4omp - Revision history

OCA at 17:16, 20 September 2023

2023-09-20T17:16:43Z

← Older revision		Revision as of 17:16, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OMP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OMP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [https://pdbe.org/4omp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [https://www.ebi.ac.uk/pdbsum/4omp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [https://pdbe.org/4omp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [https://www.ebi.ac.uk/pdbsum/4omp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:33, 25 January 2023

2023-01-25T07:33:41Z

← Older revision		Revision as of 07:33, 25 January 2023
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	<StructureSection load='4omp' size='340' side='right'caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4omp' size='340' side='right'caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OMP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OMP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene~~></td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [https://pdbe.org/4omp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [https://www.ebi.ac.uk/pdbsum/4omp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>~~
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [~~http~~://pdbe.org/4omp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4omp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/SRC_CHICK SRC_CHICK]] Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each SRC kinase is very difficult. SRC appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. Receptor clustering or dimerization leads to recruitment of SRC to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains. Plays an important role in the regulation of cytoskeletal organization through phosphorylation of specific substrates involved in this process. When cells adhere via focal adhesions to the extra-cellular matrix, signals are transmitted by integrins into the cell and result in tyrosine phosphorylation of a number of focal adhesion proteins, including PTK2/FAK1 and paxillin (PXN). Also active at the sites of cell-cell contact adherens junctions and at gap junctions. Implicated in the regulation of pre-mRNA-processing. Might be involved not only in mediating the transduction of mitogenic signals at the level of the plasma membrane but also in controlling progression through the cell cycle via interaction with regulatory proteins in the nucleus.<ref>PMID:1717492</ref> <ref>PMID:8550628</ref>		[https://www.uniprot.org/uniprot/SRC_CHICK SRC_CHICK] Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each SRC kinase is very difficult. SRC appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. Receptor clustering or dimerization leads to recruitment of SRC to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains. Plays an important role in the regulation of cytoskeletal organization through phosphorylation of specific substrates involved in this process. When cells adhere via focal adhesions to the extra-cellular matrix, signals are transmitted by integrins into the cell and result in tyrosine phosphorylation of a number of focal adhesion proteins, including PTK2/FAK1 and paxillin (PXN). Also active at the sites of cell-cell contact adherens junctions and at gap junctions. Implicated in the regulation of pre-mRNA-processing. Might be involved not only in mediating the transduction of mitogenic signals at the level of the plasma membrane but also in controlling progression through the cell cycle via interaction with regulatory proteins in the nucleus.<ref>PMID:1717492</ref> <ref>PMID:8550628</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
	*[[Tyrosine kinase\|Tyrosine kinase]]		*[[Tyrosine kinase 3D structures\|Tyrosine kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Chick~~]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Non-specific protein-tyrosine kinase]]~~		[[Category: Bacarizo J]]
	[[Category: Bacarizo, J]]		[[Category: Camara-Artigas A]]
	[[Category: Camara-Artigas, A]]
	~~[[Category: Beta-barrel sandwich]]~~
	~~[[Category: Kinase]]~~
	~~[[Category: Proline rich motif]]~~
	~~[[Category: Transferase~~]]

OCA at 07:20, 17 April 2019

2019-04-17T07:20:37Z

← Older revision		Revision as of 07:20, 17 April 2019
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	==Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K==		==Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K==
	<StructureSection load='4omp' size='340' side='right' caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4omp' size='340' side='right'caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OMP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OMP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://pdbe.org/4omp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://pdbe.org/4omp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Chick]]
			[[Category: Large Structures]]
	[[Category: Non-specific protein-tyrosine kinase]]		[[Category: Non-specific protein-tyrosine kinase]]
	[[Category: Bacarizo, J]]		[[Category: Bacarizo, J]]

OCA at 09:47, 4 August 2016

2016-08-04T09:47:16Z

← Older revision		Revision as of 09:47, 4 August 2016
Line 1:		Line 1:

	==Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K==		==Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K==
	<StructureSection load='4omp' size='340' side='right' caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4omp' size='340' side='right' caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://pdbe.org/4omp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4omp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4omp" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Tyrosine kinase\|Tyrosine kinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:01, 25 December 2014

2014-12-25T08:01:11Z

← Older revision		Revision as of 08:01, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/SRC_CHICK SRC_CHICK]] Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each SRC kinase is very difficult. SRC appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. Receptor clustering or dimerization leads to recruitment of SRC to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains. Plays an important role in the regulation of cytoskeletal organization through phosphorylation of specific substrates involved in this process. When cells adhere via focal adhesions to the extra-cellular matrix, signals are transmitted by integrins into the cell and result in tyrosine phosphorylation of a number of focal adhesion proteins, including PTK2/FAK1 and paxillin (PXN). Also active at the sites of cell-cell contact adherens junctions and at gap junctions. Implicated in the regulation of pre-mRNA-processing. Might be involved not only in mediating the transduction of mitogenic signals at the level of the plasma membrane but also in controlling progression through the cell cycle via interaction with regulatory proteins in the nucleus.<ref>PMID:1717492</ref> <ref>PMID:8550628</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:46, 17 December 2014

2014-12-17T08:46:16Z

@@ Line 8: / Line 8: @@
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum]</span></td></tr>
 </table>
 __TOC__
 </StructureSection>

OCA at 16:22, 10 December 2014

2014-12-10T16:22:29Z

← Older revision		Revision as of 16:22, 10 December 2014
Line 1:		Line 1:
	'''~~Unreleased structure~~'''		==Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K==
			<StructureSection load='4omp' size='340' side='right' caption='[[4omp]], [[Resolution\|resolution]] 2.00Å' scene=''>
	~~The entry~~ 4omp is ~~ON HOLD until Paper Publication~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4omp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OMP FirstGlance]. <br>
	~~Authors~~: ~~Camara~~-~~Artigas~~, A., ~~Bacarizo~~, J.		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jz3\|4jz3]], [[4jz4\|4jz4]], [[4hvu\|4hvu]], [[4hvv\|4hvv]], [[4hvw\|4hvw]], [[3fj5\|3fj5]], [[4omq\|4omq]], [[4omo\|4omo]], [[4omn\|4omn]], [[4omm\|4omm]], [[4oml\|4oml]]</td></tr>
	~~Description~~: ~~Crystal structure of the intertwined dimer of the c~~-~~Src~~ tyrosine kinase ~~SH3 domain mutant Q128K~~		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4omp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4omp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4omp RCSB], [http://www.ebi.ac.uk/pdbsum/4omp PDBsum]</span></td></tr>
			</table>
			__TOC__
			</StructureSection>
			[[Category: Non-specific protein-tyrosine kinase]]
			[[Category: Bacarizo, J]]
			[[Category: Camara-Artigas, A]]
			[[Category: Beta-barrel sandwich]]
			[[Category: Kinase]]
			[[Category: Proline rich motif]]
			[[Category: Transferase]]

OCA at 06:12, 8 October 2014

2014-10-08T06:12:57Z

← Older revision		Revision as of 06:12, 8 October 2014
Line 3:		Line 3:
	The entry 4omp is ON HOLD until Paper Publication		The entry 4omp is ON HOLD until Paper Publication

	Authors: Camara-Artigas, A, Bacarizo, J		Authors: Camara-Artigas, A., Bacarizo, J.

	Description: Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K		Description: Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K

OCA at 16:16, 19 February 2014

2014-02-19T16:16:52Z

← Older revision		Revision as of 16:16, 19 February 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4omp is ON HOLD		The entry 4omp is ON HOLD until Paper Publication

	Authors: Camara-Artigas, A, Bacarizo, J		Authors: Camara-Artigas, A, Bacarizo, J

	Description: Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K		Description: Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K

OCA: Protected "4omp" [edit=sysop:move=sysop]

2014-02-05T10:33:28Z

Protected "4omp" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:33, 5 February 2014
(No difference)