4pp2 - Revision history

OCA: Redirecting to 5vco

2022-04-27T11:35:24Z

Redirecting to 5vco

← Older revision		Revision as of 11:35, 27 April 2022
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			#REDIRECT [[5vco]] This PDB entry is obsolete and replaced by 5vco
	~~==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==~~
	~~<StructureSection load='4pp2' size='340' side='right'caption='~~[[~~4pp2~~]]~~, [[Resolution\|resolution]] 2.74Å' scene=''>~~
	~~== Structural highlights ==~~
	<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [https://pdbe.org/4pp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [https://www.ebi.ac.uk/pdbsum/4pp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp2 ProSAT]</span></td></tr>
	~~</table>~~
	~~== Function ==~~
	~~[[https://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.~~
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	~~Der p 1~~ is a major allergen from the house dust mite, Dermatophagoides pteronyssinus, that belongs to the papain-like cysteine protease family. To investigate the antigenic determinants of Der p 1, we determined two crystal structures of Der p 1 in complex with the Fab fragments of mAbs 5H8 or 10B9. Epitopes for these two Der p 1-specific Abs are located in different, nonoverlapping parts of the Der p 1 molecule. Nevertheless, surface area and identity of the amino acid residues involved in hydrogen bonds between allergen and Ab are similar. The epitope for mAb 10B9 only showed a partial overlap with the previously reported epitope for mAb 4C1, a cross-reactive mAb that binds Der p 1 and its homolog Der f 1 from Dermatophagoides farinae. Upon binding to Der p 1, the Fab fragment of mAb 10B9 was found to form a very rare alpha helix in its third CDR of the H chain. To provide an overview of the surface properties of the interfaces formed by the complexes of Der p 1-10B9 and Der p 1-5H8, along with the complexes of 4C1 with Der p 1 and Der f 1, a broad analysis of the surfaces and hydrogen bonds of all complexes of Fab-protein or Fab-peptide was performed. This work provides detailed insight into the cross-reactive and specific allergen-Ab interactions in group 1 mite allergens. The surface data of Fab-protein and Fab-peptide interfaces can be used in the design of conformational epitopes with reduced Ab binding for immunotherapy.

	Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.,Osinski T, Pomes A, Majorek KA, Glesner J, Offermann LR, Vailes LD, Chapman MD, Minor W, Chruszcz M J Immunol. 2015 Jul 1;195(1):307-16. doi: 10.4049/jimmunol.1402199. Epub 2015 May, 29. PMID:26026055<ref>PMID:26026055</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4pp2" style="background-color:#fffaf0;"></div>~~

	~~==See Also==~~
	*[[Antibody 3D structures\|Antibody 3D structures]]
	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	~~== References ==~~
	~~<references/>~~
	~~__TOC__~~
	~~</StructureSection>~~
	~~[[Category: Dermatophagoides pteronyssinus]]~~
	~~[[Category: Large Structures]]~~
	~~[[Category: Lk3 transgenic mice]]~~
	~~[[Category: Chapman, M D]]~~
	~~[[Category: Chruszcz, M]]~~
	~~[[Category: Glesner, J]]~~
	~~[[Category: Majorek, K A]]~~
	~~[[Category: Minor, W]]~~
	~~[[Category: Offermann, L R]]~~
	~~[[Category: Osinski, S]]~~
	~~[[Category: Osinski, T]]~~
	~~[[Category: Pomes, A]]~~
	~~[[Category: Vailes, L D]]~~
	~~[[Category: Allergen]]~~
	~~[[Category: Antibody]]~~
	~~[[Category: Immune system]]~~

OCA at 10:05, 13 April 2022

2022-04-13T10:05:41Z

← Older revision		Revision as of 10:05, 13 April 2022
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	<StructureSection load='4pp2' size='340' side='right'caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>		<StructureSection load='4pp2' size='340' side='right'caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [~~http~~://pdbe.org/4pp2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4pp2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [https://pdbe.org/4pp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [https://www.ebi.ac.uk/pdbsum/4pp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.		[[https://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	==See Also==		==See Also==
	*[[Antibody 3D structures\|Antibody 3D structures]]		*[[Antibody 3D structures\|Antibody 3D structures]]
			*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:07, 19 February 2020

2020-02-19T08:07:42Z

← Older revision		Revision as of 08:07, 19 February 2020
Line 1:		Line 1:

	==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==		==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==
	<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>		<StructureSection load='4pp2' size='340' side='right'caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>
Line 22:		Line 22:

	==See Also==		==See Also==
	*[[3D structures ~~of antibody~~\|3D structures ~~of antibody~~]]		*[[Antibody 3D structures\|Antibody 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Dermatophagoides pteronyssinus]]		[[Category: Dermatophagoides pteronyssinus]]
			[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Chapman, M D]]		[[Category: Chapman, M D]]

OCA at 08:43, 22 November 2017

2017-11-22T08:43:24Z

← Older revision		Revision as of 08:43, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>		<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/~~Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: Dermatophagoides pteronyssinus]]		[[Category: Dermatophagoides pteronyssinus]]
			[[Category: Lk3 transgenic mice]]
	[[Category: Chapman, M D]]		[[Category: Chapman, M D]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]

OCA at 09:01, 9 August 2017

2017-08-09T09:01:21Z

@@ Line 11: / Line 11: @@
 == Function ==
 [[http://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
 __TOC__
 </StructureSection>

OCA at 17:14, 18 January 2017

2017-01-18T17:14:18Z

← Older revision		Revision as of 17:14, 18 January 2017
Line 1:		Line 1:

	==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==		==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==
	<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>		<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4pp2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [http://pdbe.org/4pp2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4pp2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pp2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 11:12, 8 April 2015

2015-04-08T11:12:52Z

← Older revision		Revision as of 11:12, 8 April 2015
Line 1:		Line 1:
	'''~~Unreleased structure~~'''		==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9==
			<StructureSection load='4pp2' size='340' side='right' caption='[[4pp2]], [[Resolution\|resolution]] 2.74Å' scene=''>
	~~The entry~~ 4pp2 is ~~ON HOLD until Paper Publication~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4pp2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP2 FirstGlance]. <br>
	~~Authors~~: ~~Osinski~~, T., ~~Majorek~~, K.A., ~~Pomes~~, A., ~~Offermann, L~~.R.~~, Osinski, S~~., ~~Glesner, J~~.~~, Vailes, L~~.D.~~, Chapman, M~~.D., ~~Minor~~, W., Chruszcz, M.		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3rvw\|3rvw]], [[3rvv\|3rvv]], [[3rvx\|3rvx]], [[4poz\|4poz]], [[4pp1\|4pp1]]</td></tr>
	~~Description~~: ~~The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9~~		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4pp2 PDBsum]</span></td></tr>
	[[Category: ~~Pomes~~, A]]		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
			__TOC__
			</StructureSection>
			[[Category: Dermatophagoides pteronyssinus]]
			[[Category: Chapman, M D]]
			[[Category: Chruszcz, M]]
			[[Category: Glesner, J]]
			[[Category: Majorek, K A]]
			[[Category: Minor, W]]
			[[Category: Offermann, L R]]
	[[Category: Osinski, S]]		[[Category: Osinski, S]]
	~~[[Category: Glesner, J]]~~
	~~[[Category: Majorek, K.A]]~~
	~~[[Category: Vailes, L.D]]~~
	~~[[Category: Chruszcz, M]]~~
	[[Category: Osinski, T]]		[[Category: Osinski, T]]
	[[Category: ~~Offermann~~, L.R]]		[[Category: Pomes, A]]
	[[Category: ~~Minor, W~~]]		[[Category: Vailes, L D]]
	[[Category: ~~Chapman, M.D~~]]		[[Category: Allergen]]
			[[Category: Antibody]]
			[[Category: Immune system]]

OCA at 15:09, 24 December 2014

2014-12-24T15:09:32Z

← Older revision		Revision as of 15:09, 24 December 2014
Line 6:		Line 6:

	Description: The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9		Description: The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9
			[[Category: Unreleased Structures]]
			[[Category: Pomes, A]]
			[[Category: Osinski, S]]
			[[Category: Glesner, J]]
			[[Category: Majorek, K.A]]
			[[Category: Vailes, L.D]]
			[[Category: Chruszcz, M]]
			[[Category: Osinski, T]]
			[[Category: Offermann, L.R]]
			[[Category: Minor, W]]
			[[Category: Chapman, M.D]]

OCA: Protected "4pp2" [edit=sysop:move=sysop]

2014-03-12T12:33:11Z

Protected "4pp2" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:33, 12 March 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4pp2 is ON HOLD until Paper Publication Authors: Osinski, T., Majorek, K.A., Pomes, A., Offermann, L.R., Osinski, S., Glesner, J., Vailes, L.D., Cha...

2014-03-12T12:33:10Z

New page: '''Unreleased structure''' The entry 4pp2 is ON HOLD until Paper Publication Authors: Osinski, T., Majorek, K.A., Pomes, A., Offermann, L.R., Osinski, S., Glesner, J., Vailes, L.D., Cha...

New page

'''Unreleased structure'''

The entry 4pp2 is ON HOLD until Paper Publication

Authors: Osinski, T., Majorek, K.A., Pomes, A., Offermann, L.R., Osinski, S., Glesner, J., Vailes, L.D., Chapman, M.D., Minor, W., Chruszcz, M.

Description: The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 10B9