4dkf - Revision history

OCA at 10:45, 6 November 2024

2024-11-06T10:45:52Z

← Older revision		Revision as of 10:45, 6 November 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DKF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.61Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [https://pdbe.org/4dkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [https://www.ebi.ac.uk/pdbsum/4dkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [https://pdbe.org/4dkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [https://www.ebi.ac.uk/pdbsum/4dkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/IL34_HUMAN IL34_HUMAN]] Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.<ref>PMID:18467591</ref> <ref>PMID:20489731</ref> <ref>PMID:20829061</ref> <ref>PMID:20504948</ref>		[https://www.uniprot.org/uniprot/IL34_HUMAN IL34_HUMAN] Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.<ref>PMID:18467591</ref> <ref>PMID:20489731</ref> <ref>PMID:20829061</ref> <ref>PMID:20504948</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:22, 21 September 2022

2022-09-21T08:22:56Z

← Older revision		Revision as of 08:22, 21 September 2022
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	==Crystal Structure of Human Interleukin-34 Bound to FAb2==		==Crystal Structure of Human Interleukin-34 Bound to FAb2==
	<StructureSection load='4dkf' size='340' side='right' caption='[[4dkf]], [[Resolution\|resolution]] 2.61Å' scene=''>		<StructureSection load='4dkf' size='340' side='right'caption='[[4dkf]], [[Resolution\|resolution]] 2.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4DKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DKF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dkc\|4dkc]], [[4dkd\|4dkd]], [[4dke\|4dke]]</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [https://pdbe.org/4dkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [https://www.ebi.ac.uk/pdbsum/4dkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkf ProSAT]</span></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IL34, C16orf77 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [~~http~~://pdbe.org/4dkf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4dkf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/IL34_HUMAN IL34_HUMAN]] Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.<ref>PMID:18467591</ref> <ref>PMID:20489731</ref> <ref>PMID:20829061</ref> <ref>PMID:20504948</ref>		[[https://www.uniprot.org/uniprot/IL34_HUMAN IL34_HUMAN]] Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.<ref>PMID:18467591</ref> <ref>PMID:20489731</ref> <ref>PMID:20829061</ref> <ref>PMID:20504948</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
	*[[Interleukin\|Interleukin]]		*[[Interleukin 3D structures\|Interleukin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Bazan~~, J F~~]]		[[Category: Large Structures]]
	[[Category: Chen, Y]]		[[Category: Bazan JF]]
	[[Category: Ma, X]]		[[Category: Chen Y]]
	[[Category: Starovasnik~~, M A~~]]		[[Category: Ma X]]
	[[Category: Stawicki, S]]		[[Category: Starovasnik MA]]
	[[Category: Wu, Y]]		[[Category: Stawicki S]]
	~~[[Category: Cytokine-immune system complex]]~~		[[Category: Wu Y]]
	~~[[Category: Dimeric four-helix bundle cytokine]]~~
	~~[[Category: Glycosylation]]~~
	~~[[Category: Igg~~]]

OCA at 13:52, 5 August 2016

2016-08-05T13:52:55Z

← Older revision		Revision as of 13:52, 5 August 2016
Line 1:		Line 1:

	==Crystal Structure of Human Interleukin-34 Bound to FAb2==		==Crystal Structure of Human Interleukin-34 Bound to FAb2==
	<StructureSection load='4dkf' size='340' side='right' caption='[[4dkf]], [[Resolution\|resolution]] 2.61Å' scene=''>		<StructureSection load='4dkf' size='340' side='right' caption='[[4dkf]], [[Resolution\|resolution]] 2.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DKF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DKF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dkc\|4dkc]], [[4dkd\|4dkd]], [[4dke\|4dke]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dkc\|4dkc]], [[4dkd\|4dkd]], [[4dke\|4dke]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IL34, C16orf77 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IL34, C16orf77 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [http://www.ebi.ac.uk/pdbsum/4dkf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [http://pdbe.org/4dkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [http://www.ebi.ac.uk/pdbsum/4dkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4dkf" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Bazan, J F]]		[[Category: Bazan, J F]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]

OCA at 19:20, 25 December 2014

2014-12-25T19:20:48Z

← Older revision		Revision as of 19:20, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [http://www.ebi.ac.uk/pdbsum/4dkf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [http://www.ebi.ac.uk/pdbsum/4dkf PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/IL34_HUMAN IL34_HUMAN]] Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.<ref>PMID:18467591</ref> <ref>PMID:20489731</ref> <ref>PMID:20829061</ref> <ref>PMID:20504948</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:51, 9 December 2014

2014-12-09T15:51:29Z

← Older revision		Revision as of 15:51, 9 December 2014
Line 1:		Line 1:
	[[~~Image~~:~~4dkf~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure of Human Interleukin-34 Bound to FAb2==
			<StructureSection load='4dkf' size='340' side='right' caption='[[4dkf]], [[Resolution\|resolution]] 2.61Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DKF FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4dkc\|4dkc]], [[4dkd\|4dkd]], [[4dke\|4dke]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IL34, C16orf77 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dkf RCSB], [http://www.ebi.ac.uk/pdbsum/4dkf PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Lacking any discernible sequence similarity, interleukin-34 (IL-34) and colony stimulating factor 1 (CSF-1) signal through a common receptor CSF-1R on cells of mononuclear phagocyte lineage. Here, the crystal structure of dimeric IL-34 reveals a helical cytokine fold homologous to CSF-1, and we further show that the complex architecture of IL-34 bound to the N-terminal immunoglobulin domains of CSF-1R is similar to the CSF-1/CSF-1R assembly. However, unique conformational adaptations in the receptor domain geometry and intermolecular interface explain the cross-reactivity of CSF-1R for two such distantly related ligands. The docking adaptations of the IL-34 and CSF-1 quaternary complexes, when compared to the stem cell factor assembly, draw a common evolutionary theme for transmembrane signaling. In addition, the structure of IL-34 engaged by a Fab fragment reveals the mechanism of a neutralizing antibody that can help deconvolute IL-34 from CSF-1 biology, with implications for therapeutic intervention in diseases with myeloid pathogenic mechanisms.

	~~{{STRUCTURE_4dkf\| PDB=4dkf \| SCENE= }}~~		Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.,Ma X, Lin WY, Chen Y, Stawicki S, Mukhyala K, Wu Y, Martin F, Bazan JF, Starovasnik MA Structure. 2012 Apr 4;20(4):676-87. Epub 2012 Apr 3. PMID:22483114<ref>PMID:22483114</ref>

	~~===Crystal Structure~~ of ~~Human Interleukin-34 Bound to FAb2===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22483114}}~~

	~~==About this Structure==~~
	~~[[4dkf]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=4DKF OCA].~~

	==See Also==		==See Also==
	*[[Interleukin\|Interleukin]]		*[[Interleukin\|Interleukin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:022483114<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bazan, J F.]]		[[Category: Bazan, J F]]
	[[Category: Chen, Y.]]		[[Category: Chen, Y]]
	[[Category: Ma, X.]]		[[Category: Ma, X]]
	[[Category: Starovasnik, M A.]]		[[Category: Starovasnik, M A]]
	[[Category: Stawicki, S.]]		[[Category: Stawicki, S]]
	[[Category: Wu, Y.]]		[[Category: Wu, Y]]
	[[Category: Cytokine-immune system complex]]		[[Category: Cytokine-immune system complex]]
	[[Category: Dimeric four-helix bundle cytokine]]		[[Category: Dimeric four-helix bundle cytokine]]
	[[Category: Glycosylation]]		[[Category: Glycosylation]]
	[[Category: Igg]]		[[Category: Igg]]

OCA at 20:29, 20 October 2012

2012-10-20T20:29:04Z

← Older revision		Revision as of 20:29, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[4dkf]] is a 6 chain structure ~~of [[Interleukin]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].		[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].

	==See Also==		==See Also==

OCA at 10:37, 27 July 2012

2012-07-27T10:37:05Z

← Older revision		Revision as of 10:37, 27 July 2012
Line 1:		Line 1:
	[[Image:4dkf.png\|left\|200px]]		[[Image:4dkf.png\|left\|200px]]

	~~<!--~~
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	{{STRUCTURE_4dkf\| PDB=4dkf \| SCENE= }}		{{STRUCTURE_4dkf\| PDB=4dkf \| SCENE= }}

	===Crystal Structure of Human Interleukin-34 Bound to FAb2===		===Crystal Structure of Human Interleukin-34 Bound to FAb2===


	~~<!--~~
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	{{ABSTRACT_PUBMED_22483114}}		{{ABSTRACT_PUBMED_22483114}}

	==About this Structure==		==About this Structure==
	[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].		[[4dkf]] is a 6 chain structure of [[Interleukin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].

			==See Also==
			*[[Interleukin\|Interleukin]]

	==Reference==		==Reference==

OCA at 08:29, 25 April 2012

2012-04-25T08:29:01Z

← Older revision		Revision as of 08:29, 25 April 2012
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	[[Image:4dkf.~~jpg~~\|left\|200px]]		[[Image:4dkf.png\|left\|200px]]

	<!--		<!--
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	===Crystal Structure of Human Interleukin-34 Bound to FAb2===		===Crystal Structure of Human Interleukin-34 Bound to FAb2===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_22483114}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 22483114 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_22483114}}

	==About this Structure==		==About this Structure==
	[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].		[[4dkf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKF OCA].

			==Reference==
			<ref group="xtra">PMID:022483114</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bazan, J F.]]		[[Category: Bazan, J F.]]

OCA at 07:12, 11 April 2012

2012-04-11T07:12:01Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:4dkf.jpg|left|200px]]
-The entry 4dkf is ON HOLD
+<!--
-Authors: Ma, X., Chen, Y., Stawicki, S., Wu, Y., Bazan, J.F., Starovasnik, M.A.
+===Crystal Structure of Human Interleukin-34 Bound to FAb2===
-Description:

OCA: Protected "4dkf" [edit=sysop:move=sysop]

2012-02-15T06:22:11Z

Protected "4dkf" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:22, 15 February 2012
(No difference)