4e15 - Revision history

OCA at 14:49, 14 March 2024

2024-03-14T14:49:29Z

← Older revision		Revision as of 14:49, 14 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E15 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E15 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [https://pdbe.org/4e15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [https://www.ebi.ac.uk/pdbsum/4e15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e15 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [https://pdbe.org/4e15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [https://www.ebi.ac.uk/pdbsum/4e15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/KFA_DROME KFA_DROME]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>		[https://www.uniprot.org/uniprot/KFA_DROME KFA_DROME] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Kynurenine formamidase (KFase), also known as arylformamidase and formylkynurenine formamidase, efficiently catalyzes the hydrolysis of N-formyl-L-kynurenine (NFK) to kynurenine. KFase is the second enzyme in the kynurenine pathway of tryptophan metabolism. A number of intermediates formed in the kynurenine pathway are biologically active and implicated in an assortment of medical conditions, including cancer, schizophrenia and neurodegenerative diseases. Consequently, enzymes involved in the kynurenine pathway have been considered potential regulatory targets. In this study, we report, for the first time, the biochemical characterization and crystal structures of Drosophila melanogaster KFase conjugated with an inhibitor, phenylmethylsulfonyl fluoride (PMSF). The protein architecture of KFase reveals that it belongs to the a/b hydrolase fold family. The PMSF binding information of the solved conjugated crystal structure was used to obtain a KFase and NFK complex using molecular docking. The complex is useful for understanding the catalytic mechanism of KFase. This study provides a molecular basis for future efforts in maintaining or regulating kynurenine metabolism through the molecular and biochemical regulation of KFase.

	~~Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster.,Han Q, Robinson H, Li J Biochem J. 2012 Jun 12. PMID:22690733<ref>PMID:22690733</ref>~~

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4e15" style="background-color:#fffaf0;"></div~~>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:44, 28 September 2022

2022-09-28T06:44:04Z

← Older revision		Revision as of 06:44, 28 September 2022
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	==Crystal structure of kynurenine formamidase conjugated with an inhibitor==		==Crystal structure of kynurenine formamidase conjugated with an inhibitor==
	<StructureSection load='4e15' size='340' side='right' caption='[[4e15]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='4e15' size='340' side='right'caption='[[4e15]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4E15 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E15 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>
	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene~~></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [https://pdbe.org/4e15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [https://www.ebi.ac.uk/pdbsum/4e15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e15 ProSAT]</span></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e11\|4e11]], [[4e14\|4e14]]</td></tr>~~
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG9542, Dmel_CG9542 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arylformamidase Arylformamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.9 3.5.1.9] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [~~http~~://pdbe.org/4e15 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4e15 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4e15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/KFA_DROME KFA_DROME]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>		[[https://www.uniprot.org/uniprot/KFA_DROME KFA_DROME]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Arylformamidase~~]]		[[Category: Drosophila melanogaster]]
	[[Category: ~~Drome~~]]		[[Category: Large Structures]]
	[[Category: Han, Q]]		[[Category: Han Q]]
	[[Category: Li, J]]		[[Category: Li J]]
	[[Category: Robinson, H]]		[[Category: Robinson H]]
	~~[[Category: Alpha/beta hydrolase fold]]~~
	~~[[Category: Hydrolase-hydrolase inhibitor complex~~]]

OCA at 13:28, 11 August 2016

2016-08-11T13:28:39Z

← Older revision		Revision as of 13:28, 11 August 2016
Line 1:		Line 1:

	==Crystal structure of kynurenine formamidase conjugated with an inhibitor==		==Crystal structure of kynurenine formamidase conjugated with an inhibitor==
	<StructureSection load='4e15' size='340' side='right' caption='[[4e15]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='4e15' size='340' side='right' caption='[[4e15]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E15 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E15 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e11\|4e11]], [[4e14\|4e14]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e11\|4e11]], [[4e14\|4e14]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG9542, Dmel_CG9542 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 ~~Drosophila melanogaster~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG9542, Dmel_CG9542 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arylformamidase Arylformamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.9 3.5.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arylformamidase Arylformamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.9 3.5.1.9] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [http://www.ebi.ac.uk/pdbsum/4e15 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [http://pdbe.org/4e15 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [http://www.ebi.ac.uk/pdbsum/4e15 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e15 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~Q9VMC9_DROME Q9VMC9_DROME~~]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>		[[http://www.uniprot.org/uniprot/KFA_DROME KFA_DROME]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 21:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4e15" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Arylformamidase]]		[[Category: Arylformamidase]]
	[[Category: ~~Drosophila melanogaster~~]]		[[Category: Drome]]
	[[Category: Han, Q]]		[[Category: Han, Q]]
	[[Category: Li, J]]		[[Category: Li, J]]

OCA at 13:46, 4 January 2015

2015-01-04T13:46:50Z

← Older revision		Revision as of 13:46, 4 January 2015
Line 1:		Line 1:
	[[~~Image~~:~~4e15~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of kynurenine formamidase conjugated with an inhibitor==
			<StructureSection load='4e15' size='340' side='right' caption='[[4e15]], [[Resolution\|resolution]] 1.50Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4e15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E15 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4e11\|4e11]], [[4e14\|4e14]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG9542, Dmel_CG9542 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arylformamidase Arylformamidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.9 3.5.1.9] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e15 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e15 RCSB], [http://www.ebi.ac.uk/pdbsum/4e15 PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/Q9VMC9_DROME Q9VMC9_DROME]] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Kynurenine formamidase (KFase), also known as arylformamidase and formylkynurenine formamidase, efficiently catalyzes the hydrolysis of N-formyl-L-kynurenine (NFK) to kynurenine. KFase is the second enzyme in the kynurenine pathway of tryptophan metabolism. A number of intermediates formed in the kynurenine pathway are biologically active and implicated in an assortment of medical conditions, including cancer, schizophrenia and neurodegenerative diseases. Consequently, enzymes involved in the kynurenine pathway have been considered potential regulatory targets. In this study, we report, for the first time, the biochemical characterization and crystal structures of Drosophila melanogaster KFase conjugated with an inhibitor, phenylmethylsulfonyl fluoride (PMSF). The protein architecture of KFase reveals that it belongs to the a/b hydrolase fold family. The PMSF binding information of the solved conjugated crystal structure was used to obtain a KFase and NFK complex using molecular docking. The complex is useful for understanding the catalytic mechanism of KFase. This study provides a molecular basis for future efforts in maintaining or regulating kynurenine metabolism through the molecular and biochemical regulation of KFase.

	~~{{STRUCTURE_4e15\| PDB=4e15 \| SCENE= }}~~		Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster.,Han Q, Robinson H, Li J Biochem J. 2012 Jun 12. PMID:22690733<ref>PMID:22690733</ref>

	~~===Crystal structure~~ of ~~kynurenine formamidase conjugated with an inhibitor===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22690733}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[4e15]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Drosophila_melanogaster Drosophila melanogaster]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:022690733<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Arylformamidase]]		[[Category: Arylformamidase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Han, Q.]]		[[Category: Han, Q]]
	[[Category: Li, J.]]		[[Category: Li, J]]
	[[Category: Robinson, H.]]		[[Category: Robinson, H]]
	[[Category: Alpha/beta hydrolase fold]]		[[Category: Alpha/beta hydrolase fold]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 05:37, 29 August 2012

2012-08-29T05:37:52Z

← Older revision		Revision as of 05:37, 29 August 2012
Line 1:		Line 1:
	[[Image:4e15.~~jpg~~\|left\|200px]]		[[Image:4e15.png\|left\|200px]]

	{{STRUCTURE_4e15\| PDB=4e15 \| SCENE= }}		{{STRUCTURE_4e15\| PDB=4e15 \| SCENE= }}

OCA at 05:43, 27 June 2012

2012-06-27T05:43:34Z

← Older revision		Revision as of 05:43, 27 June 2012
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		[[Image:4e15.jpg\|left\|200px]]

	~~The entry~~ 4e15 ~~is ON HOLD~~ ~~until Paper Publication~~		{{STRUCTURE_4e15\| PDB=4e15 \| SCENE= }}

	~~Authors: Han, Q., Robinson, H., Li, J.~~		===Crystal structure of kynurenine formamidase conjugated with an inhibitor===

	~~Description: Crystal~~ structure ~~of kynurenine formamidase conjugated~~ with an inhibitor		{{ABSTRACT_PUBMED_22690733}}

			==About this Structure==
			[[4e15]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E15 OCA].

			==Reference==
			<ref group="xtra">PMID:022690733</ref><references group="xtra"/>
			[[Category: Arylformamidase]]
			[[Category: Drosophila melanogaster]]
			[[Category: Han, Q.]]
			[[Category: Li, J.]]
			[[Category: Robinson, H.]]
			[[Category: Alpha/beta hydrolase fold]]
			[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA: Protected "4e15" [edit=sysop:move=sysop]

2012-03-14T06:15:42Z

Protected "4e15" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:15, 14 March 2012
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OCA: New page: '''Unreleased structure''' The entry 4e15 is ON HOLD until Paper Publication Authors: Han, Q., Robinson, H., Li, J. Description: Crystal structure of kynurenine formamidase conjugated ...

2012-03-14T06:15:41Z

New page: '''Unreleased structure''' The entry 4e15 is ON HOLD until Paper Publication Authors: Han, Q., Robinson, H., Li, J. Description: Crystal structure of kynurenine formamidase conjugated ...

New page

'''Unreleased structure'''

The entry 4e15 is ON HOLD until Paper Publication

Authors: Han, Q., Robinson, H., Li, J.

Description: Crystal structure of kynurenine formamidase conjugated with an inhibitor