4eex - Revision history

OCA at 11:03, 1 March 2024

2024-03-01T11:03:28Z

← Older revision		Revision as of 11:03, 1 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_KF147 Lactococcus lactis subsp. lactis KF147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EEX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_KF147 Lactococcus lactis subsp. lactis KF147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EEX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [https://pdbe.org/4eex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [https://www.ebi.ac.uk/pdbsum/4eex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eex ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [https://pdbe.org/4eex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [https://www.ebi.ac.uk/pdbsum/4eex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eex ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/D2BLA0_LACLK D2BLA0_LACLK]]		[https://www.uniprot.org/uniprot/D2BLA0_LACLK D2BLA0_LACLK]
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	We have determined the X-ray crystal structures of the NADH-dependent alcohol dehydrogenase LlAdhA from Lactococcus lactis and its laboratory-evolved variant LlAdhA(RE1) at 1.9A and 2.5A resolution, respectively. LlAdhA(RE1), which contains three amino acid mutations (Y50F, I212T, and L264V), was engineered to increase the microbial production of isobutanol (2-methylpropan-1-ol) from isobutyraldehyde (2-methylpropanal). Structural comparison of LlAdhA and LlAdhA(RE1) indicates that the enhanced activity on isobutyraldehyde stems from increases in the protein's active site size, hydrophobicity, and substrate access. Further structure-guided mutagenesis generated a quadruple mutant (Y50F/N110S/I212T/L264V), whose K(M) for isobutyraldehyde is approximately 17-fold lower and catalytic efficiency (k(cat)/K(M)) is approximately 160-fold higher than wild-type LlAdhA. Combining detailed structural information and directed evolution, we have achieved significant improvements in non-native alcohol dehydrogenase activity that will facilitate the production of next-generation fuels such as isobutanol from renewable resources.

	Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.,Liu X, Bastian S, Snow CD, Brustad EM, Saleski TE, Xu JH, Meinhold P, Arnold FH J Biotechnol. 2012 Sep 3. pii: S0168-1656(12)00610-4. doi:, 10.1016/j.jbiotec.2012.08.008. PMID:22974724<ref>PMID:22974724</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>~~

	==See Also==		==See Also==
	*[[Alcohol dehydrogenase 3D structures\|Alcohol dehydrogenase 3D structures]]		*[[Alcohol dehydrogenase 3D structures\|Alcohol dehydrogenase 3D structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:08, 28 September 2022

2022-09-28T07:08:13Z

← Older revision		Revision as of 07:08, 28 September 2022
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	==Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase==		==Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase==
	<StructureSection load='4eex' size='340' side='right' caption='[[4eex]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4eex' size='340' side='right'caption='[[4eex]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Laclk Laclk~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4EEX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_KF147 Lactococcus lactis subsp. lactis KF147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EEX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4eez\|4eez]]</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [https://pdbe.org/4eex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [https://www.ebi.ac.uk/pdbsum/4eex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eex ProSAT]</span></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">adhA, LLKF_1981 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=684738 LACLK])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [~~http~~://pdbe.org/4eex PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4eex PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4eex ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[[https://www.uniprot.org/uniprot/D2BLA0_LACLK D2BLA0_LACLK]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Alcohol dehydrogenase 3D structures\|Alcohol dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Alcohol dehydrogenase~~]]		[[Category: Lactococcus lactis subsp. lactis KF147]]
	[[Category: ~~Laclk~~]]		[[Category: Large Structures]]
	[[Category: Arnold~~, F H~~]]		[[Category: Arnold FH]]
	[[Category: Bastian, S]]		[[Category: Bastian S]]
	[[Category: Brustad~~, E M~~]]		[[Category: Brustad EM]]
	[[Category: Liu, X]]		[[Category: Liu X]]
	[[Category: Meinhold, P]]		[[Category: Meinhold P]]
	[[Category: Saleski, T]]		[[Category: Saleski T]]
	[[Category: Snow~~, C D~~]]		[[Category: Snow CD]]
	[[Category: Xu~~, J H]]~~		[[Category: Xu JH]]
	~~[[Category: Biofuel]]~~
	~~[[Category: Directed evolution]]~~
	~~[[Category: Isobutyraldehyde]]~~
	~~[[Category: Oxidoreductase]]~~
	~~[[Category: Site-saturation mutagenesis~~]]

OCA at 19:53, 24 January 2018

2018-01-24T19:53:21Z

← Older revision		Revision as of 19:53, 24 January 2018
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:59, 11 August 2016

2016-08-11T07:59:12Z

← Older revision		Revision as of 07:59, 11 August 2016
Line 1:		Line 1:

	==Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase==		==Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase==
	<StructureSection load='4eex' size='340' side='right' caption='[[4eex]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4eex' size='340' side='right' caption='[[4eex]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lactococcus_lactis_subsp._lactis_kf147 Lactococcus lactis subsp. lactis kf147~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EEX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Laclk Laclk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EEX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4eez\|4eez]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4eez\|4eez]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">adhA, LLKF_1981 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=684738 ~~Lactococcus lactis subsp. lactis KF147~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">adhA, LLKF_1981 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=684738 LACLK])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [http://www.ebi.ac.uk/pdbsum/4eex PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [http://pdbe.org/4eex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [http://www.ebi.ac.uk/pdbsum/4eex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eex ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4eex" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Alcohol dehydrogenase]]		[[Category: Alcohol dehydrogenase]]
	[[Category: ~~Lactococcus lactis subsp. lactis kf147~~]]		[[Category: Laclk]]
	[[Category: Arnold, F H]]		[[Category: Arnold, F H]]
	[[Category: Bastian, S]]		[[Category: Bastian, S]]

OCA at 13:08, 5 January 2015

2015-01-05T13:08:45Z

← Older revision		Revision as of 13:08, 5 January 2015
Line 1:		Line 1:
	[[~~Image~~:~~4eex~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase==
			<StructureSection load='4eex' size='340' side='right' caption='[[4eex]], [[Resolution\|resolution]] 2.20Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4eex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_kf147 Lactococcus lactis subsp. lactis kf147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EEX FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4eez\|4eez]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">adhA, LLKF_1981 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=684738 Lactococcus lactis subsp. lactis KF147])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eex OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eex RCSB], [http://www.ebi.ac.uk/pdbsum/4eex PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			We have determined the X-ray crystal structures of the NADH-dependent alcohol dehydrogenase LlAdhA from Lactococcus lactis and its laboratory-evolved variant LlAdhA(RE1) at 1.9A and 2.5A resolution, respectively. LlAdhA(RE1), which contains three amino acid mutations (Y50F, I212T, and L264V), was engineered to increase the microbial production of isobutanol (2-methylpropan-1-ol) from isobutyraldehyde (2-methylpropanal). Structural comparison of LlAdhA and LlAdhA(RE1) indicates that the enhanced activity on isobutyraldehyde stems from increases in the protein's active site size, hydrophobicity, and substrate access. Further structure-guided mutagenesis generated a quadruple mutant (Y50F/N110S/I212T/L264V), whose K(M) for isobutyraldehyde is approximately 17-fold lower and catalytic efficiency (k(cat)/K(M)) is approximately 160-fold higher than wild-type LlAdhA. Combining detailed structural information and directed evolution, we have achieved significant improvements in non-native alcohol dehydrogenase activity that will facilitate the production of next-generation fuels such as isobutanol from renewable resources.

	~~{{STRUCTURE_4eex\| PDB=4eex \| SCENE= }}~~		Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.,Liu X, Bastian S, Snow CD, Brustad EM, Saleski TE, Xu JH, Meinhold P, Arnold FH J Biotechnol. 2012 Sep 3. pii: S0168-1656(12)00610-4. doi:, 10.1016/j.jbiotec.2012.08.008. PMID:22974724<ref>PMID:22974724</ref>

	~~===Crystal Structure~~ of ~~Lactococcus lactis Alcohol Dehydrogenase===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_22974724}}~~		==See Also==
			*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]
	==~~About this Structure~~==		== References ==
	[[~~4eex~~]] ~~is a 2 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_kf147 Lactococcus lactis subsp. lactis kf147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA].		<references/>
			__TOC__
			</StructureSection>
	[[Category: Alcohol dehydrogenase]]		[[Category: Alcohol dehydrogenase]]
	[[Category: Lactococcus lactis subsp. lactis kf147]]		[[Category: Lactococcus lactis subsp. lactis kf147]]
	[[Category: Arnold, F H.]]		[[Category: Arnold, F H]]
	[[Category: Bastian, S.]]		[[Category: Bastian, S]]
	[[Category: Brustad, E M.]]		[[Category: Brustad, E M]]
	[[Category: Liu, X.]]		[[Category: Liu, X]]
	[[Category: Meinhold, P.]]		[[Category: Meinhold, P]]
	[[Category: Saleski, T]]		[[Category: Saleski, T]]
	[[Category: Snow, C D.]]		[[Category: Snow, C D]]
	[[Category: Xu, J H~~.]]~~		[[Category: Xu, J H]]
	~~[[Category: Alcohol dehydrogenase~~]]
	[[Category: Biofuel]]		[[Category: Biofuel]]
	[[Category: Directed evolution]]		[[Category: Directed evolution]]

OCA at 09:55, 21 November 2012

2012-11-21T09:55:34Z

← Older revision		Revision as of 09:55, 21 November 2012
Line 1:		Line 1:
	[[Image:4eex.~~jpg~~\|left\|200px]]		[[Image:4eex.png\|left\|200px]]

	{{STRUCTURE_4eex\| PDB=4eex \| SCENE= }}		{{STRUCTURE_4eex\| PDB=4eex \| SCENE= }}
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[4eex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis_subsp.~~_lactis~~ Lactococcus lactis subsp. lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA].		[[4eex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_kf147 Lactococcus lactis subsp. lactis kf147]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEX OCA].
	[[Category: Alcohol dehydrogenase]]		[[Category: Alcohol dehydrogenase]]
	[[Category: Lactococcus lactis subsp. lactis]]		[[Category: Lactococcus lactis subsp. lactis kf147]]
	[[Category: Arnold, F H.]]		[[Category: Arnold, F H.]]
	[[Category: Bastian, S.]]		[[Category: Bastian, S.]]

OCA at 20:34, 26 September 2012

2012-09-26T20:34:48Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:4eex.jpg|left|200px]]
-The entry 4eex is ON HOLD  until Paper Publication
+{{STRUCTURE_4eex|  PDB=4eex  |  SCENE=  }}
-Authors: Liu, X., Bastian, S., Snow, C.D., Brustad, E.M., Saleski, T, Xu, J.H., Meinhold, P., Arnold, F.H.
+===Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase===
-Description: Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase
+{{ABSTRACT_PUBMED_22974724}}

OCA at 06:41, 11 April 2012

2012-04-11T06:41:25Z

← Older revision		Revision as of 06:41, 11 April 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4eex is ON HOLD		The entry 4eex is ON HOLD until Paper Publication

	Authors: ~~Xiang~~ Liu, ~~Sabine~~ Bastian, ~~Christopher~~ D. ~~Snow~~, ~~Eric~~ M. ~~Brustad~~, ~~Tatyana~~ Saleski, ~~Jian-He~~ Xu, ~~Peter~~ Meinhold, ~~Frances~~ H. ~~Arnold~~		Authors: Liu, X., Bastian, S., Snow, C.D., Brustad, E.M., Saleski, T, Xu, J.H., Meinhold, P., Arnold, F.H.

	Description: Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase		Description: Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase

OCA: Protected "4eex" [edit=sysop:move=sysop]

2012-04-04T05:51:00Z

Protected "4eex" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:51, 4 April 2012
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4eex is ON HOLD Authors: Xiang Liu, Sabine Bastian, Christopher D. Snow, Eric M. Brustad, Tatyana Saleski, Jian-He Xu, Peter Meinhold, Frances H. Ar...

2012-04-04T05:50:59Z

New page: '''Unreleased structure''' The entry 4eex is ON HOLD Authors: Xiang Liu, Sabine Bastian, Christopher D. Snow, Eric M. Brustad, Tatyana Saleski, Jian-He Xu, Peter Meinhold, Frances H. Ar...

New page

'''Unreleased structure'''

The entry 4eex is ON HOLD

Authors: Xiang Liu, Sabine Bastian, Christopher D. Snow, Eric M. Brustad, Tatyana Saleski, Jian-He Xu, Peter Meinhold, Frances H. Arnold

Description: Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase