4bub - Revision history

OCA at 08:17, 9 October 2024

2024-10-09T08:17:05Z

← Older revision		Revision as of 08:17, 9 October 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BUB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BUB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [https://pdbe.org/4bub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [https://www.ebi.ac.uk/pdbsum/4bub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [https://pdbe.org/4bub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [https://www.ebi.ac.uk/pdbsum/4bub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>		[https://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Peptidoglycan is a major determinant of cell shape in bacteria, and its biosynthesis involves the concerted action of cytoplasmic, membrane-associated and periplasmic enzymes. Within the cytoplasm, Mur enzymes catalyse the first steps leading to peptidoglycan precursor biosynthesis, and have been suggested as being part of a multicomponent complex that could also involve the transglycosylase MurG and the cytoskeletal protein MreB. In order to initialize the characterization of a potential Mur interaction network, we purified MurD, MurE, MurF, MurG and MreB from Thermotoga maritima and characterized their interactions using membrane blotting and surface plasmon resonance. MurD, MurE and MurF all recognize MurG and MreB, but not each other, while the two latter proteins interact. In addition, we solved the crystal structures of MurD, MurE and MurF, which indicate that their C-termini display high conformational flexibilities. The differences in Mur conformations could be important parameters for the stability of an intracytoplasmic murein biosynthesis complex.

			MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.,Favini-Stabile S, Contreras-Martel C, Thielens N, Dessen A Environ Microbiol. 2013 Jun 3. doi: 10.1111/1462-2920.12171. PMID:23826965<ref>PMID:23826965</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 4bub" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 17:08, 7 September 2022

2022-09-07T17:08:36Z

← Older revision		Revision as of 17:08, 7 September 2022
Line 3:		Line 3:
	<StructureSection load='4bub' size='340' side='right'caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4bub' size='340' side='right'caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4BUB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BUB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>~~</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [https://pdbe.org/4bub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [https://www.ebi.ac.uk/pdbsum/4bub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4buc\|4buc]]~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [~~http~~://pdbe.org/4bub PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4bub PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>		[[https://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Peptidoglycan is a major determinant of cell shape in bacteria, and its biosynthesis involves the concerted action of cytoplasmic, membrane-associated and periplasmic enzymes. Within the cytoplasm, Mur enzymes catalyse the first steps leading to peptidoglycan precursor biosynthesis, and have been suggested as being part of a multicomponent complex that could also involve the transglycosylase MurG and the cytoskeletal protein MreB. In order to initialize the characterization of a potential Mur interaction network, we purified MurD, MurE, MurF, MurG and MreB from Thermotoga maritima and characterized their interactions using membrane blotting and surface plasmon resonance. MurD, MurE and MurF all recognize MurG and MreB, but not each other, while the two latter proteins interact. In addition, we solved the crystal structures of MurD, MurE and MurF, which indicate that their C-termini display high conformational flexibilities. The differences in Mur conformations could be important parameters for the stability of an intracytoplasmic murein biosynthesis complex.

	MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.,Favini-Stabile S, Contreras-Martel C, Thielens N, Dessen A Environ Microbiol. 2013 Jun 3. doi: 10.1111/1462-2920.12171. PMID:23826965<ref>PMID:23826965</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4bub" style="background-color:#fffaf0;"></div~~>

	==See Also==		==See Also==
Line 27:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 43589]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Contreras-Martel, C]]		[[Category: Thermotoga maritima]]
	[[Category: Dessen, A]]		[[Category: Contreras-Martel C]]
	[[Category: Favini-Stabile, S]]		[[Category: Dessen A]]
	[[Category: Thielens, N]]		[[Category: Favini-Stabile S]]
	~~[[Category: Adp-forming enzyme]]~~		[[Category: Thielens N]]
	~~[[Category: Atp- binding]]~~
	~~[[Category: Cell cycle]]~~
	~~[[Category: Cell division]]~~
	~~[[Category: Cell shape]]~~
	~~[[Category: Cell wall]]~~
	~~[[Category: Ligase]]~~
	~~[[Category: Mure]]~~
	~~[[Category: Nucleotide-binding]]~~
	~~[[Category: Peptidoglycan synthesis~~]]

OCA at 13:12, 13 March 2019

2019-03-13T13:12:02Z

← Older revision		Revision as of 13:12, 13 March 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==		==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==
	<StructureSection load='4bub' size='340' side='right' caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4bub' size='340' side='right'caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BUB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BUB FirstGlance]. <br>
Line 22:		Line 22:

	==See Also==		==See Also==
	*[[~~MurD~~ ligase\|~~MurD~~ ligase]]		*[[Mur ligase\|Mur ligase]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
			[[Category: Large Structures]]
	[[Category: Contreras-Martel, C]]		[[Category: Contreras-Martel, C]]
	[[Category: Dessen, A]]		[[Category: Dessen, A]]

OCA at 21:17, 5 August 2016

2016-08-05T21:17:57Z

← Older revision		Revision as of 21:17, 5 August 2016
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==		==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==
	<StructureSection load='4bub' size='340' side='right' caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='4bub' size='340' side='right' caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4buc\|4buc]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4buc\|4buc]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [http://www.ebi.ac.uk/pdbsum/4bub PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [http://pdbe.org/4bub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [http://www.ebi.ac.uk/pdbsum/4bub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4bub" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 05:58, 25 December 2014

2014-12-25T05:58:29Z

← Older revision		Revision as of 05:58, 25 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_4bub\| PDB=4bub \| SCENE= }}~~		==CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP==
	===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP===		<StructureSection load='4bub' size='340' side='right' caption='[[4bub]], [[Resolution\|resolution]] 2.90Å' scene=''>
	~~{{ABSTRACT_PUBMED_23826965}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BUB FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4buc\|4buc]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bub RCSB], [http://www.ebi.ac.uk/pdbsum/4bub PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Peptidoglycan is a major determinant of cell shape in bacteria, and its biosynthesis involves the concerted action of cytoplasmic, membrane-associated and periplasmic enzymes. Within the cytoplasm, Mur enzymes catalyse the first steps leading to peptidoglycan precursor biosynthesis, and have been suggested as being part of a multicomponent complex that could also involve the transglycosylase MurG and the cytoskeletal protein MreB. In order to initialize the characterization of a potential Mur interaction network, we purified MurD, MurE, MurF, MurG and MreB from Thermotoga maritima and characterized their interactions using membrane blotting and surface plasmon resonance. MurD, MurE and MurF all recognize MurG and MreB, but not each other, while the two latter proteins interact. In addition, we solved the crystal structures of MurD, MurE and MurF, which indicate that their C-termini display high conformational flexibilities. The differences in Mur conformations could be important parameters for the stability of an intracytoplasmic murein biosynthesis complex.

	~~==Function==~~		MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.,Favini-Stabile S, Contreras-Martel C, Thielens N, Dessen A Environ Microbiol. 2013 Jun 3. doi: 10.1111/1462-2920.12171. PMID:23826965<ref>PMID:23826965</ref>
	~~[[http://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes~~ the ~~addition~~ of ~~both L~~- ~~and D-lysine to the nucleotide precursor UDP~~-N-~~acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan~~. ~~Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently~~.<ref>PMID:~~16595662~~</ref>

	~~==About this Structure==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[4bub]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Atcc_43589 Atcc 43589]~~. ~~Full crystallographic information is available from [http:/~~/~~oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA].~~		</div>

	==~~Reference~~==		==See Also==
	~~<ref group~~=~~"xtra">PMID:023826965</ref>~~<references ~~group="xtra"~~/><~~references~~/>		*[[MurD ligase\|MurD ligase]]
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
	[[Category: Contreras-Martel, C.]]		[[Category: Contreras-Martel, C]]
	[[Category: Dessen, A.]]		[[Category: Dessen, A]]
	[[Category: Favini-Stabile, S.]]		[[Category: Favini-Stabile, S]]
	[[Category: Thielens, N.]]		[[Category: Thielens, N]]
	[[Category: Adp-forming enzyme]]		[[Category: Adp-forming enzyme]]
	[[Category: Atp- binding]]		[[Category: Atp- binding]]

OCA at 08:07, 18 December 2013

2013-12-18T08:07:21Z

← Older revision		Revision as of 08:07, 18 December 2013
Line 2:		Line 2:
	===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP===		===CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP===
	{{ABSTRACT_PUBMED_23826965}}		{{ABSTRACT_PUBMED_23826965}}

			==Function==
			[[http://www.uniprot.org/uniprot/MURE_THEMA MURE_THEMA]] Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.<ref>PMID:16595662</ref>

	==About this Structure==		==About this Structure==
	[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA].		[[4bub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BUB OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/>
	[[Category: ~~Thermotoga maritima~~]]		[[Category: Atcc 43589]]
	[[Category: Contreras-Martel, C.]]		[[Category: Contreras-Martel, C.]]
	[[Category: Dessen, A.]]		[[Category: Dessen, A.]]

OCA at 04:57, 18 July 2013

2013-07-18T04:57:47Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4bub|  PDB=4bub  |  SCENE=  }}
-The entry 4bub is ON HOLD  until Paper Publication
+==About this Structure==
-Authors: FAVINI-STABILE, S., CONTRERAS-MARTEL, C., THIELENS, N., DESSEN, A.
+==Reference==
+<ref group="xtra">PMID:023826965</ref><references group="xtra"/><references/>
-Description: CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP
+[[Category: Thermotoga maritima]]

OCA: Protected "4bub" [edit=sysop:move=sysop]

2013-06-30T08:30:48Z

Protected "4bub" [edit=sysop:move=sysop]

← Older revision	Revision as of 08:30, 30 June 2013
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4bub is ON HOLD until Paper Publication Authors: FAVINI-STABILE, S., CONTRERAS-MARTEL, C., THIELENS, N., DESSEN, A. Description: CRYSTAL STRUCTURE ...

2013-06-30T08:30:47Z

New page: '''Unreleased structure''' The entry 4bub is ON HOLD until Paper Publication Authors: FAVINI-STABILE, S., CONTRERAS-MARTEL, C., THIELENS, N., DESSEN, A. Description: CRYSTAL STRUCTURE ...

New page

'''Unreleased structure'''

The entry 4bub is ON HOLD until Paper Publication

Authors: FAVINI-STABILE, S., CONTRERAS-MARTEL, C., THIELENS, N., DESSEN, A.

Description: CRYSTAL STRUCTURE OF MURE LIGASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ADP