4oby - Revision history

OCA at 17:09, 20 September 2023

2023-09-20T17:09:30Z

← Older revision		Revision as of 17:09, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OBY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OBY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.574Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [https://pdbe.org/4oby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [https://www.ebi.ac.uk/pdbsum/4oby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oby ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [https://pdbe.org/4oby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [https://www.ebi.ac.uk/pdbsum/4oby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oby ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:16, 25 January 2023

2023-01-25T07:16:09Z

← Older revision		Revision as of 07:16, 25 January 2023
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	<StructureSection load='4oby' size='340' side='right'caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>		<StructureSection load='4oby' size='340' side='right'caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OBY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OBY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene~~></td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">argS, b1876, JW1865 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [https://pdbe.org/4oby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [https://www.ebi.ac.uk/pdbsum/4oby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oby ProSAT]</span></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine--tRNA_ligase Arginine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.19 6.1.1.19] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [~~http~~://pdbe.org/4oby PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4oby PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4oby ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/SYR_ECOLI SYR_ECOLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Arginine~~-~~-tRNA ligase]]~~		[[Category: Escherichia coli K-12]]
	~~[[Category: Ecoli~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bi, K]]		[[Category: Bi K]]
	[[Category: Dong, J]]		[[Category: Dong J]]
	[[Category: Gao, F]]		[[Category: Gao F]]
	[[Category: Gong, W]]		[[Category: Gong W]]
	[[Category: Wang, J]]		[[Category: Wang J]]
	[[Category: Wang, Y]]		[[Category: Wang Y]]
	[[Category: Zheng, Y]]		[[Category: Zheng Y]]
	~~[[Category: Ligase~~]]

OCA at 12:12, 17 July 2019

2019-07-17T12:12:29Z

← Older revision		Revision as of 12:12, 17 July 2019
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	==Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition==		==Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition==
	<StructureSection load='4oby' size='340' side='right' caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>		<StructureSection load='4oby' size='340' side='right'caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OBY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OBY FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 4oby" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4oby" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Aminoacyl tRNA synthetase 3D structures\|Aminoacyl tRNA synthetase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Arginine--tRNA ligase]]		[[Category: Arginine--tRNA ligase]]
	[[Category: Ecoli]]		[[Category: Ecoli]]
			[[Category: Large Structures]]
	[[Category: Bi, K]]		[[Category: Bi, K]]
	[[Category: Dong, J]]		[[Category: Dong, J]]

OCA at 11:10, 4 August 2016

2016-08-04T11:10:51Z

← Older revision		Revision as of 11:10, 4 August 2016
Line 1:		Line 1:

	==Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition==		==Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition==
	<StructureSection load='4oby' size='340' side='right' caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>		<StructureSection load='4oby' size='340' side='right' caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">argS, b1876, JW1865 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">argS, b1876, JW1865 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine--tRNA_ligase Arginine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.19 6.1.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine--tRNA_ligase Arginine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.19 6.1.1.19] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [http://www.ebi.ac.uk/pdbsum/4oby PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [http://pdbe.org/4oby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [http://www.ebi.ac.uk/pdbsum/4oby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oby ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4oby" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:39, 22 December 2014

2014-12-22T04:39:54Z

← Older revision		Revision as of 04:39, 22 December 2014
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	~~{{STRUCTURE_4oby\| PDB=4oby \| SCENE= }}~~		==Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition==
	===Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition===		<StructureSection load='4oby' size='340' side='right' caption='[[4oby]], [[Resolution\|resolution]] 2.57Å' scene=''>
	~~{{ABSTRACT_PUBMED_24474195}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4oby]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OBY FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">argS, b1876, JW1865 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine--tRNA_ligase Arginine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.19 6.1.1.19] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oby OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oby RCSB], [http://www.ebi.ac.uk/pdbsum/4oby PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The arginyl-tRNA synthetase (ArgRS) catalyzes the esterification reaction between L-arginine and its cognate tRNAArg. Previously reported structures of ArgRS shed considerable light on the tRNA recognition mechanism, while the aspect of amino acid binding in ArgRS remains largely unexplored. Here we report the first crystal structure of E. coli ArgRS (eArgRS) complexed with L-arginine, and a series of mutational studies using isothermal titration calorimetry (ITC). Combined with previously reported work on ArgRS, our results elucidated the structural and functional roles of a series of important residues in the active site, which furthered our understanding of this unique enzyme.

	~~==About this Structure==~~		Crystal structure of E. coli arginyl-tRNA synthetase and ligand binding studies revealed key residues in arginine recognition.,Bi K, Zheng Y, Gao F, Dong J, Wang J, Wang Y, Gong W Protein Cell. 2014 Jan 30. PMID:24474195<ref>PMID:24474195</ref>
	~~[[4oby]] is a 1 chain~~ structure. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.ac.~~il/oca-bin~~/~~ocashort?id=4OBY OCA].~~

	==~~Reference~~==		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~<ref group="xtra">PMID:024474195</ref>~~<references ~~group="xtra"~~/><~~references~~/>		</div>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Arginine--tRNA ligase]]		[[Category: Arginine--tRNA ligase]]
	[[Category: Bi, K.]]		[[Category: Ecoli]]
	[[Category: Dong, J.]]		[[Category: Bi, K]]
	[[Category: Gao, F.]]		[[Category: Dong, J]]
	[[Category: Gong, W.]]		[[Category: Gao, F]]
	[[Category: Wang, J.]]		[[Category: Gong, W]]
	[[Category: Wang, Y.]]		[[Category: Wang, J]]
	[[Category: Zheng, Y.]]		[[Category: Wang, Y]]
			[[Category: Zheng, Y]]
	[[Category: Ligase]]		[[Category: Ligase]]

OCA at 04:59, 13 February 2014

2014-02-13T04:59:10Z

← Older revision		Revision as of 04:59, 13 February 2014
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	~~'''Unreleased structure'''~~		{{STRUCTURE_4oby\| PDB=4oby \| SCENE= }}
			===Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition===
			{{ABSTRACT_PUBMED_24474195}}

	~~The entry~~ 4oby is ~~ON HOLD until Paper Publication~~		==About this Structure==
			[[4oby]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBY OCA].

	~~Authors~~: Bi, K.~~, Zheng, Y.,~~ Dong, J., Gao, F., Wang, J., Wang, Y., ~~Gong, W~~.		==Reference==
			<ref group="xtra">PMID:024474195</ref><references group="xtra"/><references/>
	~~Description~~: ~~Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition~~		[[Category: Arginine--tRNA ligase]]
			[[Category: Bi, K.]]
			[[Category: Dong, J.]]
			[[Category: Gao, F.]]
			[[Category: Gong, W.]]
			[[Category: Wang, J.]]
			[[Category: Wang, Y.]]
			[[Category: Zheng, Y.]]
			[[Category: Ligase]]

OCA at 07:06, 29 January 2014

2014-01-29T07:06:20Z

← Older revision		Revision as of 07:06, 29 January 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4oby is ON HOLD		The entry 4oby is ON HOLD until Paper Publication

	Authors: ~~Kelei~~, B., ~~Yueting~~, Z., ~~Jianshu~~, D., ~~Feng~~, G., ~~Jiangyun~~, W., Yi, W., ~~Weimin~~, G.		Authors: Bi, K., Zheng, Y., Dong, J., Gao, F., Wang, J., Wang, Y., Gong, W.

	Description: Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition		Description: Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition

OCA: Protected "4oby" [edit=sysop:move=sysop]

2014-01-15T07:45:48Z

Protected "4oby" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:45, 15 January 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4oby is ON HOLD Authors: Kelei, B., Yueting, Z., Jianshu, D., Feng, G., Jiangyun, W., Yi, W., Weimin, G. Description: Crystal Structure of E.coli A...

2014-01-15T07:45:47Z

New page: '''Unreleased structure''' The entry 4oby is ON HOLD Authors: Kelei, B., Yueting, Z., Jianshu, D., Feng, G., Jiangyun, W., Yi, W., Weimin, G. Description: Crystal Structure of E.coli A...

New page

'''Unreleased structure'''

The entry 4oby is ON HOLD

Authors: Kelei, B., Yueting, Z., Jianshu, D., Feng, G., Jiangyun, W., Yi, W., Weimin, G.

Description: Crystal Structure of E.coli Arginyl-tRNA Synthetase and Ligand Binding Studies Revealed Key Residues in Arginine Recognition