4db2 - Revision history

OCA at 14:30, 14 March 2024

2024-03-14T14:30:30Z

← Older revision		Revision as of 14:30, 14 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [https://pdbe.org/4db2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [https://www.ebi.ac.uk/pdbsum/4db2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4db2 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.157Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [https://pdbe.org/4db2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [https://www.ebi.ac.uk/pdbsum/4db2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4db2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/MS116_YEAST MS116_YEAST]] ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.<ref>PMID:2535893</ref> <ref>PMID:7567443</ref> <ref>PMID:12402239</ref> <ref>PMID:15618406</ref>		[https://www.uniprot.org/uniprot/MS116_YEAST MS116_YEAST] ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.<ref>PMID:2535893</ref> <ref>PMID:7567443</ref> <ref>PMID:12402239</ref> <ref>PMID:15618406</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	DEAD-box proteins are the largest family of nucleic acid helicases, and are crucial to RNA metabolism throughout all domains of life. They contain a conserved 'helicase core' of two RecA-like domains (domains (D)1 and D2), which uses ATP to catalyse the unwinding of short RNA duplexes by non-processive, local strand separation. This mode of action differs from that of translocating helicases and allows DEAD-box proteins to remodel large RNAs and RNA-protein complexes without globally disrupting RNA structure. However, the structural basis for this distinctive mode of RNA unwinding remains unclear. Here, structural, biochemical and genetic analyses of the yeast DEAD-box protein Mss116p indicate that the helicase core domains have modular functions that enable a novel mechanism for RNA-duplex recognition and unwinding. By investigating D1 and D2 individually and together, we find that D1 acts as an ATP-binding domain and D2 functions as an RNA-duplex recognition domain. D2 contains a nucleic-acid-binding pocket that is formed by conserved DEAD-box protein sequence motifs and accommodates A-form but not B-form duplexes, providing a basis for RNA substrate specificity. Upon a conformational change in which the two core domains join to form a 'closed state' with an ATPase active site, conserved motifs in D1 promote the unwinding of duplex substrates bound to D2 by excluding one RNA strand and bending the other. Our results provide a comprehensive structural model for how DEAD-box proteins recognize and unwind RNA duplexes. This model explains key features of DEAD-box protein function and affords a new perspective on how the evolutionarily related cores of other RNA and DNA helicases diverged to use different mechanisms.

	Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.,Mallam AL, Del Campo M, Gilman B, Sidote DJ, Lambowitz AM Nature. 2012 Sep 2. doi: 10.1038/nature11402. PMID:22940866<ref>PMID:22940866</ref>		==See Also==
			*[[Helicase 3D structures\|Helicase 3D structures]]
	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class~~=~~"pdbe-citations 4db2" style~~=~~"background-color:#fffaf0;"></div>~~
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:09, 21 September 2022

2022-09-21T08:09:31Z

← Older revision		Revision as of 08:09, 21 September 2022
Line 1:		Line 1:

	==Mss116p DEAD-box helicase domain 2 bound to an RNA duplex==		==Mss116p DEAD-box helicase domain 2 bound to an RNA duplex==
	<StructureSection load='4db2' size='340' side='right' caption='[[4db2]], [[Resolution\|resolution]] 3.16Å' scene=''>		<StructureSection load='4db2' size='340' side='right'caption='[[4db2]], [[Resolution\|resolution]] 3.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>
	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dax\|4dax]], [[4daz\|4daz]], [[4db4\|4db4]]</td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [https://pdbe.org/4db2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [https://www.ebi.ac.uk/pdbsum/4db2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4db2 ProSAT]</span></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MSS116, YDR194C, YD9346.05C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [~~http~~://pdbe.org/4db2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4db2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4db2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/MS116_YEAST MS116_YEAST]] ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.<ref>PMID:2535893</ref> <ref>PMID:7567443</ref> <ref>PMID:12402239</ref> <ref>PMID:15618406</ref>		[[https://www.uniprot.org/uniprot/MS116_YEAST MS116_YEAST]] ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.<ref>PMID:2535893</ref> <ref>PMID:7567443</ref> <ref>PMID:12402239</ref> <ref>PMID:15618406</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Atcc 18824~~]]		[[Category: Large Structures]]
	[[Category: ~~RNA helicase~~]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Campo, M ~~Del~~]]		[[Category: Del Campo M]]
	[[Category: Gilman~~, B D~~]]		[[Category: Gilman BD]]
	[[Category: Lambowitz, A]]		[[Category: Lambowitz A]]
	[[Category: Mallam~~, A L~~]]		[[Category: Mallam AL]]
	[[Category: Sidote~~, D J]]~~		[[Category: Sidote DJ]]
	~~[[Category: Dead-box]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Rna binding protein-rna complex]]~~
	~~[[Category: Rna helicase~~]]

OCA at 10:13, 5 August 2016

2016-08-05T10:13:08Z

← Older revision		Revision as of 10:13, 5 August 2016
Line 1:		Line 1:

	==Mss116p DEAD-box helicase domain 2 bound to an RNA duplex==		==Mss116p DEAD-box helicase domain 2 bound to an RNA duplex==
	<StructureSection load='4db2' size='340' side='right' caption='[[4db2]], [[Resolution\|resolution]] 3.16Å' scene=''>		<StructureSection load='4db2' size='340' side='right' caption='[[4db2]], [[Resolution\|resolution]] 3.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dax\|4dax]], [[4daz\|4daz]], [[4db4\|4db4]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dax\|4dax]], [[4daz\|4daz]], [[4db4\|4db4]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MSS116, YDR194C, YD9346.05C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MSS116, YDR194C, YD9346.05C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [http://www.ebi.ac.uk/pdbsum/4db2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [http://pdbe.org/4db2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [http://www.ebi.ac.uk/pdbsum/4db2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4db2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4db2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Atcc 18824]]
	[[Category: RNA helicase]]		[[Category: RNA helicase]]
	~~[[Category: Saccharomyces cerevisiae]]~~
	[[Category: Campo, M Del]]		[[Category: Campo, M Del]]
	[[Category: Gilman, B D]]		[[Category: Gilman, B D]]

OCA at 01:30, 25 December 2014

2014-12-25T01:30:43Z

← Older revision		Revision as of 01:30, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [http://www.ebi.ac.uk/pdbsum/4db2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [http://www.ebi.ac.uk/pdbsum/4db2 PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/MS116_YEAST MS116_YEAST]] ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.<ref>PMID:2535893</ref> <ref>PMID:7567443</ref> <ref>PMID:12402239</ref> <ref>PMID:15618406</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:39, 9 December 2014

2014-12-09T17:39:23Z

← Older revision		Revision as of 17:39, 9 December 2014
Line 1:		Line 1:
	[[~~Image~~:~~4db2~~.~~png~~\|~~left~~\|~~200px~~]]		==Mss116p DEAD-box helicase domain 2 bound to an RNA duplex==
			<StructureSection load='4db2' size='340' side='right' caption='[[4db2]], [[Resolution\|resolution]] 3.16Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4db2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DB2 FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dax\|4dax]], [[4daz\|4daz]], [[4db4\|4db4]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MSS116, YDR194C, YD9346.05C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4db2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4db2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4db2 RCSB], [http://www.ebi.ac.uk/pdbsum/4db2 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			DEAD-box proteins are the largest family of nucleic acid helicases, and are crucial to RNA metabolism throughout all domains of life. They contain a conserved 'helicase core' of two RecA-like domains (domains (D)1 and D2), which uses ATP to catalyse the unwinding of short RNA duplexes by non-processive, local strand separation. This mode of action differs from that of translocating helicases and allows DEAD-box proteins to remodel large RNAs and RNA-protein complexes without globally disrupting RNA structure. However, the structural basis for this distinctive mode of RNA unwinding remains unclear. Here, structural, biochemical and genetic analyses of the yeast DEAD-box protein Mss116p indicate that the helicase core domains have modular functions that enable a novel mechanism for RNA-duplex recognition and unwinding. By investigating D1 and D2 individually and together, we find that D1 acts as an ATP-binding domain and D2 functions as an RNA-duplex recognition domain. D2 contains a nucleic-acid-binding pocket that is formed by conserved DEAD-box protein sequence motifs and accommodates A-form but not B-form duplexes, providing a basis for RNA substrate specificity. Upon a conformational change in which the two core domains join to form a 'closed state' with an ATPase active site, conserved motifs in D1 promote the unwinding of duplex substrates bound to D2 by excluding one RNA strand and bending the other. Our results provide a comprehensive structural model for how DEAD-box proteins recognize and unwind RNA duplexes. This model explains key features of DEAD-box protein function and affords a new perspective on how the evolutionarily related cores of other RNA and DNA helicases diverged to use different mechanisms.

	~~{{STRUCTURE_4db2\| PDB=4db2 \| SCENE= }}~~		Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.,Mallam AL, Del Campo M, Gilman B, Sidote DJ, Lambowitz AM Nature. 2012 Sep 2. doi: 10.1038/nature11402. PMID:22940866<ref>PMID:22940866</ref>

	~~===Mss116p DEAD-box helicase domain 2 bound to an RNA duplex===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22940866}}~~		== References ==
			<references/>
	==~~About this Structure~~==		__TOC__
	~~[[4db2]] is a 10 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].~~		</StructureSection>
	[[Category: RNA helicase]]		[[Category: RNA helicase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Campo, M Del.]]		[[Category: Campo, M Del]]
	[[Category: Gilman, B D.]]		[[Category: Gilman, B D]]
	[[Category: Lambowitz, A.]]		[[Category: Lambowitz, A]]
	[[Category: Mallam, A L.]]		[[Category: Mallam, A L]]
	[[Category: Sidote, D J.]]		[[Category: Sidote, D J]]
	[[Category: Dead-box]]		[[Category: Dead-box]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Rna binding protein-rna complex]]		[[Category: Rna binding protein-rna complex]]
	[[Category: Rna helicase]]		[[Category: Rna helicase]]

OCA at 16:08, 28 November 2012

2012-11-28T16:08:53Z

← Older revision		Revision as of 16:08, 28 November 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[4db2]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].		[[4db2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].
	[[Category: RNA helicase]]		[[Category: RNA helicase]]
			[[Category: Saccharomyces cerevisiae]]
	[[Category: Campo, M Del.]]		[[Category: Campo, M Del.]]
	[[Category: Gilman, B D.]]		[[Category: Gilman, B D.]]

OCA at 06:20, 10 October 2012

2012-10-10T06:20:16Z

← Older revision		Revision as of 06:20, 10 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[4db2]] is a 10 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].		[[4db2]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].
	[[Category: RNA helicase]]		[[Category: RNA helicase]]
	~~[[Category: Saccharomyces cerevisiae]]~~
	[[Category: Campo, M Del.]]		[[Category: Campo, M Del.]]
	[[Category: Gilman, B D.]]		[[Category: Gilman, B D.]]

OCA at 06:22, 19 September 2012

2012-09-19T06:22:17Z

← Older revision		Revision as of 06:22, 19 September 2012
Line 1:		Line 1:
	[[Image:4db2.~~jpg~~\|left\|200px]]		[[Image:4db2.png\|left\|200px]]

	{{STRUCTURE_4db2\| PDB=4db2 \| SCENE= }}		{{STRUCTURE_4db2\| PDB=4db2 \| SCENE= }}
Line 5:		Line 5:
	===Mss116p DEAD-box helicase domain 2 bound to an RNA duplex===		===Mss116p DEAD-box helicase domain 2 bound to an RNA duplex===

			{{ABSTRACT_PUBMED_22940866}}

	==About this Structure==		==About this Structure==

OCA at 05:21, 29 August 2012

2012-08-29T05:21:48Z

← Older revision		Revision as of 05:21, 29 August 2012
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		[[Image:4db2.jpg\|left\|200px]]

	~~The entry~~ 4db2 ~~is ON HOLD~~ ~~until Paper Publication~~		{{STRUCTURE_4db2\| PDB=4db2 \| SCENE= }}

	~~Authors: Mallam, A.L., Del Campo, M., Gilman, B.D., Sidote, D.J., Lambowitz, A.~~		===Mss116p DEAD-box helicase domain 2 bound to an RNA duplex===

	~~Description~~: ~~Mss116p~~/~~substrate 1~~
			==About this Structure==
			[[4db2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DB2 OCA].
			[[Category: RNA helicase]]
			[[Category: Saccharomyces cerevisiae]]
			[[Category: Campo, M Del.]]
			[[Category: Gilman, B D.]]
			[[Category: Lambowitz, A.]]
			[[Category: Mallam, A L.]]
			[[Category: Sidote, D J.]]
			[[Category: Dead-box]]
			[[Category: Hydrolase]]
			[[Category: Rna binding protein-rna complex]]
			[[Category: Rna helicase]]

OCA at 06:09, 14 March 2012

2012-03-14T06:09:18Z

← Older revision		Revision as of 06:09, 14 March 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4db2 is ON HOLD		The entry 4db2 is ON HOLD until Paper Publication

	Authors: Mallam, A.L., Del Campo, M., Gilman, B.D., Sidote, D.J., Lambowitz, A.		Authors: Mallam, A.L., Del Campo, M., Gilman, B.D., Sidote, D.J., Lambowitz, A.

	Description: Mss116p/substrate 1		Description: Mss116p/substrate 1