4bot - Revision history

OCA at 07:20, 31 August 2022

2022-08-31T07:20:41Z

← Older revision		Revision as of 07:20, 31 August 2022
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	<SX load='4bot' size='340' side='right' viewer='molstar' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>		<SX load='4bot' size='340' side='right' viewer='molstar' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4BOT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [~~http~~://pdbe.org/4bot PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bot PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bot ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [https://pdbe.org/4bot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [https://www.ebi.ac.uk/pdbsum/4bot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bot ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.		[[https://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 18:56, 10 April 2020

2020-04-10T18:56:30Z

← Older revision		Revision as of 18:56, 10 April 2020
Line 3:		Line 3:
	<SX load='4bot' size='340' side='right' viewer='molstar' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>		<SX load='4bot' size='340' side='right' viewer='molstar' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BOT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [http://pdbe.org/4bot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [http://www.ebi.ac.uk/pdbsum/4bot PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bot ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [http://pdbe.org/4bot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [http://www.ebi.ac.uk/pdbsum/4bot PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bot ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:50, 6 March 2020

2020-03-06T17:50:51Z

← Older revision		Revision as of 17:50, 6 March 2020
Line 1:		Line 1:

	==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==		==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==
	<~~StructureSection~~ load='4bot' size='340' side='right'caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>		<SX load='4bot' size='340' side='right' viewer='molstar' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
	</~~StructureSection~~>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Torpedo marmorata]]		[[Category: Torpedo marmorata]]

OCA at 16:34, 28 August 2019

2019-08-28T16:34:49Z

← Older revision		Revision as of 16:34, 28 August 2019
Line 1:		Line 1:

	==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==		==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==
	<StructureSection load='4bot' size='340' side='right' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>		<StructureSection load='4bot' size='340' side='right'caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4bot" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4bot" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Nicotinic Acetylcholine Receptor\|Nicotinic Acetylcholine Receptor]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Torpedo marmorata]]		[[Category: Torpedo marmorata]]
	[[Category: Unwin, N]]		[[Category: Unwin, N]]

OCA at 02:39, 16 November 2017

2017-11-16T02:39:31Z

← Older revision		Revision as of 02:39, 16 November 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4bot" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4bot" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Nicotinic Acetylcholine Receptor\|Nicotinic Acetylcholine Receptor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:31, 5 August 2016

2016-08-05T21:31:30Z

← Older revision		Revision as of 21:31, 5 August 2016
Line 1:		Line 1:

	==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==		==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==
	<StructureSection load='4bot' size='340' side='right' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>		<StructureSection load='4bot' size='340' side='right' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [http://www.ebi.ac.uk/pdbsum/4bot PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [http://pdbe.org/4bot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [http://www.ebi.ac.uk/pdbsum/4bot PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bot ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4bot" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Nicotinic Acetylcholine Receptor\|Nicotinic Acetylcholine Receptor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:04, 25 December 2014

2014-12-25T22:04:30Z

← Older revision		Revision as of 22:04, 25 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_4bot\| PDB=4bot \| SCENE= }}~~		==The structure and super-organization of acetylcholine receptor- rapsyn complexes class E==
	===The structure and super-organization of acetylcholine receptor- rapsyn complexes class E===		<StructureSection load='4bot' size='340' side='right' caption='[[4bot]], [[Resolution\|resolution]] 42.00Å' scene=''>
	~~{{ABSTRACT_PUBMED_23754381}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BOT FirstGlance]. <br>
	==Function==		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4bog\|4bog]], [[4boi\|4boi]], [[4bon\|4bon]], [[4boo\|4boo]], [[4bor\|4bor]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bot RCSB], [http://www.ebi.ac.uk/pdbsum/4bot PDBsum]</span></td></tr>
			</table>
			== Function ==
	[[http://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.		[[http://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The scaffolding protein at the neuromuscular junction, rapsyn, enables clustering of nicotinic acetylcholine receptors in high concentration and is critical for muscle function. Patients with insufficient receptor clustering suffer from muscle weakness. However, the detailed organization of the receptor-rapsyn network is poorly understood: it is unclear whether rapsyn first forms a wide meshwork to which receptors can subsequently dock or whether it only forms short bridges linking receptors together to make a large cluster. Furthermore, the number of rapsyn-binding sites per receptor (a heteropentamer) has been controversial. Here, we show by cryoelectron tomography and subtomogram averaging of Torpedo postsynaptic membrane that receptors are connected by up to three rapsyn bridges, the minimum number required to form a 2D network. Half of the receptors belong to rapsyn-connected groups comprising between two and fourteen receptors. Our results provide a structural basis for explaining the stability and low diffusion of receptors within clusters.

	~~==About this~~ Structure==		Structure and superorganization of acetylcholine receptor-rapsyn complexes.,Zuber B, Unwin N Proc Natl Acad Sci U S A. 2013 Jun 10. PMID:23754381<ref>PMID:23754381</ref>
	~~[[4bot]] is a 5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Torpedo_marmorata Torpedo marmorata]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA].~~

	==~~Reference~~==		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~<ref group="xtra">PMID:023754381</ref>~~<references ~~group="xtra"~~/><~~references~~/>		</div>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Torpedo marmorata]]		[[Category: Torpedo marmorata]]
	[[Category: Unwin, N.]]		[[Category: Unwin, N]]
	[[Category: Zuber, B~~.]]~~		[[Category: Zuber, B]]
	~~[[Category: 43k~~]]
	[[Category: Clustering]]		[[Category: Clustering]]
	[[Category: Neuromuscular junction]]		[[Category: Neuromuscular junction]]

OCA at 10:15, 30 June 2013

2013-06-30T10:15:52Z

← Older revision		Revision as of 10:15, 30 June 2013
Line 1:		Line 1:
	~~'''Unreleased~~ structure~~'''~~		{{STRUCTURE_4bot\| PDB=4bot \| SCENE= }}
			===The structure and super-organization of acetylcholine receptor- rapsyn complexes class E===
			{{ABSTRACT_PUBMED_23754381}}

	~~The entry 4bot is ON HOLD until Paper Publication~~		==Function==
			[[http://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

	~~Authors~~: ~~Zuber, B~~.~~, Unwin, N~~.		==About this Structure==
			[[4bot]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BOT OCA].

	~~Description~~: ~~The structure and super-organization of acetylcholine~~ receptor~~-rapsyn complexes class E~~		==Reference==
			<ref group="xtra">PMID:023754381</ref><references group="xtra"/><references/>
			[[Category: Torpedo marmorata]]
			[[Category: Unwin, N.]]
			[[Category: Zuber, B.]]
			[[Category: 43k]]
			[[Category: Clustering]]
			[[Category: Neuromuscular junction]]
			[[Category: Neurotransmitter receptor]]
			[[Category: Nicotinic]]
			[[Category: Synapse]]
			[[Category: Transport protein]]

OCA: Protected "4bot" [edit=sysop:move=sysop]

2013-06-19T10:51:13Z

Protected "4bot" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:51, 19 June 2013
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4bot is ON HOLD until Paper Publication Authors: Zuber, B., Unwin, N. Description: The structure and super-organization of acetylcholine receptor-r...

2013-06-19T10:51:11Z

New page: '''Unreleased structure''' The entry 4bot is ON HOLD until Paper Publication Authors: Zuber, B., Unwin, N. Description: The structure and super-organization of acetylcholine receptor-r...

New page

'''Unreleased structure'''

The entry 4bot is ON HOLD until Paper Publication

Authors: Zuber, B., Unwin, N.

Description: The structure and super-organization of acetylcholine receptor-rapsyn complexes class E