4b4e - Revision history

OCA at 07:17, 1 May 2024

2024-05-01T07:17:12Z

← Older revision		Revision as of 07:17, 1 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4E FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2~~-~~METHYLPENTANE-2~~,~~4-DIOL'>MRD</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]~~</~~div~~><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.~~2~~.1.17 3.~~2~~.1.17]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [https://pdbe.org/4b4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [https://www.ebi.ac.uk/pdbsum/4b4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [https://pdbe.org/4b4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [https://www.ebi.ac.uk/pdbsum/4b4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Chiral control of crystallization has ample precedent in the small-molecule world, but relatively little is known about the role of chirality in protein crystallization. In this study, lysozyme was crystallized in the presence of the chiral additive 2-methyl-2,4-pentanediol (MPD) separately using the R and S enantiomers as well as with a racemic RS mixture. Crystals grown with (R)-MPD had the most order and produced the highest resolution protein structures. This result is consistent with the observation that in the crystals grown with (R)-MPD and (RS)-MPD the crystal contacts are made by (R)-MPD, demonstrating that there is preferential interaction between lysozyme and this enantiomer. These findings suggest that chiral interactions are important in protein crystallization.

	Crystallization of lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol.,Stauber M, Jakoncic J, Berger J, Karp JM, Axelbaum A, Sastow D, Buldyrev SV, Hrnjez BJ, Asherie N Acta Crystallogr D Biol Crystallogr. 2015 Mar 1;71(Pt 3):427-41. doi:, 10.1107/S1399004714025061. Epub 2015 Feb 26. PMID:25760593<ref>PMID:25760593</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4b4e" style="background-color:#fffaf0;"></div~~>

	==See Also==		==See Also==
Line 29:		Line 19:
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Lysozyme]]~~		[[Category: Asherie N]]
	[[Category: Asherie, N]]		[[Category: Axelbaum A]]
	[[Category: Axelbaum, A]]		[[Category: Berger J]]
	[[Category: Berger, J]]		[[Category: Jakoncic J]]
	[[Category: Jakoncic, J]]		[[Category: Stauber M]]
	[[Category: Stauber, M]]
	~~[[Category: Chirality]]~~
	~~[[Category: Hydrolase~~]]

OCA at 06:59, 31 August 2022

2022-08-31T06:59:27Z

← Older revision		Revision as of 06:59, 31 August 2022
Line 3:		Line 3:
	<StructureSection load='4b4e' size='340' side='right'caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='4b4e' size='340' side='right'caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4B4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [~~http~~://pdbe.org/4b4e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4b4e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [https://pdbe.org/4b4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [https://www.ebi.ac.uk/pdbsum/4b4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:20, 13 March 2019

2019-03-13T13:20:55Z

← Older revision		Revision as of 13:20, 13 March 2019
Line 1:		Line 1:

	==1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol==		==1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol==
	<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='4b4e' size='340' side='right'caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>
Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Chick~~]]		[[Category: Gallus gallus]]
			[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Asherie, N]]		[[Category: Asherie, N]]

OCA at 17:05, 2 January 2017

2017-01-02T17:05:59Z

← Older revision		Revision as of 17:05, 2 January 2017
Line 1:		Line 1:

	==1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol==		==1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol==
	<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [http://www.ebi.ac.uk/pdbsum/4b4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [http://pdbe.org/4b4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [http://www.ebi.ac.uk/pdbsum/4b4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4b4e" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:08, 26 March 2015

2015-03-26T08:08:53Z

← Older revision		Revision as of 08:08, 26 March 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Chiral control of crystallization has ample precedent in the small-molecule world, but relatively little is known about the role of chirality in protein crystallization. In this study, lysozyme was crystallized in the presence of the chiral additive 2-methyl-2,4-pentanediol (MPD) separately using the R and S enantiomers as well as with a racemic RS mixture. Crystals grown with (R)-MPD had the most order and produced the highest resolution protein structures. This result is consistent with the observation that in the crystals grown with (R)-MPD and (RS)-MPD the crystal contacts are made by (R)-MPD, demonstrating that there is preferential interaction between lysozyme and this enantiomer. These findings suggest that chiral interactions are important in protein crystallization.

			Crystallization of lysozyme with (R)-, (S)- and (RS)-2-methyl-2,4-pentanediol.,Stauber M, Jakoncic J, Berger J, Karp JM, Axelbaum A, Sastow D, Buldyrev SV, Hrnjez BJ, Asherie N Acta Crystallogr D Biol Crystallogr. 2015 Mar 1;71(Pt 3):427-41. doi:, 10.1107/S1399004714025061. Epub 2015 Feb 26. PMID:25760593<ref>PMID:25760593</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==

OCA at 06:18, 11 March 2015

2015-03-11T06:18:15Z

← Older revision		Revision as of 06:18, 11 March 2015
Line 2:		Line 2:
	<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gallus_gallus Gallus gallus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>
Line 17:		Line 17:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Gallus gallus~~]]		[[Category: Chick]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Asherie, N]]		[[Category: Asherie, N]]

OCA at 17:15, 25 December 2014

2014-12-25T17:15:14Z

← Older revision		Revision as of 17:15, 25 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_4b4e\| PDB=4b4e \| SCENE= }}~~		==1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol==
	===1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol===		<StructureSection load='4b4e' size='340' side='right' caption='[[4b4e]], [[Resolution\|resolution]] 1.00Å' scene=''>
			== Structural highlights ==
	==~~Function~~==		<table><tr><td colspan='2'>[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4E FirstGlance]. <br>
	[[~~http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK~~]] ~~Lysozymes have primarily a bacteriolytic function~~; ~~those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref~~>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4b49\|4b49]], [[4b4i\|4b4i]], [[4b4j\|4b4j]]</td></tr>
	==~~About this Structure~~==		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
	[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA].		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b4e RCSB], [http://www.ebi.ac.uk/pdbsum/4b4e PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>

	==See Also==		==See Also==
	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]		*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
			== References ==
	==~~Reference~~==		<references/>
	<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Asherie, N.]]		[[Category: Asherie, N]]
	[[Category: Axelbaum, A.]]		[[Category: Axelbaum, A]]
	[[Category: Berger, J.]]		[[Category: Berger, J]]
	[[Category: Jakoncic, J.]]		[[Category: Jakoncic, J]]
	[[Category: Stauber, M.]]		[[Category: Stauber, M]]
	[[Category: Chirality]]		[[Category: Chirality]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:44, 27 March 2013

2013-03-27T07:44:39Z

← Older revision		Revision as of 07:44, 27 March 2013
Line 1:		Line 1:
	~~[[Image:4b4e.jpg\|left\|200px]]~~

	{{STRUCTURE_4b4e\| PDB=4b4e \| SCENE= }}		{{STRUCTURE_4b4e\| PDB=4b4e \| SCENE= }}

	===1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol===		===1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol===

			==Function==
			[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>

	==About this Structure==		==About this Structure==
	[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA].		[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA].

			==See Also==
			*[[Hen Egg-White (HEW) Lysozyme\|Hen Egg-White (HEW) Lysozyme]]

			==Reference==
			<references group="xtra"/><references/>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]

OCA at 06:04, 22 August 2012

2012-08-22T06:04:39Z

← Older revision		Revision as of 06:04, 22 August 2012
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		[[Image:4b4e.jpg\|left\|200px]]

	~~The entry~~ 4b4e ~~is ON HOLD~~		{{STRUCTURE_4b4e\| PDB=4b4e \| SCENE= }}

	~~Authors: Jakoncic, J~~., ~~Berger, J., Stauber, M., Asherie, N.~~		===1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol===

	~~Description~~: 1.00 A ~~Structure of Lysozyme Crystallized with (R)-2-methyl-2~~,~~4-pentanediol~~
			==About this Structure==
			[[4b4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4E OCA].
			[[Category: Gallus gallus]]
			[[Category: Lysozyme]]
			[[Category: Asherie, N.]]
			[[Category: Axelbaum, A.]]
			[[Category: Berger, J.]]
			[[Category: Jakoncic, J.]]
			[[Category: Stauber, M.]]
			[[Category: Chirality]]
			[[Category: Hydrolase]]

OCA: Protected "4b4e" [edit=sysop:move=sysop]

2012-08-08T04:47:17Z

Protected "4b4e" [edit=sysop:move=sysop]

← Older revision	Revision as of 04:47, 8 August 2012
(No difference)