4o08 - Revision history

OCA at 12:36, 1 March 2024

2024-03-01T12:36:49Z

← Older revision		Revision as of 12:36, 1 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [https://pdbe.org/4o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [https://www.ebi.ac.uk/pdbsum/4o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o08 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [https://pdbe.org/4o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [https://www.ebi.ac.uk/pdbsum/4o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o08 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/G9BEX6_PRIMG G9BEX6_PRIMG]		[https://www.uniprot.org/uniprot/G9BEX6_PRIMG G9BEX6_PRIMG]
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Optically pure epoxides are essential chiral precursors for the production of (S)-propranolol, (S)-alprenolol, and other beta-adrenergic receptor blocking drugs. Although the enzymatic production of these bulky epoxides has proven difficult, here we report a method to effectively improve the activity of BmEH, an epoxide hydrolase from Bacillus megaterium ECU1001 toward alpha-naphthyl glycidyl ether, the precursor of (S)-propranolol, by eliminating the steric hindrance near the potential product-release site. Using X-ray crystallography, mass spectrum, and molecular dynamics calculations, we have identified an active tunnel for substrate access and product release of this enzyme. The crystal structures revealed that there is an independent product-release site in BmEH that was not included in other reported epoxide hydrolase structures. By alanine scanning, two mutants, F128A and M145A, targeted to expand the potential product-release site displayed 42 and 25 times higher activities toward alpha-naphthyl glycidyl ether than the wild-type enzyme, respectively. These results show great promise for structure-based rational design in improving the catalytic efficiency of industrial enzymes for bulky substrates.

	Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.,Kong XD, Yuan S, Li L, Chen S, Xu JH, Zhou J Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15717-22. doi:, 10.1073/pnas.1404915111. Epub 2014 Oct 20. PMID:25331869<ref>PMID:25331869</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4o08" style="background-color:#fffaf0;"></div>~~

	==See Also==		==See Also==
	*[[Epoxide hydrolase 3D structures\|Epoxide hydrolase 3D structures]]		*[[Epoxide hydrolase 3D structures\|Epoxide hydrolase 3D structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:49, 18 January 2023

2023-01-18T08:49:40Z

← Older revision		Revision as of 08:49, 18 January 2023
Line 3:		Line 3:
	<StructureSection load='4o08' size='340' side='right'caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4o08' size='340' side='right'caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_14581 Atcc 14581~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [https://pdbe.org/4o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [https://www.ebi.ac.uk/pdbsum/4o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o08 ProSAT]</span></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrimidine-5'-nucleotide_nucleosidase Pyrimidine-5'-nucleotide nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.10 3.2.2.10] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [~~http~~://pdbe.org/4o08 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4o08 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4o08 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/G9BEX6_PRIMG G9BEX6_PRIMG]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
	*[[Epoxide hydrolase\|Epoxide hydrolase]]		*[[Epoxide hydrolase 3D structures\|Epoxide hydrolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 14581]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Pyrimidine-5'-nucleotide nucleosidase~~]]		[[Category: Priestia megaterium]]
	[[Category: Kong~~, X D~~]]		[[Category: Kong XD]]
	[[Category: Xu~~, J H~~]]		[[Category: Xu JH]]
	[[Category: Zhou~~, J H]]~~		[[Category: Zhou JH]]
	~~[[Category: A/b hydrolase fold]]~~
	~~[[Category: Epoxide hydrolase]]~~
	~~[[Category: Hydrolase-hydrolase inhibitor complex~~]]

OCA at 08:38, 10 April 2019

2019-04-10T08:38:29Z

← Older revision		Revision as of 08:38, 10 April 2019
Line 1:		Line 1:

	==Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor==		==Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor==
	<StructureSection load='4o08' size='340' side='right' caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4o08' size='340' side='right'caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Atcc 14581]]
			[[Category: Large Structures]]
	[[Category: Pyrimidine-5'-nucleotide nucleosidase]]		[[Category: Pyrimidine-5'-nucleotide nucleosidase]]
	[[Category: Kong, X D]]		[[Category: Kong, X D]]

OCA at 10:17, 11 August 2016

2016-08-11T10:17:37Z

← Older revision		Revision as of 10:17, 11 August 2016
Line 1:		Line 1:

	==Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor==		==Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor==
	<StructureSection load='4o08' size='340' side='right' caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4o08' size='340' side='right' caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrimidine-5'-nucleotide_nucleosidase Pyrimidine-5'-nucleotide nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.10 3.2.2.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrimidine-5'-nucleotide_nucleosidase Pyrimidine-5'-nucleotide nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.10 3.2.2.10] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [http://www.ebi.ac.uk/pdbsum/4o08 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [http://pdbe.org/4o08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [http://www.ebi.ac.uk/pdbsum/4o08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o08 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4o08" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Epoxide hydrolase\|Epoxide hydrolase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:09, 19 November 2014

2014-11-19T09:09:49Z

← Older revision		Revision as of 09:09, 19 November 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [http://www.ebi.ac.uk/pdbsum/4o08 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [http://www.ebi.ac.uk/pdbsum/4o08 PDBsum]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Optically pure epoxides are essential chiral precursors for the production of (S)-propranolol, (S)-alprenolol, and other beta-adrenergic receptor blocking drugs. Although the enzymatic production of these bulky epoxides has proven difficult, here we report a method to effectively improve the activity of BmEH, an epoxide hydrolase from Bacillus megaterium ECU1001 toward alpha-naphthyl glycidyl ether, the precursor of (S)-propranolol, by eliminating the steric hindrance near the potential product-release site. Using X-ray crystallography, mass spectrum, and molecular dynamics calculations, we have identified an active tunnel for substrate access and product release of this enzyme. The crystal structures revealed that there is an independent product-release site in BmEH that was not included in other reported epoxide hydrolase structures. By alanine scanning, two mutants, F128A and M145A, targeted to expand the potential product-release site displayed 42 and 25 times higher activities toward alpha-naphthyl glycidyl ether than the wild-type enzyme, respectively. These results show great promise for structure-based rational design in improving the catalytic efficiency of industrial enzymes for bulky substrates.

			Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.,Kong XD, Yuan S, Li L, Chen S, Xu JH, Zhou J Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15717-22. doi:, 10.1073/pnas.1404915111. Epub 2014 Oct 20. PMID:25331869<ref>PMID:25331869</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Pyrimidine-5'-nucleotide nucleosidase]]		[[Category: Pyrimidine-5'-nucleotide nucleosidase]]
	[[Category: Kong, X D.]]		[[Category: Kong, X D]]
	[[Category: Xu, J H.]]		[[Category: Xu, J H]]
	[[Category: Zhou, J H.]]		[[Category: Zhou, J H]]
	[[Category: A/b hydrolase fold]]		[[Category: A/b hydrolase fold]]
	[[Category: Epoxide hydrolase]]		[[Category: Epoxide hydrolase]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 11:27, 29 October 2014

2014-10-29T11:27:12Z

← Older revision		Revision as of 11:27, 29 October 2014
Line 1:		Line 1:
	'''~~Unreleased structure~~'''		==Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor==
			<StructureSection load='4o08' size='340' side='right' caption='[[4o08]], [[Resolution\|resolution]] 1.95Å' scene=''>
	~~The entry~~ 4o08 is ~~ON HOLD until Paper Publication~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4o08]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O08 FirstGlance]. <br>
	~~Authors~~: ~~Kong~~, X.D., ~~Zhou~~, J.H., Xu, J.H.		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO6:2-PHENOXYACETAMIDE'>PO6</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4nzz\|4nzz]]</td></tr>
	~~Description~~: ~~Crystal structure of bacillus megaterium epoxide~~ hydrolase in complex ~~with an inhibitor~~		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrimidine-5'-nucleotide_nucleosidase Pyrimidine-5'-nucleotide nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.10 3.2.2.10] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o08 RCSB], [http://www.ebi.ac.uk/pdbsum/4o08 PDBsum]</span></td></tr>
			</table>
			__TOC__
			</StructureSection>
			[[Category: Pyrimidine-5'-nucleotide nucleosidase]]
			[[Category: Kong, X D.]]
			[[Category: Xu, J H.]]
			[[Category: Zhou, J H.]]
			[[Category: A/b hydrolase fold]]
			[[Category: Epoxide hydrolase]]
			[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 07:35, 7 May 2014

2014-05-07T07:35:49Z

← Older revision		Revision as of 07:35, 7 May 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4o08 is ON HOLD		The entry 4o08 is ON HOLD until Paper Publication

	Authors: Kong, X.D., Zhou, J.H., Xu, J.H.		Authors: Kong, X.D., Zhou, J.H., Xu, J.H.

	Description: Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor		Description: Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor

OCA at 09:21, 8 January 2014

2014-01-08T09:21:00Z

← Older revision		Revision as of 09:21, 8 January 2014
Line 5:		Line 5:
	Authors: Kong, X.D., Zhou, J.H., Xu, J.H.		Authors: Kong, X.D., Zhou, J.H., Xu, J.H.

	Description: ~~CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM EPOXIDE HYDROLASE IN COMPLEX WITH AN INHIBITOR~~		Description: Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor

OCA: Protected "4o08" [edit=sysop:move=sysop]

2013-12-25T09:28:47Z

Protected "4o08" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:28, 25 December 2013
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4o08 is ON HOLD Authors: Kong, X.D., Zhou, J.H., Xu, J.H. Description: CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM EPOXIDE HYDROLASE IN COMPLEX WITH A...

2013-12-25T09:28:46Z

New page: '''Unreleased structure''' The entry 4o08 is ON HOLD Authors: Kong, X.D., Zhou, J.H., Xu, J.H. Description: CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM EPOXIDE HYDROLASE IN COMPLEX WITH A...

New page

'''Unreleased structure'''

The entry 4o08 is ON HOLD

Authors: Kong, X.D., Zhou, J.H., Xu, J.H.

Description: CRYSTAL STRUCTURE OF BACILLUS MEGATERIUM EPOXIDE HYDROLASE IN COMPLEX WITH AN INHIBITOR