4eo2 - Revision history

OCA at 11:04, 1 March 2024

2024-03-01T11:04:25Z

← Older revision		Revision as of 11:04, 1 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eo2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_virus_C1 Streptococcus virus C1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EO2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eo2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_virus_C1 Streptococcus virus C1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EO2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [https://pdbe.org/4eo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4eo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eo2 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.007Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [https://pdbe.org/4eo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4eo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eo2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/Q7Y3F0_9CAUD Q7Y3F0_9CAUD]]		[https://www.uniprot.org/uniprot/Q7Y3F0_9CAUD Q7Y3F0_9CAUD]
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The Podoviridae phage C1 was one of the earliest isolated bacteriophages and the first virus documented to be active against streptococci. The icosahedral and asymmetric reconstructions of the virus were calculated using cryo-electron microscopy. The capsid protein has an HK97 fold arranged into a T = 4 icosahedral lattice. The C1 tail is terminated with a varphi29-like knob, surrounded by a skirt of twelve long appendages with novel morphology. Several C1 structural proteins have been identified, including a candidate for an appendage. The crystal structure of the knob has an N-terminal domain with a fold observed previously in tube forming proteins of Siphoviridae and Myoviridae phages. The structure of C1 suggests the mechanisms by which the virus digests the cell wall and ejects its genome. Although there is little sequence similarity to other phages, conservation of the structural proteins demonstrates a common origin of the head and tail, but more recent evolution of the appendages.

	Structural investigations of a Podoviridae streptococcus phage C1, implications for the mechanism of viral entry.,Aksyuk AA, Bowman VD, Kaufmann B, Fields C, Klose T, Holdaway HA, Fischetti VA, Rossmann MG Proc Natl Acad Sci U S A. 2012 Aug 13. PMID:22891295<ref>PMID:22891295</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4eo2" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:20, 28 September 2022

2022-09-28T07:20:12Z

← Older revision		Revision as of 07:20, 28 September 2022
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	==Structure of the bacteriophage C1 tail knob protein, gp12==		==Structure of the bacteriophage C1 tail knob protein, gp12==
	<StructureSection load='4eo2' size='340' side='right' caption='[[4eo2]], [[Resolution\|resolution]] 3.01Å' scene=''>		<StructureSection load='4eo2' size='340' side='right'caption='[[4eo2]], [[Resolution\|resolution]] 3.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4eo2]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Streptococcus_phage_c1~~ Streptococcus ~~phage c1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4EO2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4eo2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_virus_C1 Streptococcus virus C1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EO2 FirstGlance]. <br>
	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ep0\|4ep0]]</td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [https://pdbe.org/4eo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4eo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eo2 ProSAT]</span></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">orf12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=230871 Streptococcus phage C1])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [~~http~~://pdbe.org/4eo2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4eo2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4eo2 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[[https://www.uniprot.org/uniprot/Q7Y3F0_9CAUD Q7Y3F0_9CAUD]]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Streptococcus phage c1~~]]		[[Category: Large Structures]]
	[[Category: ~~Aksyuk, A A~~]]		[[Category: Streptococcus virus C1]]
	[[Category: ~~Rossmann, M G~~]]		[[Category: Aksyuk AA]]
	[[Category: ~~Structural protein]]~~		[[Category: Rossmann MG]]
	~~[[Category: Viral protein~~]]

OCA at 10:35, 11 August 2016

2016-08-11T10:35:57Z

← Older revision		Revision as of 10:35, 11 August 2016
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	==Structure of the bacteriophage C1 tail knob protein, gp12==		==Structure of the bacteriophage C1 tail knob protein, gp12==
	<StructureSection load='4eo2' size='340' side='right' caption='[[4eo2]], [[Resolution\|resolution]] 3.01Å' scene=''>		<StructureSection load='4eo2' size='340' side='right' caption='[[4eo2]], [[Resolution\|resolution]] 3.01Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ep0\|4ep0]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ep0\|4ep0]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">orf12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=230871 Streptococcus phage C1])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">orf12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=230871 Streptococcus phage C1])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4eo2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [http://pdbe.org/4eo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4eo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eo2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4eo2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:28, 4 January 2015

2015-01-04T14:28:45Z

← Older revision		Revision as of 14:28, 4 January 2015
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	[[~~Image~~:~~4eo2~~.~~png~~\|~~left~~\|~~200px~~]]		==Structure of the bacteriophage C1 tail knob protein, gp12==
			<StructureSection load='4eo2' size='340' side='right' caption='[[4eo2]], [[Resolution\|resolution]] 3.01Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4eo2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_c1 Streptococcus phage c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EO2 FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ep0\|4ep0]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">orf12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=230871 Streptococcus phage C1])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eo2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4eo2 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The Podoviridae phage C1 was one of the earliest isolated bacteriophages and the first virus documented to be active against streptococci. The icosahedral and asymmetric reconstructions of the virus were calculated using cryo-electron microscopy. The capsid protein has an HK97 fold arranged into a T = 4 icosahedral lattice. The C1 tail is terminated with a varphi29-like knob, surrounded by a skirt of twelve long appendages with novel morphology. Several C1 structural proteins have been identified, including a candidate for an appendage. The crystal structure of the knob has an N-terminal domain with a fold observed previously in tube forming proteins of Siphoviridae and Myoviridae phages. The structure of C1 suggests the mechanisms by which the virus digests the cell wall and ejects its genome. Although there is little sequence similarity to other phages, conservation of the structural proteins demonstrates a common origin of the head and tail, but more recent evolution of the appendages.

	~~{{STRUCTURE_4eo2\| PDB=4eo2 \| SCENE= }}~~		Structural investigations of a Podoviridae streptococcus phage C1, implications for the mechanism of viral entry.,Aksyuk AA, Bowman VD, Kaufmann B, Fields C, Klose T, Holdaway HA, Fischetti VA, Rossmann MG Proc Natl Acad Sci U S A. 2012 Aug 13. PMID:22891295<ref>PMID:22891295</ref>

	~~===Structure~~ of the ~~bacteriophage C1 tail knob protein, gp12===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22891295}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[4eo2]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_phage_c1 Streptococcus phage c1]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:022891295<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Streptococcus phage c1]]		[[Category: Streptococcus phage c1]]
	[[Category: Aksyuk, A A.]]		[[Category: Aksyuk, A A]]
	[[Category: Rossmann, M G.]]		[[Category: Rossmann, M G]]
	[[Category: Structural protein]]		[[Category: Structural protein]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 05:10, 29 August 2012

2012-08-29T05:10:25Z

← Older revision		Revision as of 05:10, 29 August 2012
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	[[Image:4eo2.~~jpg~~\|left\|200px]]		[[Image:4eo2.png\|left\|200px]]

	{{STRUCTURE_4eo2\| PDB=4eo2 \| SCENE= }}		{{STRUCTURE_4eo2\| PDB=4eo2 \| SCENE= }}
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	===Structure of the bacteriophage C1 tail knob protein, gp12===		===Structure of the bacteriophage C1 tail knob protein, gp12===

			{{ABSTRACT_PUBMED_22891295}}

	==About this Structure==		==About this Structure==
	[[4eo2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_c1 Streptococcus phage c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA].		[[4eo2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_c1 Streptococcus phage c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA].

			==Reference==
			<ref group="xtra">PMID:022891295</ref><references group="xtra"/>
	[[Category: Streptococcus phage c1]]		[[Category: Streptococcus phage c1]]
	[[Category: Aksyuk, A A.]]		[[Category: Aksyuk, A A.]]

OCA at 06:05, 22 August 2012

2012-08-22T06:05:49Z

← Older revision		Revision as of 06:05, 22 August 2012
Line 1:		Line 1:
	~~'''Unreleased structure'''~~		[[Image:4eo2.jpg\|left\|200px]]

	~~The entry~~ 4eo2 ~~is ON HOLD~~ ~~until Paper Publication~~		{{STRUCTURE_4eo2\| PDB=4eo2 \| SCENE= }}

	~~Authors: Aksyuk~~, ~~A.A., Rossmann, M.G.~~		===Structure of the bacteriophage C1 tail knob protein, gp12===

	~~Description~~: ~~Structure of the bacteriophage C1 tail knob~~ protein~~, gp12~~
			==About this Structure==
			[[4eo2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_c1 Streptococcus phage c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO2 OCA].
			[[Category: Streptococcus phage c1]]
			[[Category: Aksyuk, A A.]]
			[[Category: Rossmann, M G.]]
			[[Category: Structural protein]]
			[[Category: Viral protein]]

OCA at 08:49, 16 May 2012

2012-05-16T08:49:03Z

← Older revision		Revision as of 08:49, 16 May 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4eo2 is ON HOLD		The entry 4eo2 is ON HOLD until Paper Publication

	Authors: Aksyuk, A.A., Rossmann, M.G.		Authors: Aksyuk, A.A., Rossmann, M.G.

	Description: Structure of the bacteriophage C1 tail knob protein, gp12		Description: Structure of the bacteriophage C1 tail knob protein, gp12

OCA: Protected "4eo2" [edit=sysop:move=sysop]

2012-04-25T08:55:08Z

Protected "4eo2" [edit=sysop:move=sysop]

← Older revision	Revision as of 08:55, 25 April 2012
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4eo2 is ON HOLD Authors: Aksyuk, A.A., Rossmann, M.G. Description: Structure of the bacteriophage C1 tail knob protein, gp12

2012-04-25T08:55:07Z

New page: '''Unreleased structure''' The entry 4eo2 is ON HOLD Authors: Aksyuk, A.A., Rossmann, M.G. Description: Structure of the bacteriophage C1 tail knob protein, gp12

New page

'''Unreleased structure'''

The entry 4eo2 is ON HOLD

Authors: Aksyuk, A.A., Rossmann, M.G.

Description: Structure of the bacteriophage C1 tail knob protein, gp12