3wvb - Revision history

OCA at 13:30, 8 November 2023

2023-11-08T13:30:06Z

← Older revision		Revision as of 13:30, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3wvb' size='340' side='right'caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3wvb' size='340' side='right'caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Metja Metja~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">MJ1251 ([https://www.ncbi.nlm.nih~~.~~gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=243232 METJA])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [https://pdbe.org/3wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [https://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [https://pdbe.org/3wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [https://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Y1251_METJA Y1251_METJA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Metja~~]]		[[Category: Methanocaldococcus jannaschii DSM 2661]]
	[[Category: Ermler, U]]		[[Category: Ermler U]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro T]]
	[[Category: Shima, S]]		[[Category: Shima S]]
	~~[[Category: Hydrolase]]~~
	~~[[Category: Thioesterase~~]]

OCA at 05:32, 10 August 2022

2022-08-10T05:32:45Z

← Older revision		Revision as of 05:32, 10 August 2022
Line 3:		Line 3:
	<StructureSection load='3wvb' size='340' side='right'caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3wvb' size='340' side='right'caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1251 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1251 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [~~http~~://pdbe.org/3wvb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [https://pdbe.org/3wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [https://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:57, 25 December 2019

2019-12-25T09:57:58Z

← Older revision		Revision as of 09:57, 25 December 2019
Line 1:		Line 1:

	==HcgF from Methanocaldococcus jannaschii==		==HcgF from Methanocaldococcus jannaschii==
	<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3wvb' size='340' side='right'caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Metja]]		[[Category: Metja]]
	[[Category: Ermler, U]]		[[Category: Ermler, U]]

OCA at 09:04, 21 February 2019

2019-02-21T09:04:49Z

← Older revision		Revision as of 09:04, 21 February 2019
Line 3:		Line 3:
	<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1251 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [http://pdbe.org/3wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [http://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [http://pdbe.org/3wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [http://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Metja]]
	[[Category: Ermler, U]]		[[Category: Ermler, U]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro, T]]

OCA at 18:40, 1 February 2017

2017-02-01T18:40:21Z

← Older revision		Revision as of 18:40, 1 February 2017
Line 1:		Line 1:

	==HcgF from Methanocaldococcus jannaschii==		==HcgF from Methanocaldococcus jannaschii==
	<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [http://www.ebi.ac.uk/pdbsum/3wvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [http://pdbe.org/3wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [http://www.ebi.ac.uk/pdbsum/3wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3wvb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:31, 30 April 2015

2015-04-30T11:31:44Z

← Older revision		Revision as of 11:31, 30 April 2015
Line 1:		Line 1:
	'''~~Unreleased~~ structure'''		==HcgF from Methanocaldococcus jannaschii==
			<StructureSection load='3wvb' size='340' side='right' caption='[[3wvb]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3wvb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WVB FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wv7\|3wv7]], [[3wv8\|3wv8]], [[3wv9\|3wv9]], [[3wva\|3wva]], [[3wvc\|3wvc]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wvb RCSB], [http://www.ebi.ac.uk/pdbsum/3wvb PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The iron-guanylylpyridinol (FeGP) cofactor of [Fe]-hydrogenase contains a prominent iron centre with an acyl-Fe bond and is the only acyl-organometallic iron compound found in nature. Here, we identify the functions of HcgE and HcgF, involved in the biosynthesis of the FeGP cofactor using structure-to-function strategy. Analysis of the HcgE and HcgF crystal structures with and without bound substrates suggest that HcgE catalyses the adenylylation of the carboxy group of guanylylpyridinol (GP) to afford AMP-GP, and subsequently HcgF catalyses the transesterification of AMP-GP to afford a Cys (HcgF)-S-GP thioester. Both enzymatic reactions are confirmed by in vitro assays. The structural data also offer plausible catalytic mechanisms. This strategy of thioester activation corresponds to that used for ubiquitin activation, a key event in the regulation of multiple cellular processes. It further implicates a nucleophilic attack onto the acyl carbon presumably via an electron-rich Fe(0)- or Fe(I)-carbonyl complex in the Fe-acyl formation.

	~~The entry 3wvb is ON HOLD until Paper Publication~~		Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor.,Fujishiro T, Kahnt J, Ermler U, Shima S Nat Commun. 2015 Apr 17;6:6895. doi: 10.1038/ncomms7895. PMID:25882909<ref>PMID:25882909</ref>

	~~Authors: Fujishiro, T., Ermler~~, U.~~, Shima,~~ S.		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~Description: HcgF from Methanocaldococcus jannaschii~~		== References ==
	~~[[Category: Unreleased Structures]]~~		<references/>
	~~[[Category: Shima, S]]~~		__TOC__
			</StructureSection>
	[[Category: Ermler, U]]		[[Category: Ermler, U]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro, T]]
			[[Category: Shima, S]]
			[[Category: Hydrolase]]
			[[Category: Thioesterase]]

OCA at 12:59, 24 December 2014

2014-12-24T12:59:55Z

← Older revision		Revision as of 12:59, 24 December 2014
Line 6:		Line 6:

	Description: HcgF from Methanocaldococcus jannaschii		Description: HcgF from Methanocaldococcus jannaschii
			[[Category: Unreleased Structures]]
			[[Category: Shima, S]]
			[[Category: Ermler, U]]
			[[Category: Fujishiro, T]]

OCA at 04:48, 4 June 2014

2014-06-04T04:48:30Z

← Older revision		Revision as of 04:48, 4 June 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3wvb is ON HOLD		The entry 3wvb is ON HOLD until Paper Publication

	Authors: Fujishiro, T., Ermler, U., Shima, S.		Authors: Fujishiro, T., Ermler, U., Shima, S.

	Description: HcgF from Methanocaldococcus jannaschii		Description: HcgF from Methanocaldococcus jannaschii

OCA: Protected "3wvb" [edit=sysop:move=sysop]

2014-05-28T07:29:11Z

Protected "3wvb" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:29, 28 May 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 3wvb is ON HOLD Authors: Fujishiro, T., Ermler, U., Shima, S. Description: HcgF from Methanocaldococcus jannaschii

2014-05-28T07:29:09Z

New page: '''Unreleased structure''' The entry 3wvb is ON HOLD Authors: Fujishiro, T., Ermler, U., Shima, S. Description: HcgF from Methanocaldococcus jannaschii

New page

'''Unreleased structure'''

The entry 3wvb is ON HOLD

Authors: Fujishiro, T., Ermler, U., Shima, S.

Description: HcgF from Methanocaldococcus jannaschii