4a8a - Revision history

OCA at 10:47, 9 May 2024

2024-05-09T10:47:53Z

← Older revision		Revision as of 10:47, 9 May 2024
Line 3:		Line 3:
	<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[~~3lyt~~\|~~3lyt~~]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</div></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 14.2Å</td></tr>
	~~<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en~~.~~wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span>~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [https://pdbe.org/4a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [https://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [https://pdbe.org/4a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [https://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI]] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref> [[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[https://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</SX>		</SX>
	[[Category: ~~Ecoli~~]]		[[Category: Escherichia coli K-12]]
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Peptidase Do]]~~		[[Category: Canellas F]]
	[[Category: Canellas, F]]		[[Category: Clausen T]]
	[[Category: Clausen, T]]		[[Category: Ehrmann M]]
	[[Category: Ehrmann, M]]		[[Category: Malet H]]
	[[Category: Malet, H]]		[[Category: Saibil HR]]
	[[Category: Saibil~~, H R~~]]		[[Category: Sawa J]]
	[[Category: Sawa, J]]		[[Category: Thalassinos K]]
	[[Category: Thalassinos, K]]		[[Category: Yan J]]
	[[Category: Yan, J]]
	~~[[Category: Chaperone]]~~
	~~[[Category: Hydrolase-hydrolase complex~~]]

OCA at 05:28, 25 August 2022

2022-08-25T05:28:04Z

← Older revision		Revision as of 05:28, 25 August 2022
Line 3:		Line 3:
	<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli] and [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</div></td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [~~http~~://pdbe.org/4a8a PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [https://pdbe.org/4a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [https://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI]] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref> [[~~http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[[https://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI]] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref> [[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 05:08, 19 November 2020

2020-11-19T05:08:13Z

← Older revision		Revision as of 05:08, 19 November 2020
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://pdbe.org/4a8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://pdbe.org/4a8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>

OCA at 18:47, 10 April 2020

2020-04-10T18:47:30Z

← Older revision		Revision as of 18:47, 10 April 2020
Line 3:		Line 3:
	<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://pdbe.org/4a8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://pdbe.org/4a8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:46, 6 March 2020

2020-03-06T17:46:52Z

← Older revision		Revision as of 17:46, 6 March 2020
Line 1:		Line 1:

	==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==		==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==
	<~~StructureSection~~ load='4a8a' size='340' side='right'caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<SX load='4a8a' size='340' side='right' viewer='molstar' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
Line 25:		Line 25:
	<references/>		<references/>
	__TOC__		__TOC__
	</~~StructureSection~~>		</SX>
	[[Category: Ecoli]]		[[Category: Ecoli]]
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]

OCA at 16:50, 28 August 2019

2019-08-28T16:50:08Z

← Older revision		Revision as of 16:50, 28 August 2019
Line 1:		Line 1:

	==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==		==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==
	<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<StructureSection load='4a8a' size='340' side='right'caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
Line 28:		Line 28:
	[[Category: Ecoli]]		[[Category: Ecoli]]
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
			[[Category: Large Structures]]
	[[Category: Peptidase Do]]		[[Category: Peptidase Do]]
	[[Category: Canellas, F]]		[[Category: Canellas, F]]

OCA at 22:12, 15 November 2017

2017-11-15T22:12:36Z

← Older revision		Revision as of 22:12, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Chick Chick~~] and [http://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Chick]]~~
	[[Category: Ecoli]]		[[Category: Ecoli]]
			[[Category: Gallus gallus]]
	[[Category: Peptidase Do]]		[[Category: Peptidase Do]]
	[[Category: Canellas, F]]		[[Category: Canellas, F]]

OCA at 02:14, 5 August 2016

2016-08-05T02:14:46Z

← Older revision		Revision as of 02:14, 5 August 2016
Line 1:		Line 1:

	==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==		==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==
	<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>		<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~] and [http://en.wikipedia.org/wiki/~~Gallus_gallus Gallus gallus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Hydrolase Hydrolase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_Do Peptidase Do], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://pdbe.org/4a8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8a ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4a8a" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia coli~~]]		[[Category: Chick]]
	[[Category: ~~Gallus gallus~~]]		[[Category: Ecoli]]
	[[Category: ~~Hydrolase~~]]		[[Category: Peptidase Do]]
	[[Category: Canellas, F]]		[[Category: Canellas, F]]
	[[Category: Clausen, T]]		[[Category: Clausen, T]]

OCA at 15:00, 25 December 2014

2014-12-25T15:00:42Z

← Older revision		Revision as of 15:00, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/DEGQ_ECOLI DEGQ_ECOLI]] DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids. Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins. DegQ can substitute for the periplasmic protease DegP.<ref>PMID:8576051</ref> <ref>PMID:8830688</ref> [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:38, 9 December 2014

2014-12-09T17:38:30Z

← Older revision		Revision as of 17:38, 9 December 2014
Line 1:		Line 1:
	[[~~Image~~:~~4a8a~~.~~png~~\|~~left~~\|~~200px~~]]		==Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme==
			<StructureSection load='4a8a' size='340' side='right' caption='[[4a8a]], [[Resolution\|resolution]] 14.20Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4a8a]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8A FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kxx\|1kxx]], [[2ybi\|2ybi]], [[1t6v\|1t6v]], [[1vds\|1vds]], [[1kir\|1kir]], [[1yil\|1yil]], [[1heo\|1heo]], [[1ior\|1ior]], [[1ljg\|1ljg]], [[1jis\|1jis]], [[2w1m\|2w1m]], [[1uic\|1uic]], [[1ykz\|1ykz]], [[1xgq\|1xgq]], [[2war\|2war]], [[1lj3\|1lj3]], [[1dpw\|1dpw]], [[8lyz\|8lyz]], [[2lyo\|2lyo]], [[1g7h\|1g7h]], [[1lks\|1lks]], [[5lyt\|5lyt]], [[1sfb\|1sfb]], [[1ir7\|1ir7]], [[1xei\|1xei]], [[1hel\|1hel]], [[1ljf\|1ljf]], [[1f10\|1f10]], [[1ljk\|1ljk]], [[6lyt\|6lyt]], [[1zmy\|1zmy]], [[2d91\|2d91]], [[2xth\|2xth]], [[1lze\|1lze]], [[1aki\|1aki]], [[1yik\|1yik]], [[2d6b\|2d6b]], [[1lpi\|1lpi]], [[1ndg\|1ndg]], [[1flw\|1flw]], [[4lyt\|4lyt]], [[1jit\|1jit]], [[1lzn\|1lzn]], [[1ja2\|1ja2]], [[1wtn\|1wtn]], [[2fbb\|2fbb]], [[2lym\|2lym]], [[1lz9\|1lz9]], [[1lse\|1lse]], [[1lsm\|1lsm]], [[3lym\|3lym]], [[7lyz\|7lyz]], [[1t3p\|1t3p]], [[2bly\|2bly]], [[1b0d\|1b0d]], [[1her\|1her]], [[1ioq\|1ioq]], [[1nby\|1nby]], [[1qio\|1qio]], [[1xgp\|1xgp]], [[1ps5\|1ps5]], [[1gwd\|1gwd]], [[1v7t\|1v7t]], [[1h6m\|1h6m]], [[1dqj\|1dqj]], [[2a7d\|2a7d]], [[1z55\|1z55]], [[2c8p\|2c8p]], [[1lsb\|1lsb]], [[1flq\|1flq]], [[1jj1\|1jj1]], [[2ybl\|2ybl]], [[1yqv\|1yqv]], [[1hsx\|1hsx]], [[2cds\|2cds]], [[1hf4\|1hf4]], [[1uib\|1uib]], [[1ir9\|1ir9]], [[1rjc\|1rjc]], [[1ic4\|1ic4]], [[1ljh\|1ljh]], [[1xej\|1xej]], [[1ja7\|1ja7]], [[1mel\|1mel]], [[1ri8\|1ri8]], [[1c10\|1c10]], [[1lyo\|1lyo]], [[2xjw\|2xjw]], [[1n4f\|1n4f]], [[2w1y\|2w1y]], [[1g7m\|1g7m]], [[1sf7\|1sf7]], [[1lsf\|1lsf]], [[1fn5\|1fn5]], [[2d4j\|2d4j]], [[1c08\|1c08]], [[3lyz\|3lyz]], [[1bvk\|1bvk]], [[1uif\|1uif]], [[1vau\|1vau]], [[1lma\|1lma]], [[1hc0\|1hc0]], [[1a2y\|1a2y]], [[4lzt\|4lzt]], [[1gxv\|1gxv]], [[1p2c\|1p2c]], [[1ic5\|1ic5]], [[1ua6\|1ua6]], [[1at5\|1at5]], [[1vfb\|1vfb]], [[1vat\|1vat]], [[1lj4\|1lj4]], [[1ja4\|1ja4]], [[4lym\|4lym]], [[1flu\|1flu]], [[1bwh\|1bwh]], [[2hfm\|2hfm]], [[1io5\|1io5]], [[2bpu\|2bpu]], [[1lzb\|1lzb]], [[1lsc\|1lsc]], [[1w6z\|1w6z]], [[2ybn\|2ybn]], [[3lyo\|3lyo]], [[4lyo\|4lyo]], [[1kip\|1kip]], [[1ic7\|1ic7]], [[1lzt\|1lzt]], [[2xbr\|2xbr]], [[1lys\|1lys]], [[1bwj\|1bwj]], [[1e8l\|1e8l]], [[132l\|132l]], [[1sfg\|1sfg]], [[1kxw\|1kxw]], [[2x0a\|2x0a]], [[2c8o\|2c8o]], [[1g7l\|1g7l]], [[1sf4\|1sf4]], [[1yl1\|1yl1]], [[1h87\|1h87]], [[3lyt\|3lyt]], [[1iot\|1iot]], [[1dpx\|1dpx]], [[1v7s\|1v7s]], [[1ja6\|1ja6]], [[1ir8\|1ir8]], [[1uie\|1uie]], [[1lji\|1lji]], [[1bwi\|1bwi]], [[2iff\|2iff]], [[1jj0\|1jj0]], [[1rfp\|1rfp]], [[1jiy\|1jiy]], [[1iee\|1iee]], [[1xek\|1xek]], [[1at6\|1at6]], [[2ydg\|2ydg]], [[1mlc\|1mlc]], [[2b5z\|2b5z]], [[193l\|193l]], [[1lsz\|1lsz]], [[2ybm\|2ybm]], [[1sq2\|1sq2]], [[2ybh\|2ybh]], [[1vdq\|1vdq]], [[1lje\|1lje]], [[1b2k\|1b2k]], [[2ybj\|2ybj]], [[9lyz\|9lyz]], [[1uia\|1uia]], [[1hen\|1hen]], [[1xfp\|1xfp]], [[1lsd\|1lsd]], [[2blx\|2blx]], [[6lyz\|6lyz]], [[1nbz\|1nbz]], [[1lsg\|1lsg]], [[3hfm\|3hfm]], [[1ved\|1ved]], [[1lyz\|1lyz]], [[1uuz\|1uuz]], [[2xbs\|2xbs]], [[2d4i\|2d4i]], [[1fdl\|1fdl]], [[1gxx\|1gxx]], [[1lzh\|1lzh]], [[1jj3\|1jj3]], [[1yky\|1yky]], [[1kiq\|1kiq]], [[1heq\|1heq]], [[1uih\|1uih]], [[2lzh\|2lzh]], [[1kxy\|1kxy]], [[2w1l\|2w1l]], [[1g7j\|1g7j]], [[1bhz\|1bhz]], [[1wtm\|1wtm]], [[1hep\|1hep]], [[1jtt\|1jtt]], [[1lza\|1lza]], [[3zvq\|3zvq]], [[1jpo\|1jpo]], [[1j1p\|1j1p]], [[1ljj\|1ljj]], [[1f0w\|1f0w]], [[2w1x\|2w1x]], [[1lzg\|1lzg]], [[1lzc\|1lzc]], [[1rcm\|1rcm]], [[1uid\|1uid]], [[1bgi\|1bgi]], [[1lzd\|1lzd]], [[1lcn\|1lcn]], [[1hew\|1hew]], [[2vb1\|2vb1]], [[2aub\|2aub]], [[1j1x\|1j1x]], [[1ios\|1ios]], [[2cgi\|2cgi]], [[1uc0\|1uc0]], [[1azf\|1azf]], [[4lyz\|4lyz]], [[1gpq\|1gpq]], [[2a6u\|2a6u]], [[2d4k\|2d4k]], [[1bvx\|1bvx]], [[1uig\|1uig]], [[4a7d\|4a7d]], [[1qtk\|1qtk]], [[1lkr\|1lkr]], [[1hsw\|1hsw]], [[1jto\|1jto]], [[5lyz\|5lyz]], [[3lzt\|3lzt]], [[1ndm\|1ndm]], [[1sf6\|1sf6]], [[2lyz\|2lyz]], [[1fly\|1fly]], [[1yl0\|1yl0]], [[1j1o\|1j1o]], [[2lzt\|2lzt]], [[1lsy\|1lsy]], [[1uco\|1uco]], [[5lym\|5lym]], [[1lsa\|1lsa]], [[1hem\|1hem]], [[1f3j\|1f3j]], [[2a7f\|2a7f]], [[194l\|194l]], [[1lz8\|1lz8]], [[1ykx\|1ykx]], [[1vdt\|1vdt]], [[1lsn\|1lsn]], [[1g7i\|1g7i]], [[1vdp\|1vdp]]</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.107 3.4.21.107] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a8a RCSB], [http://www.ebi.ac.uk/pdbsum/4a8a PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The HtrA protein family combines chaperone and protease activities and is essential for protein quality control in many organisms. Whereas the mechanisms underlying the proteolytic function of HtrA proteins are well characterized, their chaperone activity remains poorly understood. Here we describe cryo-EM structures of Escherichia coli DegQ in its 12- and 24-mer states in complex with model substrates, providing a structural model of HtrA chaperone action. Up to six lysozyme substrates bind inside the DegQ 12-mer cage and are visualized in a close-to-native state. An asymmetric reconstruction reveals the binding of a well-ordered lysozyme to four DegQ protomers. DegQ PDZ domains are located adjacent to substrate density and their presence is required for chaperone activity. The substrate-interacting regions appear conserved in 12- and 24-mer cages, suggesting a common mechanism of chaperone function.

	~~{{STRUCTURE_4a8a\| PDB=4a8a \| SCENE= }}~~		Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ.,Malet H, Canellas F, Sawa J, Yan J, Thalassinos K, Ehrmann M, Clausen T, Saibil HR Nat Struct Mol Biol. 2012 Jan 15;19(2):152-7. doi: 10.1038/nsmb.2210. PMID:22245966<ref>PMID:22245966</ref>

	~~===Asymmetric cryo-EM reconstruction~~ of E. ~~coli DegQ 12-mer in complex with lysozyme===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22245966}}~~

	~~==About this Structure==~~
	~~[[4a8a]] is a 13 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http:/~~/~~oca.weizmann.ac.il/oca-bin/ocashort?id=4A8A OCA].~~

	==See Also==		==See Also==
	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]		*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:022245966<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Canellas, F.]]		[[Category: Canellas, F]]
	[[Category: Clausen, T.]]		[[Category: Clausen, T]]
	[[Category: Ehrmann, M.]]		[[Category: Ehrmann, M]]
	[[Category: Malet, H.]]		[[Category: Malet, H]]
	[[Category: Saibil, H R.]]		[[Category: Saibil, H R]]
	[[Category: Sawa, J.]]		[[Category: Sawa, J]]
	[[Category: Thalassinos, K.]]		[[Category: Thalassinos, K]]
	[[Category: Yan, J.]]		[[Category: Yan, J]]
	[[Category: Chaperone]]		[[Category: Chaperone]]
	[[Category: Hydrolase-hydrolase complex]]		[[Category: Hydrolase-hydrolase complex]]