3vsb - Revision history

OCA at 06:49, 9 August 2023

2023-08-09T06:49:40Z

← Older revision		Revision as of 06:49, 9 August 2023
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	==SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX==		==SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX==
	<StructureSection load='3vsb' size='340' side='right' caption='[[3vsb]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3vsb' size='340' side='right'caption='[[3vsb]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3vsb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3vsb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VSB FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=SBD:D-NAPHTHYL-1-ACETAMIDO+BORONIC+ACID+ALANINE'>SBD</scene~~></td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SBD:D-NAPHTHYL-1-ACETAMIDO+BORONIC+ACID+ALANINE'>SBD</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [https://pdbe.org/3vsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [https://www.ebi.ac.uk/pdbsum/3vsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vsb ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [~~http~~://pdbe.org/3vsb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vsb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vsb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/~~SUBT_BACLI SUBT_BACLI]~~] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.		[https://www.uniprot.org/uniprot/SUBC_BACLI SUBC_BACLI] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides (Ref.4, PubMed:11109488). Shows high specificity for aromatic and hydrophobic amino acids in the P1 substrate position (PubMed:11109488). May play an important role in the degradation of feather keratin (PubMed:11109488).<ref>PMID:11109488</ref> <ref>PMID:4967581</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Subtilisin\|Subtilisin]]		*[[Subtilisin 3D structures\|Subtilisin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus licheniformis]]		[[Category: Bacillus licheniformis]]
	[[Category: ~~Subtilisin~~]]		[[Category: Large Structures]]
	[[Category: Eger~~, B T~~]]		[[Category: Eger BT]]
	[[Category: Hynes~~, R C~~]]		[[Category: Hynes RC]]
	[[Category: Jones~~, J B~~]]		[[Category: Jones JB]]
	[[Category: Martichonok, V]]		[[Category: Martichonok V]]
	[[Category: Pai~~, E F~~]]		[[Category: Pai EF]]
	[[Category: Stoll~~, V S]]~~		[[Category: Stoll VS]]
	~~[[Category: Boronic acid inhibitor]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Serine protease~~]]

OCA at 09:14, 21 February 2019

2019-02-21T09:14:47Z

← Older revision		Revision as of 09:14, 21 February 2019
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/3vsb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/3vsb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:42, 5 August 2016

2016-08-05T05:42:17Z

← Older revision		Revision as of 05:42, 5 August 2016
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	==SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX==		==SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX==
	<StructureSection load='3vsb' size='340' side='right' caption='[[3vsb]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3vsb' size='340' side='right' caption='[[3vsb]], [[Resolution\|resolution]] 2.60Å' scene=''>
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	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SBD:D-NAPHTHYL-1-ACETAMIDO+BORONIC+ACID+ALANINE'>SBD</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SBD:D-NAPHTHYL-1-ACETAMIDO+BORONIC+ACID+ALANINE'>SBD</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [http://www.ebi.ac.uk/pdbsum/3vsb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [http://pdbe.org/3vsb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [http://www.ebi.ac.uk/pdbsum/3vsb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vsb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3vsb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3vsb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 16:13, 25 December 2014

2014-12-25T16:13:40Z

← Older revision		Revision as of 16:13, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [http://www.ebi.ac.uk/pdbsum/3vsb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [http://www.ebi.ac.uk/pdbsum/3vsb PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/SUBT_BACLI SUBT_BACLI]] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 15:08, 9 December 2014

2014-12-09T15:08:33Z

← Older revision		Revision as of 15:08, 9 December 2014
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	[[Image:~~3vsb~~.~~png~~\|~~left~~\|~~200px~~]]		==SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX==
			<StructureSection load='3vsb' size='340' side='right' caption='[[3vsb]], [[Resolution\|resolution]] 2.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3vsb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VSB FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SBD:D-NAPHTHYL-1-ACETAMIDO+BORONIC+ACID+ALANINE'>SBD</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vsb RCSB], [http://www.ebi.ac.uk/pdbsum/3vsb PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/3vsb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			In order to probe the structural basis of stereoselectivity in the serine protease family, a series of enantiomeric boronic acids RCH2CH(NHCOCH3)B(OH)2 has been synthesized and kinetically characterized as transition-state analog inhibitors using alpha-chymotrypsin and subtilisin Carlsberg as model systems. When the R-substituent in this series was changed from a p-chlorophenyl to a 1-naphthyl group, alpha-chymotrypsin, but not subtilisin, reversed its usual preference for l-enantiomers and bound more tightly to the D-enantiomer [Martichonok, V., & Jones, J. B. (1996) J. Am. Chem. Soc. 118, 950-958]. The structural factors responsible for the differences in stereoselectivity between the two enzymes have been explored by X-ray crystallographic examination of subtilisin Carlsberg and gamma-chymotrypsin complexes of the L- and D-enantiomers of p-chlorophenyl and 1-naphthyl boronic acid derivatives. In both enzymes, the L-isomers of the inhibitors, which are more closely related to the natural L-amino acid substrates, form tetrahedral adducts, covalently linking the central boron atom and Ogamma of the catalytic serine. The d-isomers, however, differ in the way they interact with subtilisin or gamma-chymotrypsin. With subtilisin, both the D-p-chlorophenyl and D-1-naphthyl inhibitor complexes form covalent Ser Ogamma-to-boron bonds, but with gamma-chymotrypsin, the same inhibitors lead to novel tetrahedral adducts covalently linking both Ser195 Ogamma and His57 Nepsilon2 covalently via the boron atom.

	~~{{STRUCTURE_3vsb\| PDB=3vsb \| SCENE= }}~~		Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.,Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF Biochemistry. 1998 Jan 13;37(2):451-62. PMID:9425066<ref>PMID:9425066</ref>

	~~===SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_9425066}}~~

	~~==About this Structure==~~
	~~[[3vsb]] is~~ a ~~1 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Bacillus_licheniformis Bacillus licheniformis]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=3VSB OCA].~~

	==See Also==		==See Also==
	*[[Subtilisin\|Subtilisin]]		*[[Subtilisin\|Subtilisin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:009425066<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Bacillus licheniformis]]		[[Category: Bacillus licheniformis]]
	[[Category: Subtilisin]]		[[Category: Subtilisin]]
	[[Category: Eger, B T.]]		[[Category: Eger, B T]]
	[[Category: Hynes, R C.]]		[[Category: Hynes, R C]]
	[[Category: Jones, J B.]]		[[Category: Jones, J B]]
	[[Category: Martichonok, V.]]		[[Category: Martichonok, V]]
	[[Category: Pai, E F.]]		[[Category: Pai, E F]]
	[[Category: Stoll, V S.]]		[[Category: Stoll, V S]]
	[[Category: Boronic acid inhibitor]]		[[Category: Boronic acid inhibitor]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serine protease]]		[[Category: Serine protease]]

OCA at 18:46, 20 October 2012

2012-10-20T18:46:19Z

← Older revision		Revision as of 18:46, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[3vsb]] is a 1 chain structure ~~of [[Subtilisin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].		[[3vsb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].

	==See Also==		==See Also==

OCA at 05:10, 27 July 2012

2012-07-27T05:10:25Z

← Older revision		Revision as of 05:10, 27 July 2012
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	[[Image:3vsb.png\|left\|200px]]		[[Image:3vsb.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3vsb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3vsb\| PDB=3vsb \| SCENE= }}		{{STRUCTURE_3vsb\| PDB=3vsb \| SCENE= }}

	===SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX===		===SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_9425066}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 9425066 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_9425066}}		{{ABSTRACT_PUBMED_9425066}}

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	==See Also==		==See Also==
	*[[Subtilisin]]		*[[Subtilisin\|Subtilisin]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~9425066~~</ref><references group="xtra"/>		<ref group="xtra">PMID:009425066</ref><references group="xtra"/>
	[[Category: Bacillus licheniformis]]		[[Category: Bacillus licheniformis]]
	[[Category: Subtilisin]]		[[Category: Subtilisin]]

OCA: Protected "3vsb" [edit=sysop:move=sysop]

2010-12-26T21:19:41Z

Protected "3vsb" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:19, 26 December 2010
(No difference)

OCA at 21:19, 26 December 2010

2010-12-26T21:19:40Z

← Older revision		Revision as of 21:19, 26 December 2010
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	~~{{Seed}}~~
	[[Image:3vsb.png\|left\|200px]]		[[Image:3vsb.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
	~~3VSB~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].		[[3vsb]] is a 1 chain structure of [[Subtilisin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].

			==See Also==
			*[[Subtilisin]]

	==Reference==		==Reference==
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	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serine protease]]		[[Category: Serine protease]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:26:33 2009''~~

OCA at 19:26, 17 February 2009

2009-02-17T19:26:36Z

← Older revision		Revision as of 19:26, 17 February 2009
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	==About this Structure==		==About this Structure==
	3VSB is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].		3VSB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSB OCA].

	==Reference==		==Reference==
	Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes., Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF, Biochemistry. 1998 Jan 13;37(2):451-62. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~9425066 9425066]~~		<ref group="xtra">PMID:9425066</ref><references group="xtra"/>
	[[Category: Bacillus licheniformis]]		[[Category: Bacillus licheniformis]]
	~~[[Category: Single protein]]~~
	[[Category: Subtilisin]]		[[Category: Subtilisin]]
	[[Category: Eger, B T.]]		[[Category: Eger, B T.]]
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	[[Category: Serine protease]]		[[Category: Serine protease]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jul 3 13~~:12:~~04 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:26:33 2009''