4css - Revision history

OCA at 12:15, 20 December 2023

2023-12-20T12:15:56Z

← Older revision		Revision as of 12:15, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CSS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CSS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.069Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [https://pdbe.org/4css PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [https://www.ebi.ac.uk/pdbsum/4css PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [https://pdbe.org/4css PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [https://www.ebi.ac.uk/pdbsum/4css PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.		[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:31, 14 September 2022

2022-09-14T07:31:26Z

← Older revision		Revision as of 07:31, 14 September 2022
Line 3:		Line 3:
	<StructureSection load='4css' size='340' side='right'caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='4css' size='340' side='right'caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4CSS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CSS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]~~</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [https://pdbe.org/4css PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [https://www.ebi.ac.uk/pdbsum/4css PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [~~http~~://pdbe.org/4css PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4css PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.		[[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Ecoli~~]]		[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Abgottspon, D]]		[[Category: Abgottspon D]]
	[[Category: Eris, D]]		[[Category: Eris D]]
	[[Category: Ernst, B]]		[[Category: Ernst B]]
	[[Category: Hutter, A]]		[[Category: Hutter A]]
	[[Category: Jakob~~, R P~~]]		[[Category: Jakob RP]]
	[[Category: Jian, X]]		[[Category: Jian X]]
	[[Category: Kleeb, S]]		[[Category: Kleeb S]]
	[[Category: Luedin, N]]		[[Category: Luedin N]]
	[[Category: Maier, T]]		[[Category: Maier T]]
	[[Category: Mayer, K]]		[[Category: Mayer K]]
	[[Category: Navarra, G]]		[[Category: Navarra G]]
	[[Category: Pang, L]]		[[Category: Pang L]]
	[[Category: Preston~~, R C~~]]		[[Category: Preston RC]]
	[[Category: Rabbani, S]]		[[Category: Rabbani S]]
	[[Category: Scharenberg, M]]		[[Category: Scharenberg M]]
	[[Category: Schwardt, O]]		[[Category: Schwardt O]]
	[[Category: Sharpe, T]]		[[Category: Sharpe T]]
	[[Category: Sigl, A]]		[[Category: Sigl A]]
	[[Category: Smiesko, M]]		[[Category: Smiesko M]]
	[[Category: Zihlmann, P]]		[[Category: Zihlmann P]]
	~~[[Category: Adhesin]]~~
	~~[[Category: Fimh antagonist]]~~
	~~[[Category: Sugar binding protein]]~~
	~~[[Category: Type i pili]]~~
	~~[[Category: Upec]]~~
	~~[[Category: Uti~~]]

OCA at 16:18, 28 August 2019

2019-08-28T16:18:56Z

← Older revision		Revision as of 16:18, 28 August 2019
Line 1:		Line 1:

	==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside==		==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside==
	<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='4css' size='340' side='right'caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CSS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CSS FirstGlance]. <br>
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4css" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4css" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
			[[Category: Large Structures]]
	[[Category: Abgottspon, D]]		[[Category: Abgottspon, D]]
	[[Category: Eris, D]]		[[Category: Eris, D]]

OCA at 22:22, 15 November 2017

2017-11-15T22:22:20Z

← Older revision		Revision as of 22:22, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4css]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CSS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CSS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]</td></tr>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Ecoli]]
	[[Category: Abgottspon, D]]		[[Category: Abgottspon, D]]
	[[Category: Eris, D]]		[[Category: Eris, D]]

OCA at 16:53, 2 January 2017

2017-01-02T16:53:31Z

← Older revision		Revision as of 16:53, 2 January 2017
Line 1:		Line 1:

	==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside==		==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside==
	<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [http://www.ebi.ac.uk/pdbsum/4css PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [http://pdbe.org/4css PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [http://www.ebi.ac.uk/pdbsum/4css PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4css" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:49, 25 February 2015

2015-02-25T13:49:58Z

← Older revision		Revision as of 13:49, 25 February 2015
Line 1:		Line 1:
	'''~~Unreleased~~ structure'''		==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside==
			<StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution\|resolution]] 1.07Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4css]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CSS FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4cst\|4cst]], [[4csy\|4csy]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [http://www.ebi.ac.uk/pdbsum/4css PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Urinary tract infections (UTIs), predominantly caused by uropathogenic Escherichia coli (UPEC), belong to the most prevalent infectious diseases worldwide. The attachment of UPEC to host cells is mediated by FimH, a mannose-binding adhesin at the tip of bacterial type 1 pili. To date, UTIs are mainly treated with antibiotics, leading to the ubiquitous problem of increasing resistance against most of the currently available antimicrobials. Therefore, new treatment strategies are urgently needed. Here, we describe the development of an orally available FimH antagonist. Starting from the carboxylate substituted biphenyl alpha-d-mannoside 9, affinity and the relevant pharmacokinetic parameters (solubility, permeability, renal excretion) were substantially improved by a bioisosteric approach. With 3'-chloro-4'-(alpha-d-mannopyranosyloxy)biphenyl-4-carbonitrile (10j) a FimH antagonist with an optimal in vitro PK/PD profile was identified. Orally applied, 10j was effective in a mouse model of UTI by reducing the bacterial load in the bladder by about 1000-fold.

	~~The entry 4css is ON HOLD until Paper Publication~~		FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile.,Kleeb S, Pang L, Mayer K, Eris D, Sigl A, Preston RC, Zihlmann P, Sharpe T, Jakob RP, Abgottspon D, Hutter AS, Scharenberg M, Jiang X, Navarra G, Rabbani S, Smiesko M, Ludin N, Bezencon J, Schwardt O, Maier T, Ernst B J Med Chem. 2015 Feb 20. PMID:25666045<ref>PMID:25666045</ref>

	~~Authors: Kleeb~~, ~~S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M., Jian, X., Navarra, G~~.~~, Rabbani,~~ S.~~, Smiesko, M., Luedin, N., Jakob, R.P., Schwardt, O., Maier, T., Sharpe, T., Ernst, B~~.		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside~~		== References ==
	~~[[Category: Unreleased Structures]]~~		<references/>
	~~[[Category: Maier, T]]~~		__TOC__
	~~[[Category: Rabbani, S]]~~		</StructureSection>
	~~[[Category: Pang, L]]~~		[[Category: Abgottspon, D]]
	~~[[Category: Luedin, N]]~~
	~~[[Category: Zihlmann, P]]~~
	[[Category: ~~Mayer~~, K]]
	[[Category: Eris, D]]		[[Category: Eris, D]]
	~~[[Category: Abgottspon, D]]~~
	[[Category: Ernst, B]]		[[Category: Ernst, B]]
	~~[[Category: Smiesko, M]]~~
	[[Category: Hutter, A]]		[[Category: Hutter, A]]
	[[Category: ~~Schwardt~~, O]]		[[Category: Jakob, R P]]
	[[Category: ~~Jakob~~, ~~R.P~~]]		[[Category: Jian, X]]
			[[Category: Kleeb, S]]
			[[Category: Luedin, N]]
			[[Category: Maier, T]]
			[[Category: Mayer, K]]
	[[Category: Navarra, G]]		[[Category: Navarra, G]]
			[[Category: Pang, L]]
			[[Category: Preston, R C]]
			[[Category: Rabbani, S]]
	[[Category: Scharenberg, M]]		[[Category: Scharenberg, M]]
	[[Category: ~~Preston~~, ~~R.C~~]]		[[Category: Schwardt, O]]
	[[Category: ~~Jian~~, X]]		[[Category: Sharpe, T]]
	[[Category: Sigl, A]]		[[Category: Sigl, A]]
	[[Category: ~~Kleeb~~, S]]		[[Category: Smiesko, M]]
	[[Category: ~~Sharpe~~, T]]		[[Category: Zihlmann, P]]
			[[Category: Adhesin]]
			[[Category: Fimh antagonist]]
			[[Category: Sugar binding protein]]
			[[Category: Type i pili]]
			[[Category: Upec]]
			[[Category: Uti]]

OCA at 13:31, 24 December 2014

2014-12-24T13:31:25Z

← Older revision		Revision as of 13:31, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside		Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside
			[[Category: Unreleased Structures]]
			[[Category: Maier, T]]
			[[Category: Rabbani, S]]
			[[Category: Pang, L]]
			[[Category: Luedin, N]]
			[[Category: Zihlmann, P]]
			[[Category: Mayer, K]]
			[[Category: Eris, D]]
			[[Category: Abgottspon, D]]
			[[Category: Ernst, B]]
			[[Category: Smiesko, M]]
			[[Category: Hutter, A]]
			[[Category: Schwardt, O]]
			[[Category: Jakob, R.P]]
			[[Category: Navarra, G]]
			[[Category: Scharenberg, M]]
			[[Category: Preston, R.C]]
			[[Category: Jian, X]]
			[[Category: Sigl, A]]
			[[Category: Kleeb, S]]
			[[Category: Sharpe, T]]

OCA at 08:12, 2 April 2014

2014-04-02T08:12:12Z

← Older revision		Revision as of 08:12, 2 April 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4css is ON HOLD		The entry 4css is ON HOLD until Paper Publication

	Authors: Kleeb, S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M., Jian, X., Navarra, G., Rabbani, S., Smiesko, M., Luedin, N., Jakob, R.P., Schwardt, O., Maier, T., Sharpe, T., Ernst, B.		Authors: Kleeb, S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M., Jian, X., Navarra, G., Rabbani, S., Smiesko, M., Luedin, N., Jakob, R.P., Schwardt, O., Maier, T., Sharpe, T., Ernst, B.

	Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside		Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside

OCA: Protected "4css" [edit=sysop:move=sysop]

2014-03-19T06:51:35Z

Protected "4css" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:51, 19 March 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4css is ON HOLD Authors: Kleeb, S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M...

2014-03-19T06:51:33Z

New page: '''Unreleased structure''' The entry 4css is ON HOLD Authors: Kleeb, S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M...

New page

'''Unreleased structure'''

The entry 4css is ON HOLD

Authors: Kleeb, S., Pang, L., Mayer, K., Sigl, A., Eris, D., Preston, R.C., Zihlmann, P., Abgottspon, D., Hutter, A., Scharenberg, M., Jian, X., Navarra, G., Rabbani, S., Smiesko, M., Luedin, N., Jakob, R.P., Schwardt, O., Maier, T., Sharpe, T., Ernst, B.

Description: Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside