4eab - Revision history

OCA at 14:56, 14 March 2024

2024-03-14T14:56:42Z

← Older revision		Revision as of 14:56, 14 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [https://pdbe.org/4eab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [https://www.ebi.ac.uk/pdbsum/4eab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eab ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [https://pdbe.org/4eab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [https://www.ebi.ac.uk/pdbsum/4eab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eab ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/O85353_CAUVI O85353_CAUVI]]		[https://www.uniprot.org/uniprot/O85353_CAUVI O85353_CAUVI]
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	N-acetylperosamine is an unusual dideoxysugar found in the O-antigens of some Gram-negative bacteria including the pathogenic Escherichia coli strain O157:H7. The last step in its biosynthesis is catalyzed by PerB, an N-acetyltransferase belonging to the left-handed beta-helix superfamily of proteins. Here we describe a combined structural and functional investigation on PerB from Caulobacter crescentus. For this study, three structures were determined to 1.0 A resolution or better: the enzyme in complex with CoA and GDP-perosamine, the protein with bound CoA and GDP-N-acetylperosamine, and the enzyme containing a tetrahedral transition state mimic bound in the active site. Each subunit of the trimeric enzyme folds into two distinct regions. The N-terminal domain is globular and dominated by a six-stranded mainly parallel beta-sheet. It provides most of the interactions between the protein and GDP-perosamine. The C-terminal domain consists of a left-handed beta-helix, which has nearly seven turns. This region provides the scaffold for CoA binding. On the basis of these high-resolution structures, site-directed mutant proteins were constructed to test the roles of His 141 and Asp 142 in the catalytic mechanism. Kinetic data and pH rate profiles are indicative of His 141 serving as a general base. In addition, the backbone amide group of Gly 159 provides an oxyanion hole for stabilization of the tetrahedral transition state. The pH rate profiles are also consistent with the GDP-linked amino sugar substrate entering the active site in its unprotonated form. Finally, for this investigation, we show that PerB can accept GDP-3-deoxyperosamine as an alternative substrate, thus representing the production of a novel trideoxysugar.

	The Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High Resolution X-ray Crystallographic Studies and Kinetic Analyses.,Thoden JB, Reinhardt LA, Cook PD, Menden P, Cleland WW, Holden HM Biochemistry. 2012 Mar 23. PMID:22443398<ref>PMID:22443398</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4eab" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:00, 28 September 2022

2022-09-28T07:00:01Z

← Older revision		Revision as of 07:00, 28 September 2022
Line 1:		Line 1:

	==X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine==		==X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine==
	<StructureSection load='4eab' size='340' side='right' caption='[[4eab]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='4eab' size='340' side='right'caption='[[4eab]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cauce Cauce~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4EAB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ea7\|4ea7]], [[4ea8\|4ea8]], [[4ea9\|4ea9]], [[4eaa\|4eaa]]</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [https://pdbe.org/4eab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [https://www.ebi.ac.uk/pdbsum/4eab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eab ProSAT]</span></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_1011, wbqR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 CAUCE])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [~~http~~://pdbe.org/4eab PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4eab PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4eab ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[[https://www.uniprot.org/uniprot/O85353_CAUVI O85353_CAUVI]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Cauce~~]]		[[Category: Caulobacter vibrioides]]
	[[Category: Cleland~~, W W~~]]		[[Category: Large Structures]]
	[[Category: Cook~~, P D~~]]		[[Category: Cleland WW]]
	[[Category: Holden~~, H M~~]]		[[Category: Cook PD]]
	[[Category: Menden, P]]		[[Category: Holden HM]]
	[[Category: Reinhardt~~, L A~~]]		[[Category: Menden P]]
	[[Category: Thoden~~, J B]]~~		[[Category: Reinhardt LA]]
	~~[[Category: Acetyl coenzyme some]]~~		[[Category: Thoden JB]]
	~~[[Category: Acetyltransferase]]~~
	~~[[Category: Beta helix]]~~
	~~[[Category: Gdp-perosamine]]~~
	~~[[Category: Transferase~~]]

OCA at 19:00, 11 August 2016

2016-08-11T19:00:39Z

← Older revision		Revision as of 19:00, 11 August 2016
Line 1:		Line 1:

	==X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine==		==X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine==
	<StructureSection load='4eab' size='340' side='right' caption='[[4eab]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='4eab' size='340' side='right' caption='[[4eab]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Caulobacter_vibrioides Caulobacter vibrioides~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cauce Cauce]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ea7\|4ea7]], [[4ea8\|4ea8]], [[4ea9\|4ea9]], [[4eaa\|4eaa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ea7\|4ea7]], [[4ea8\|4ea8]], [[4ea9\|4ea9]], [[4eaa\|4eaa]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_1011, wbqR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ~~Caulobacter vibrioides~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_1011, wbqR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 CAUCE])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [http://www.ebi.ac.uk/pdbsum/4eab PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [http://pdbe.org/4eab PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [http://www.ebi.ac.uk/pdbsum/4eab PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eab ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4eab" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Caulobacter vibrioides~~]]		[[Category: Cauce]]
	[[Category: Cleland, W W]]		[[Category: Cleland, W W]]
	[[Category: Cook, P D]]		[[Category: Cook, P D]]

OCA at 13:58, 4 January 2015

2015-01-04T13:58:57Z

← Older revision		Revision as of 13:58, 4 January 2015
Line 1:		Line 1:
	[[~~Image~~:~~4eab~~.~~png~~\|~~left~~\|~~200px~~]]		==X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine==
			<StructureSection load='4eab' size='340' side='right' caption='[[4eab]], [[Resolution\|resolution]] 1.35Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4eab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAB FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=JB2:GDP-PEROSAMINE'>JB2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ea7\|4ea7]], [[4ea8\|4ea8]], [[4ea9\|4ea9]], [[4eaa\|4eaa]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_1011, wbqR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 Caulobacter vibrioides])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eab OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eab RCSB], [http://www.ebi.ac.uk/pdbsum/4eab PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			N-acetylperosamine is an unusual dideoxysugar found in the O-antigens of some Gram-negative bacteria including the pathogenic Escherichia coli strain O157:H7. The last step in its biosynthesis is catalyzed by PerB, an N-acetyltransferase belonging to the left-handed beta-helix superfamily of proteins. Here we describe a combined structural and functional investigation on PerB from Caulobacter crescentus. For this study, three structures were determined to 1.0 A resolution or better: the enzyme in complex with CoA and GDP-perosamine, the protein with bound CoA and GDP-N-acetylperosamine, and the enzyme containing a tetrahedral transition state mimic bound in the active site. Each subunit of the trimeric enzyme folds into two distinct regions. The N-terminal domain is globular and dominated by a six-stranded mainly parallel beta-sheet. It provides most of the interactions between the protein and GDP-perosamine. The C-terminal domain consists of a left-handed beta-helix, which has nearly seven turns. This region provides the scaffold for CoA binding. On the basis of these high-resolution structures, site-directed mutant proteins were constructed to test the roles of His 141 and Asp 142 in the catalytic mechanism. Kinetic data and pH rate profiles are indicative of His 141 serving as a general base. In addition, the backbone amide group of Gly 159 provides an oxyanion hole for stabilization of the tetrahedral transition state. The pH rate profiles are also consistent with the GDP-linked amino sugar substrate entering the active site in its unprotonated form. Finally, for this investigation, we show that PerB can accept GDP-3-deoxyperosamine as an alternative substrate, thus representing the production of a novel trideoxysugar.

	~~{{STRUCTURE_4eab\| PDB=4eab \| SCENE= }}~~		The Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High Resolution X-ray Crystallographic Studies and Kinetic Analyses.,Thoden JB, Reinhardt LA, Cook PD, Menden P, Cleland WW, Holden HM Biochemistry. 2012 Mar 23. PMID:22443398<ref>PMID:22443398</ref>

	~~===X-ray crystal structure~~ of the ~~H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22443398}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[4eab]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:022443398<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
	[[Category: Cleland, W W.]]		[[Category: Cleland, W W]]
	[[Category: Cook, P D.]]		[[Category: Cook, P D]]
	[[Category: Holden, H M.]]		[[Category: Holden, H M]]
	[[Category: Menden, P.]]		[[Category: Menden, P]]
	[[Category: Reinhardt, L A.]]		[[Category: Reinhardt, L A]]
	[[Category: Thoden, J B.]]		[[Category: Thoden, J B]]
	[[Category: Acetyl coenzyme some]]		[[Category: Acetyl coenzyme some]]
	[[Category: Acetyltransferase]]		[[Category: Acetyltransferase]]

OCA at 08:20, 2 January 2013

2013-01-02T08:20:56Z

← Older revision		Revision as of 08:20, 2 January 2013
Line 1:		Line 1:
	[[Image:4eab.png\|left\|200px]]		[[Image:4eab.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_4eab", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_4eab\| PDB=4eab \| SCENE= }}		{{STRUCTURE_4eab\| PDB=4eab \| SCENE= }}

	===X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===		===X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_22443398}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 22443398 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_22443398}}		{{ABSTRACT_PUBMED_22443398}}

OCA at 06:16, 11 April 2012

2012-04-11T06:16:46Z

← Older revision		Revision as of 06:16, 11 April 2012
Line 1:		Line 1:
	[[Image:4eab.~~jpg~~\|left\|200px]]		[[Image:4eab.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===		===X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_22443398}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 22443398 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_22443398}}

	==About this Structure==		==About this Structure==
	[[4eab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA].		[[4eab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAB OCA].

			==Reference==
			<ref group="xtra">PMID:022443398</ref><references group="xtra"/>
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
	[[Category: Cleland, W W.]]		[[Category: Cleland, W W.]]

OCA at 06:22, 4 April 2012

2012-04-04T06:22:06Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:4eab.jpg|left|200px]]
-The entry 4eab is ON HOLD
+<!--
-Authors: thoden, J.B., reinhardt, L.A., , cook, P.D., menden, P., cleland, W.W., holden, H.M.
+===X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine===
-Description: x-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from caulobacter crescentus in complex with CoA and GDP-perosamine

OCA: Protected "4eab" [edit=sysop:move=sysop]

2012-03-28T07:26:32Z

Protected "4eab" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:26, 28 March 2012
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4eab is ON HOLD Authors: thoden, J.B., reinhardt, L.A., , cook, P.D., menden, P., cleland, W.W., holden, H.M. Description: x-ray crystal structure ...

2012-03-28T07:26:31Z

New page: '''Unreleased structure''' The entry 4eab is ON HOLD Authors: thoden, J.B., reinhardt, L.A., , cook, P.D., menden, P., cleland, W.W., holden, H.M. Description: x-ray crystal structure ...

New page

'''Unreleased structure'''

The entry 4eab is ON HOLD

Authors: thoden, J.B., reinhardt, L.A., , cook, P.D., menden, P., cleland, W.W., holden, H.M.

Description: x-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from caulobacter crescentus in complex with CoA and GDP-perosamine