4e99 - Revision history

OCA at 13:46, 8 November 2023

2023-11-08T13:46:36Z

← Older revision		Revision as of 13:46, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E99 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E99 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [https://pdbe.org/4e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [https://www.ebi.ac.uk/pdbsum/4e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e99 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [https://pdbe.org/4e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [https://www.ebi.ac.uk/pdbsum/4e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e99 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>		[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>		[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:58, 28 September 2022

2022-09-28T06:58:26Z

← Older revision		Revision as of 06:58, 28 September 2022
Line 1:		Line 1:

	==Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium==		==Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium==
	<StructureSection load='4e99' size='340' side='right' caption='[[4e99]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='4e99' size='340' side='right'caption='[[4e99]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4E99 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E99 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [https://pdbe.org/4e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [https://www.ebi.ac.uk/pdbsum/4e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e99 ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [~~http~~://pdbe.org/4e99 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4e99 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4e99 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[[~~http~~://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[~~http~~://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>		[[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>		[[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:

	==See Also==		==See Also==
	*[[Albumin\|Albumin]]		*[[Albumin 3D structures\|Albumin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: ~~Huang, M D~~]]		[[Category: Large Structures]]
	[[Category: ~~Luo, Z P~~]]		[[Category: Huang MD]]
	[[Category: ~~Shi, X L~~]]		[[Category: Luo ZP]]
	[[Category: ~~Drug binding]]~~		[[Category: Shi XL]]
	~~[[Category: Extracellular]]~~
	~~[[Category: Plasma protein]]~~
	~~[[Category: Transport protein]]~~
	~~[[Category: Transporter~~]]

OCA at 07:36, 4 August 2016

2016-08-04T07:36:52Z

← Older revision		Revision as of 07:36, 4 August 2016
Line 1:		Line 1:

	==Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium==		==Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium==
	<StructureSection load='4e99' size='340' side='right' caption='[[4e99]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='4e99' size='340' side='right' caption='[[4e99]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E99 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E99 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [http://www.ebi.ac.uk/pdbsum/4e99 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [http://pdbe.org/4e99 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [http://www.ebi.ac.uk/pdbsum/4e99 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e99 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4e99" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Huang, M D]]		[[Category: Huang, M D]]
	[[Category: Luo, Z P]]		[[Category: Luo, Z P]]

OCA at 11:02, 21 December 2014

2014-12-21T11:02:41Z

← Older revision		Revision as of 11:02, 21 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_4e99~~\| ~~PDB~~=4e99 \| ~~SCENE~~= }}		==Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium==
	===~~Human~~ Serum ~~Albumin Complex with Perfluorooctane Sulfonate Potassium~~===		<StructureSection load='4e99' size='340' side='right' caption='[[4e99]], [[Resolution\|resolution]] 2.30Å' scene=''>
	~~{{ABSTRACT_PUBMED_22482699}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E99 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P8S:HEPTADECAFLUORO-1-OCTANESULFONIC+ACID'>P8S</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e99 RCSB], [http://www.ebi.ac.uk/pdbsum/4e99 PDBsum]</span></td></tr>
			</table>
			== Disease ==
			[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
			== Function ==
			[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Perfluorooctane sulfonate (PFOS) is a man-made fluorosurfactant and globally persistent organic pollutant. PFOS is mainly distributed in blood with a long half-life for elimination. PFOS was found mainly bound to human serum albumin (HSA) in plasma, the most abundant protein in human blood plasma, which transports a variety of endogenous and exogenous ligands. However, the structural basis of such binding remains unclear. Here, we report the crystal structure of the HSA-PFOS complex and show that PFOS binds to HSA at a molar ratio of 2:1. In addition, PFOS binding renders the HSA structure more compact. Our results provide a structural mechanism to understand the retention of surfactants in human serum.

	~~==Disease==~~		Structural evidence of perfluorooctane sulfonate transport by human serum albumin.,Luo Z, Shi X, Hu Q, Zhao B, Huang M Chem Res Toxicol. 2012 May 21;25(5):990-2. Epub 2012 Apr 16. PMID:22482699<ref>PMID:22482699</ref>
	~~[[http://www~~.~~uniprot~~.~~org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia~~ (~~FDH~~) ~~[MIM~~:~~[http://omim~~.~~org/entry/103600 103600]]~~. ~~FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>~~PMID:~~8048949</ref><ref>PMID:7852505</ref><ref>PMID:9329347</ref>~~<ref>PMID:~~9589637~~</ref>

	~~==Function==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[http://www.uniprot.org/uniprot~~/~~ALBU_HUMAN ALBU_HUMAN]] Serum albumin~~, ~~the main protein of plasma, has~~ a ~~good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation~~ of the ~~colloidal osmotic pressure of blood~~. ~~Major zinc transporter in plasma, typically binds about 80%~~ of ~~all plasma zinc~~.<~~ref~~>~~PMID:19021548~~</~~ref~~>		</div>

	~~==About this Structure==~~
	[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA].

	==See Also==		==See Also==
	*[[Albumin\|Albumin]]		*[[Albumin\|Albumin]]
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:022482699</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Huang, M D.]]		[[Category: Huang, M D]]
	[[Category: Luo, Z P.]]		[[Category: Luo, Z P]]
	[[Category: Shi, X L.]]		[[Category: Shi, X L]]
	[[Category: Drug binding]]		[[Category: Drug binding]]
	[[Category: Extracellular]]		[[Category: Extracellular]]

OCA at 09:21, 24 March 2013

2013-03-24T09:21:00Z

← Older revision		Revision as of 09:21, 24 March 2013
Line 1:		Line 1:
	~~[[Image:4e99.jpg\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_4e99", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_4e99\| PDB=4e99 \| SCENE= }}		{{STRUCTURE_4e99\| PDB=4e99 \| SCENE= }}

	===Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium===		===Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium===
			{{ABSTRACT_PUBMED_22482699}}

			==Disease==
			[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref><ref>PMID:7852505</ref><ref>PMID:9329347</ref><ref>PMID:9589637</ref>

	~~<!--~~		==Function==
	~~The line below this paragraph, {{ABSTRACT_PUBMED_22482699}}, adds the Publication Abstract to the page~~		[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~), ~~where 22482699~~ is the ~~PubMed ID number~~.
	-->
	~~{{ABSTRACT_PUBMED_22482699}}~~

	==About this Structure==		==About this Structure==
	[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA].		[[4e99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E99 OCA].

			==See Also==
			*[[Albumin\|Albumin]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:022482699</ref><references group="xtra"/>		<ref group="xtra">PMID:022482699</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Huang, M D.]]		[[Category: Huang, M D.]]

OCA at 07:39, 6 June 2012

2012-06-06T07:39:16Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:4e99.jpg|left|200px]]
-The entry 4e99 is ON HOLD  until Paper Publication
+<!--
-Authors: Huang, M.D., Luo, Z.P., Shi, X.L.
+===Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium===
-Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium

OCA at 06:39, 11 April 2012

2012-04-11T06:39:47Z

← Older revision		Revision as of 06:39, 11 April 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4e99 is ON HOLD		The entry 4e99 is ON HOLD until Paper Publication

	Authors: Huang, M.D., Luo, Z.P., Shi, X.L.		Authors: Huang, M.D., Luo, Z.P., Shi, X.L.

	Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium		Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium

OCA: Protected "4e99" [edit=sysop:move=sysop]

2012-03-28T07:25:22Z

Protected "4e99" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:25, 28 March 2012
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4e99 is ON HOLD Authors: Huang, M.D., Luo, Z.P., Shi, X.L. Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium

2012-03-28T07:25:21Z

New page: '''Unreleased structure''' The entry 4e99 is ON HOLD Authors: Huang, M.D., Luo, Z.P., Shi, X.L. Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium

New page

'''Unreleased structure'''

The entry 4e99 is ON HOLD

Authors: Huang, M.D., Luo, Z.P., Shi, X.L.

Description: Human Serum Albumin Complex with Perfluorooctane Sulfonate Potassium