3spl - Revision history

OCA at 17:26, 1 November 2023

2023-11-01T17:26:22Z

← Older revision		Revision as of 17:26, 1 November 2023
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	<StructureSection load='3spl' size='340' side='right'caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3spl' size='340' side='right'caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Fission_yeast Fission yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPL FirstGlance]. <br>		<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPL FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.101Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3sp4\|3sp4]], [[3spd\|3spd]]~~</~~div~~><~~/td~~></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></~~td><td class="sblockDat"~~>~~hnt3, SPCC18.09c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [https://pdbe.org/3spl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [https://www.ebi.ac.uk/pdbsum/3spl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [https://pdbe.org/3spl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [https://www.ebi.ac.uk/pdbsum/3spl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).		[https://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Fission yeast]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Ding, J]]		[[Category: Schizosaccharomyces pombe 972h-]]
	[[Category: Dou, C]]		[[Category: Ding J]]
	[[Category: Gong, Y]]		[[Category: Dou C]]
	[[Category: Jiang, T]]		[[Category: Gong Y]]
	[[Category: Ren, X]]		[[Category: Jiang T]]
	[[Category: Wang, D]]		[[Category: Ren X]]
	[[Category: Zhu, D]]		[[Category: Wang D]]
	~~[[Category: Amp binding]]~~		[[Category: Zhu D]]
	~~[[Category: Dna binding]]~~
	~~[[Category: Dna deadenylase]]~~
	~~[[Category: Hit domain]]~~
	~~[[Category: Hydrolase-dna complex]]~~
	~~[[Category: Zinc finger~~]]

OCA at 08:05, 29 June 2022

2022-06-29T08:05:19Z

← Older revision		Revision as of 08:05, 29 June 2022
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	==Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP==		==Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP==
	<StructureSection load='3spl' size='340' side='right' caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3spl' size='340' side='right'caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3SPL FirstGlance]. <br>		<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sp4\|3sp4]], [[3spd\|3spd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sp4\|3sp4]], [[3spd\|3spd]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hnt3, SPCC18.09c ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hnt3, SPCC18.09c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [~~http~~://pdbe.org/3spl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3spl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3spl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [https://pdbe.org/3spl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [https://www.ebi.ac.uk/pdbsum/3spl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).		[[https://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Fission yeast]]		[[Category: Fission yeast]]
			[[Category: Large Structures]]
	[[Category: Ding, J]]		[[Category: Ding, J]]
	[[Category: Dou, C]]		[[Category: Dou, C]]

OCA at 22:20, 4 August 2016

2016-08-04T22:20:48Z

← Older revision		Revision as of 22:20, 4 August 2016
Line 1:		Line 1:

	==Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP==		==Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP==
	<StructureSection load='3spl' size='340' side='right' caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3spl' size='340' side='right' caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SPL FirstGlance]. <br>		<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SPL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sp4\|3sp4]], [[3spd\|3spd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sp4\|3sp4]], [[3spd\|3spd]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hnt3, SPCC18.09c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 ~~Schizosaccharomyces pombe 972h-~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hnt3, SPCC18.09c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [http://www.ebi.ac.uk/pdbsum/3spl PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [http://pdbe.org/3spl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [http://www.ebi.ac.uk/pdbsum/3spl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3spl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3spl" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Schizosaccharomyces pombe 972h-~~]]		[[Category: Fission yeast]]
	[[Category: Ding, J]]		[[Category: Ding, J]]
	[[Category: Dou, C]]		[[Category: Dou, C]]

OCA at 20:11, 24 December 2014

2014-12-24T20:11:08Z

← Older revision		Revision as of 20:11, 24 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_3spl\| PDB=3spl \| SCENE= }}~~		==Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP==
	===Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP===		<StructureSection load='3spl' size='340' side='right' caption='[[3spl]], [[Resolution\|resolution]] 2.10Å' scene=''>
	~~{{ABSTRACT_PUBMED_21984208}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3spl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SPL FirstGlance]. <br>
	==Function==		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sp4\|3sp4]], [[3spd\|3spd]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hnt3, SPCC18.09c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Schizosaccharomyces pombe 972h-])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3spl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3spl RCSB], [http://www.ebi.ac.uk/pdbsum/3spl PDBsum]</span></td></tr>
			</table>
			== Function ==
	[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).		[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Aprataxin is a DNA deadenylase that resolves DNA 5'-AMP termini and reverses abortive DNA ligation. The crystal structures of Schizosaccharomyces pombe aprataxin Hnt3 in its apo form and in complex to dsDNA and dsDNA-AMP reveal how Hnt3 recognizes and processes 5'-adenylated DNA in a structure-specific manner. The bound DNA adopts a 5'-flap conformation that facilitates 5'-AMP access to the active site, where AMP cleavage occurs by a canonical catalytic mechanism.

	~~==About this Structure==~~		Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA.,Gong Y, Zhu D, Ding J, Dou CN, Ren X, Gu L, Jiang T, Wang DC Nat Struct Mol Biol. 2011 Oct 9;18(11):1297-9. doi: 10.1038/nsmb.2145. PMID:21984208<ref>PMID:21984208</ref>
	~~[[3spl]] is a 8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h~~-]. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il/oca-bin~~/~~ocashort?id=3SPL OCA].~~

	==~~Reference~~==		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~<ref group="xtra">PMID:021984208</ref>~~<references ~~group="xtra"~~/><~~references~~/>		</div>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Schizosaccharomyces pombe 972h-]]		[[Category: Schizosaccharomyces pombe 972h-]]
	[[Category: Ding, J.]]		[[Category: Ding, J]]
	[[Category: Dou, C.]]		[[Category: Dou, C]]
	[[Category: Gong, Y.]]		[[Category: Gong, Y]]
	[[Category: Jiang, T.]]		[[Category: Jiang, T]]
	[[Category: Ren, X.]]		[[Category: Ren, X]]
	[[Category: Wang, D.]]		[[Category: Wang, D]]
	[[Category: Zhu, D.]]		[[Category: Zhu, D]]
	[[Category: Amp binding]]		[[Category: Amp binding]]
	[[Category: Dna binding]]		[[Category: Dna binding]]

OCA at 12:14, 3 July 2013

2013-07-03T12:14:08Z

← Older revision		Revision as of 12:14, 3 July 2013
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	~~[[Image:3spl.png\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3spl", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3spl\| PDB=3spl \| SCENE= }}		{{STRUCTURE_3spl\| PDB=3spl \| SCENE= }}

	===Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP===		===Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP===
			{{ABSTRACT_PUBMED_21984208}}

			==Function==
			[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).

	==About this Structure==		==About this Structure==
	[[3spl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe~~ Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA].		[[3spl]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPL OCA].
	[[Category: Schizosaccharomyces pombe]]
			==Reference==
			<ref group="xtra">PMID:021984208</ref><references group="xtra"/><references/>
			[[Category: Schizosaccharomyces pombe 972h-]]
	[[Category: Ding, J.]]		[[Category: Ding, J.]]
	[[Category: Dou, C.]]		[[Category: Dou, C.]]

OCA at 09:43, 30 October 2011

2011-10-30T09:43:23Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:3spl.png|left|200px]]
-The entry 3spl is ON HOLD  until Paper Publication
+<!--
-Authors: Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
+===Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP===
-Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP

OCA at 08:20, 3 August 2011

2011-08-03T08:20:38Z

← Older revision		Revision as of 08:20, 3 August 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3spl is ON HOLD		The entry 3spl is ON HOLD until Paper Publication

	Authors: Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.		Authors: Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.

	Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP		Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP

OCA at 05:40, 27 July 2011

2011-07-27T05:40:54Z

← Older revision		Revision as of 05:40, 27 July 2011
Line 3:		Line 3:
	The entry 3spl is ON HOLD		The entry 3spl is ON HOLD

	Authors: Gong,Y., Zhu,D., Ding,J., Dou,C., Ren,X., Jiang,T., Wang,D.		Authors: Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.

	Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP		Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP

OCA: Protected "3spl" [edit=sysop:move=sysop]

2011-07-13T06:53:50Z

Protected "3spl" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:53, 13 July 2011
(No difference)

OCA: New page: '''Unreleased structure''' The entry 3spl is ON HOLD Authors: Gong,Y., Zhu,D., Ding,J., Dou,C., Ren,X., Jiang,T., Wang,D. Description: Crystal structure of aprataxin ortholog Hnt3 in c...

2011-07-13T06:53:49Z

New page: '''Unreleased structure''' The entry 3spl is ON HOLD Authors: Gong,Y., Zhu,D., Ding,J., Dou,C., Ren,X., Jiang,T., Wang,D. Description: Crystal structure of aprataxin ortholog Hnt3 in c...

New page

'''Unreleased structure'''

The entry 3spl is ON HOLD

Authors: Gong,Y., Zhu,D., Ding,J., Dou,C., Ren,X., Jiang,T., Wang,D.

Description: Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP