3rdm - Revision history

OCA at 12:19, 14 March 2024

2024-03-14T12:19:42Z

← Older revision		Revision as of 12:19, 14 March 2024
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	<StructureSection load='3rdm' size='340' side='right'caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3rdm' size='340' side='right'caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_4.1583 As 4.1583~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RDM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RDM FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>~~, ~~<scene name='pdbligand=BTN:BIOTIN'>BTN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [https://pdbe.org/3rdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [https://www.ebi.ac.uk/pdbsum/3rdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [https://pdbe.org/3rdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [https://www.ebi.ac.uk/pdbsum/3rdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).		[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	We have performed a detailed analysis of streptavidin variants with altered specificity towards desthiobiotin. In addition to changes in key residues which widen the ligand binding pocket and accommodate the more structurally flexible desthiobiotin, the data revealed the role of a key, non-active site mutation at the base of the flexible loop (S52G) which slows dissociation of this ligand by approximately sevenfold. Our data suggest that this mutation results in the loss of a stabilizing contact which keeps this loop open and accessible in the absence of ligand. When this mutation was introduced into the wild-type protein, destabilization of the opened loop conferred a approximately 10-fold decrease in both the on-rate and off-rate for the ligand biotin-4-fluoroscein. A similar effect was observed when this mutation was added to a monomeric form of this protein. Our results provide key insight into the role of the streptavidin flexible loop in ligand binding and maintaining high affinity interactions.

	Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.,Magalhaes ML, Czekster CM, Guan R, Malashkevich VN, Almo SC, Levy M Protein Sci. 2011 Jul;20(7):1145-54. doi: 10.1002/pro.642. Epub 2011 May, 12. PMID:21520321<ref>PMID:21520321</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>~~

	==See Also==		==See Also==
	*[[Avidin 3D structures\|Avidin 3D structures]]		*[[Avidin 3D structures\|Avidin 3D structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: As 4 1583]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Almo~~, S C~~]]		[[Category: Streptomyces avidinii]]
	[[Category: Czecster~~, C M~~]]		[[Category: Almo SC]]
	[[Category: Guan, R]]		[[Category: Czecster CM]]
	[[Category: Levy, M]]		[[Category: Guan R]]
	[[Category: Magalhaes, M]]		[[Category: Levy M]]
	[[Category: Malashkevich~~, V N]]~~		[[Category: Magalhaes M]]
	~~[[Category: Biotin binding protein]]~~		[[Category: Malashkevich VN]]
	~~[[Category: Improved desthiobiotin binding]]~~
	~~[[Category: Opened loop destabilization]]~~
	~~[[Category: Streptavidin variant~~]]

OCA at 05:59, 15 June 2022

2022-06-15T05:59:03Z

← Older revision		Revision as of 05:59, 15 June 2022
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	<StructureSection load='3rdm' size='340' side='right'caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3rdm' size='340' side='right'caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3RDM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RDM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [~~http~~://pdbe.org/3rdm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3rdm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [https://pdbe.org/3rdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [https://www.ebi.ac.uk/pdbsum/3rdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).		[[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:39, 25 December 2019

2019-12-25T13:39:48Z

← Older revision		Revision as of 13:39, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of R7-2 streptavidin complexed with biotin/PEG==		==Crystal structure of R7-2 streptavidin complexed with biotin/PEG==
	<StructureSection load='3rdm' size='340' side='right' caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3rdm' size='340' side='right'caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RDM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RDM FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Avidin 3D structures\|Avidin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: As 4 1583]]		[[Category: As 4 1583]]
			[[Category: Large Structures]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Czecster, C M]]		[[Category: Czecster, C M]]

OCA at 19:34, 24 January 2018

2018-01-24T19:34:32Z

← Older revision		Revision as of 19:34, 24 January 2018
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Avidin\|Avidin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:14, 5 August 2016

2016-08-05T21:14:22Z

← Older revision		Revision as of 21:14, 5 August 2016
Line 1:		Line 1:

	==Crystal structure of R7-2 streptavidin complexed with biotin/PEG==		==Crystal structure of R7-2 streptavidin complexed with biotin/PEG==
	<StructureSection load='3rdm' size='340' side='right' caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3rdm' size='340' side='right' caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_avidinii Streptomyces avidinii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RDM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1583 As 4.1583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RDM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [http://www.ebi.ac.uk/pdbsum/3rdm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [http://pdbe.org/3rdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [http://www.ebi.ac.uk/pdbsum/3rdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3rdm" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Streptomyces avidinii~~]]		[[Category: As 4 1583]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Czecster, C M]]		[[Category: Czecster, C M]]

OCA at 05:56, 25 December 2014

2014-12-25T05:56:34Z

← Older revision		Revision as of 05:56, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [http://www.ebi.ac.uk/pdbsum/3rdm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [http://www.ebi.ac.uk/pdbsum/3rdm PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:01, 9 December 2014

2014-12-09T11:01:03Z

← Older revision		Revision as of 11:01, 9 December 2014
Line 1:		Line 1:
	[[~~Image~~:~~3rdm~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of R7-2 streptavidin complexed with biotin/PEG==
			<StructureSection load='3rdm' size='340' side='right' caption='[[3rdm]], [[Resolution\|resolution]] 1.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RDM FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rdo\|3rdo]], [[3rdq\|3rdq]], [[3rds\|3rds]], [[3rdu\|3rdu]], [[3rdx\|3rdx]], [[3re5\|3re5]], [[3re6\|3re6]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rdm RCSB], [http://www.ebi.ac.uk/pdbsum/3rdm PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			We have performed a detailed analysis of streptavidin variants with altered specificity towards desthiobiotin. In addition to changes in key residues which widen the ligand binding pocket and accommodate the more structurally flexible desthiobiotin, the data revealed the role of a key, non-active site mutation at the base of the flexible loop (S52G) which slows dissociation of this ligand by approximately sevenfold. Our data suggest that this mutation results in the loss of a stabilizing contact which keeps this loop open and accessible in the absence of ligand. When this mutation was introduced into the wild-type protein, destabilization of the opened loop conferred a approximately 10-fold decrease in both the on-rate and off-rate for the ligand biotin-4-fluoroscein. A similar effect was observed when this mutation was added to a monomeric form of this protein. Our results provide key insight into the role of the streptavidin flexible loop in ligand binding and maintaining high affinity interactions.

	~~{{STRUCTURE_3rdm\| PDB=3rdm \| SCENE= }}~~		Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding.,Magalhaes ML, Czekster CM, Guan R, Malashkevich VN, Almo SC, Levy M Protein Sci. 2011 Jul;20(7):1145-54. doi: 10.1002/pro.642. Epub 2011 May, 12. PMID:21520321<ref>PMID:21520321</ref>

	~~===Crystal structure of R7-2 streptavidin complexed with biotin~~/~~PEG===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_21520321}}~~

	~~==About this Structure==~~
	~~[[3rdm]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_avidinii Streptomyces avidinii]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=3RDM OCA].~~

	==See Also==		==See Also==
	*[[Avidin\|Avidin]]		*[[Avidin\|Avidin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:021520321<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Streptomyces avidinii]]		[[Category: Streptomyces avidinii]]
	[[Category: Almo, S C.]]		[[Category: Almo, S C]]
	[[Category: Czecster, C M.]]		[[Category: Czecster, C M]]
	[[Category: Guan, R.]]		[[Category: Guan, R]]
	[[Category: Levy, M.]]		[[Category: Levy, M]]
	[[Category: Magalhaes, M.]]		[[Category: Magalhaes, M]]
	[[Category: Malashkevich, V N]]		[[Category: Malashkevich, V N]]
	[[Category: Biotin binding protein]]		[[Category: Biotin binding protein]]

OCA at 13:22, 20 October 2012

2012-10-20T13:22:36Z

← Older revision		Revision as of 13:22, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[3rdm]] is a 1 chain structure ~~of [[Avidin]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA].		[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA].

	==See Also==		==See Also==

OCA at 11:46, 26 July 2012

2012-07-26T11:46:26Z

← Older revision		Revision as of 11:46, 26 July 2012
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	[[Image:3rdm.~~jpg~~\|left\|200px]]		[[Image:3rdm.png\|left\|200px]]

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	{{STRUCTURE_3rdm\| PDB=3rdm \| SCENE= }}		{{STRUCTURE_3rdm\| PDB=3rdm \| SCENE= }}

	===Crystal structure of R7-2 streptavidin complexed with biotin/PEG===		===Crystal structure of R7-2 streptavidin complexed with biotin/PEG===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_21520321}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_21520321}}		{{ABSTRACT_PUBMED_21520321}}

	==About this Structure==		==About this Structure==
	[[3rdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA].		[[3rdm]] is a 1 chain structure of [[Avidin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDM OCA].

			==See Also==
			*[[Avidin\|Avidin]]

	==Reference==		==Reference==

OCA at 18:50, 6 July 2011

2011-07-06T18:50:03Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:3rdm.jpg|left|200px]]
-The entry 3rdm is ON HOLD  until Paper Publication
+<!--
-Authors: Malashkevich, V.N, Magalhaes, M., Czecster, C.M., Guan, R., Levy, M., Almo, S.C.
+===Crystal structure of R7-2 streptavidin complexed with biotin/PEG===
-Description: Crystal structure of R7-2 streptavidin complexed with biotin/PEG