:01, 25 May 2022

2022-05-25T09:01:24Z

← Older revision		Revision as of 09:01, 25 May 2022
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	==Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase==		==Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase==
	<StructureSection load='3py2' size='340' side='right' caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='3py2' size='340' side='right'caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TPI ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [~~http~~://pdbe.org/3py2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3py2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3py2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [https://pdbe.org/3py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [https://www.ebi.ac.uk/pdbsum/3py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3py2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
	*[[Triose ~~Phosphate Isomerase~~\|Triose ~~Phosphate Isomerase~~]]		*[[Triose phosphate isomerase 3D structures\|Triose phosphate isomerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Plafa]]		[[Category: Plafa]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]

OCA at 14:52, 4 August 2016

2016-08-04T14:52:54Z

← Older revision		Revision as of 14:52, 4 August 2016
Line 1:		Line 1:

	==Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase==		==Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase==
	<StructureSection load='3py2' size='340' side='right' caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='3py2' size='340' side='right' caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Plasmodium_falciparum Plasmodium falciparum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 ~~Plasmodium falciparum~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [http://www.ebi.ac.uk/pdbsum/3py2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [http://pdbe.org/3py2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [http://www.ebi.ac.uk/pdbsum/3py2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3py2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3py2" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Plasmodium falciparum~~]]		[[Category: Plafa]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
	[[Category: Balaram, H]]		[[Category: Balaram, H]]

OCA at 10:27, 19 December 2014

2014-12-19T10:27:17Z

← Older revision		Revision as of 10:27, 19 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_3py2~~\| ~~PDB~~=3py2 \| ~~SCENE~~= }}		==Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase==
	===~~Structure of C126S mutant of~~ Plasmodium falciparum ~~triosephosphate~~ isomerase===		<StructureSection load='3py2' size='340' side='right' caption='[[3py2]], [[Resolution\|resolution]] 1.93Å' scene=''>
	~~{{ABSTRACT_PUBMED_21447068}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3py2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PY2 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3py2 RCSB], [http://www.ebi.ac.uk/pdbsum/3py2 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Cys 126 is a completely conserved residue in triosephosphate isomerase, which is proximal to the active site, but has been ascribed no specific role in catalysis. A previous study of the C126S and C126A mutants of yeast TIM reported substantial catalytic activity for the mutant enzymes leading to suggest that this residue is implicated in folding and stability [Gonzalez-Mondragon et al, (2004) Biochemistry 43, 3255-3263]. We have re-examined the role of Cys 126 using the Plasmodium falciparum enzyme as a model. Five mutants, C126S, C126A, C126V, C126M and C126T have been characterized. Crystal structures of 3-phosphoglycolate (PGA) bound C126S mutant and the unliganded forms of the C126S and C126A mutants have been determined at a resolution of 1.7 A to 2.1 A. Kinetic studies reveal a approximately 5 fold drop in k(cat) for C126S and C126A mutants, while a approximately 10 fold drop is observed for the other three mutants. At ambient temperature, the wild type enzyme and all five mutants show no concentration dependence of activity. At higher temperatures (> 40 degrees C) the mutant enzymes show a significant concentration dependence, with a dramatic loss in activity below 15 muM. The mutant enzymes also have diminished thermal stability at low concentration as monitored by far UV circular dichroism. These results suggest that Cys 126 contributes to the stability of the dimer interface through a network of interactions involving His 95, Glu 97 and Arg 98, which form direct contacts across the dimer interface. Structured digital abstract: Tim binds to Tim by x-ray crystallography (View interaction).

	~~==About this Structure==~~		Probing the Role of the Fully Conserved Cys 126 Residue in Triosephosphate Isomerase by Site Specific Mutagenesis. Distal Effects on Dimer Stability.,Samanta M, Banerjee M, Murthy MR, Balaram H, Balaram P FEBS J. 2011 Mar 29. doi: 10.1111/j.1742-4658.2011.08110.x. PMID:21447068<ref>PMID:21447068</ref>
	~~[[3py2]] is a 2 chain structure with sequence from [http~~:/~~/en~~.~~wikipedia~~.~~org/wiki/Plasmodium_falciparum Plasmodium falciparum]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3PY2 OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]		*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:021447068</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
	[[Category: Balaram, H.]]		[[Category: Balaram, H]]
	[[Category: Balaram, P.]]		[[Category: Balaram, P]]
	[[Category: Banerjee, M.]]		[[Category: Banerjee, M]]
	[[Category: Murthy, M R.N.]]		[[Category: Murthy, M R.N]]
	[[Category: Samanta, M.]]		[[Category: Samanta, M]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Tim barrel]]		[[Category: Tim barrel]]

OCA at 05:37, 28 August 2013

2013-08-28T05:37:12Z

← Older revision		Revision as of 05:37, 28 August 2013
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	==Reference==		==Reference==
	<ref group="xtra">PMID:021447068</ref><references group="xtra"/>		<ref group="xtra">PMID:021447068</ref><references group="xtra"/><references/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]

OCA at 10:21, 11 March 2013

2013-03-11T10:21:45Z

← Older revision		Revision as of 10:21, 11 March 2013
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	~~[[Image:3py2.png\|left\|200px]]~~

	{{STRUCTURE_3py2\| PDB=3py2 \| SCENE= }}		{{STRUCTURE_3py2\| PDB=3py2 \| SCENE= }}

	===Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase===		===Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase===

	{{ABSTRACT_PUBMED_21447068}}		{{ABSTRACT_PUBMED_21447068}}

OCA at 06:57, 20 October 2012

2012-10-20T06:57:21Z

← Older revision		Revision as of 06:57, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[3py2]] is a 2 chain structure ~~of [[Triose Phosphate Isomerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].		[[3py2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].

	==See Also==		==See Also==

OCA at 02:48, 29 August 2012

2012-08-29T02:48:24Z

← Older revision		Revision as of 02:48, 29 August 2012
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	==About this Structure==		==About this Structure==
	[[3py2]] is a 2 chain structure of ~~[[TIM test]] and~~ [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].		[[3py2]] is a 2 chain structure of [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].

	==See Also==		==See Also==
	*[[TIM test\|TIM test]]
	*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]		*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]

OCA at 14:50, 25 July 2012

2012-07-25T14:50:39Z

← Older revision		Revision as of 14:50, 25 July 2012
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	[[Image:3py2.~~jpg~~\|left\|200px]]		[[Image:3py2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3py2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
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	{{STRUCTURE_3py2\| PDB=3py2 \| SCENE= }}		{{STRUCTURE_3py2\| PDB=3py2 \| SCENE= }}

	===Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase===		===Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_21447068}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 21447068 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_21447068}}		{{ABSTRACT_PUBMED_21447068}}

	==About this Structure==		==About this Structure==
	[[3py2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].		[[3py2]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PY2 OCA].

			==See Also==
			*[[TIM test\|TIM test]]
			*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~21447068~~</ref><references group="xtra"/>		<ref group="xtra">PMID:021447068</ref><references group="xtra"/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
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	[[Category: Murthy, M R.N.]]		[[Category: Murthy, M R.N.]]
	[[Category: Samanta, M.]]		[[Category: Samanta, M.]]
			[[Category: Isomerase]]
			[[Category: Tim barrel]]

OCA at 07:12, 27 April 2011

2011-04-27T07:12:30Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:3py2.jpg|left|200px]]
-The entry 3py2 is ON HOLD  until Paper Publication
+<!--
-Authors: Samanta, M., Banerjee, M., Murthy, M.R.N., Balaram, H., Balaram, P.
+===Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase===
-Description: Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase