4ref - Revision history

OCA at 08:59, 20 March 2024

2024-03-20T08:59:53Z

← Older revision		Revision as of 08:59, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4REF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4REF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [https://pdbe.org/4ref PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [https://www.ebi.ac.uk/pdbsum/4ref PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ref ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [https://pdbe.org/4ref PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [https://www.ebi.ac.uk/pdbsum/4ref PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ref ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>		[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Apoptotic resistance is becoming a significant obstacle for cancer therapy as the majority of treatment takes the route of apoptotic induction. It is of great importance to develop an alternative strategy to induce cancer cell death. We previously reported that autophagic cell death mediated by nuclear receptor TR3 and driven by a chemical agonist, 1-(3,4,5-trihydroxyphenyl)nonan-1-one (THPN), is highly effective in the therapy of melanoma but not any other cancer types. Here, we discovered that the insensitivity of cancer cells to THPN originated from a high cellular Akt2 activity. Akt2 phosphorylation interferes with TR3 export to cytoplasm and targeting to mitochondria, which lead to the autophagic induction. Therefore, the TR3-mediated autophagy could be effectively induced in the otherwise insensitive cells by downregulating Akt2 activity. Highly effective antineoplastic compounds are developed through optimizing the structure of THPN. This study implicates a general strategy for cancer therapy by the induction of autophagic cell death.

	Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity.,Wang WJ, Wang Y, Hou PP, Li FW, Zhou B, Chen HZ, Bian XL, Cai QX, Xing YZ, He JP, Zhang H, Huang PQ, Lin T, Wu Q Chem Biol. 2015 Aug 20;22(8):1040-51. doi: 10.1016/j.chembiol.2015.06.023. Epub, 2015 Jul 30. PMID:26235054<ref>PMID:26235054</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 4ref" style="background-color:#fffaf0;"></div>~~
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:52, 2 March 2023

2023-03-02T06:52:26Z

← Older revision		Revision as of 06:52, 2 March 2023
Line 1:		Line 1:

	==Crystal Structure of TR3 LBD_L449W in complex with Molecule 2==		==Crystal Structure of TR3 LBD_L449W in complex with Molecule 2==
	<StructureSection load='4ref' size='340' side='right' caption='[[4ref]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4ref' size='340' side='right'caption='[[4ref]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4REF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4REF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ree\|4ree]], [[4re8\|4re8]], [[4whf\|4whf]], [[4whg\|4whg]]</td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [https://pdbe.org/4ref PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [https://www.ebi.ac.uk/pdbsum/4ref PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ref ProSAT]</span></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [~~http~~://pdbe.org/4ref PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ref PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ref ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>		[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Cai~~, Q X~~]]		[[Category: Large Structures]]
	[[Category: Hou~~, P P~~]]		[[Category: Cai QX]]
	[[Category: Li~~, A Z~~]]		[[Category: Hou PP]]
	[[Category: Li~~, F W~~]]		[[Category: Li AZ]]
	[[Category: Lin~~, T W~~]]		[[Category: Li FW]]
	[[Category: Tian~~, X Y~~]]		[[Category: Lin TW]]
	[[Category: Wang~~, W J~~]]		[[Category: Tian XY]]
	[[Category: Wu, Q]]		[[Category: Wang WJ]]
	[[Category: Yuan, W]]		[[Category: Wu Q]]
	~~[[Category: Lbd]]~~		[[Category: Yuan W]]
	~~[[Category: Transcription~~]]

OCA at 09:04, 22 November 2017

2017-11-22T09:04:35Z

← Older revision		Revision as of 09:04, 22 November 2017
Line 1:		Line 1:

	==Crystal Structure of TR3 LBD_L449W in complex with Molecule 2==		==Crystal Structure of TR3 LBD_L449W in complex with Molecule 2==
	<StructureSection load='4ref' size='340' side='right' caption='[[4ref]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4ref' size='340' side='right' caption='[[4ref]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4REF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4REF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ree\|4ree]], [[4re8\|4re8]], [[4whf\|4whf]], [[4whg\|4whg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ree\|4ree]], [[4re8\|4re8]], [[4whf\|4whf]], [[4whg\|4whg]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [http://www.ebi.ac.uk/pdbsum/4ref PDBsum]</span></td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [http://pdbe.org/4ref PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [http://www.ebi.ac.uk/pdbsum/4ref PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ref ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4ref" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
	[[Category: Cai, Q X]]		[[Category: Cai, Q X]]
	[[Category: Hou, P P]]		[[Category: Hou, P P]]

OCA at 11:12, 9 September 2015

2015-09-09T11:12:03Z

← Older revision		Revision as of 11:12, 9 September 2015
Line 1:		Line 1:
	'''~~Unreleased~~ structure'''		==Crystal Structure of TR3 LBD_L449W in complex with Molecule 2==
			<StructureSection load='4ref' size='340' side='right' caption='[[4ref]], [[Resolution\|resolution]] 2.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4ref]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4REF FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3N0:1-(3,4,5-TRIHYDROXYPHENYL)HEXAN-1-ONE'>3N0</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ree\|4ree]], [[4re8\|4re8]], [[4whf\|4whf]], [[4whg\|4whg]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ref FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ref OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ref RCSB], [http://www.ebi.ac.uk/pdbsum/4ref PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Apoptotic resistance is becoming a significant obstacle for cancer therapy as the majority of treatment takes the route of apoptotic induction. It is of great importance to develop an alternative strategy to induce cancer cell death. We previously reported that autophagic cell death mediated by nuclear receptor TR3 and driven by a chemical agonist, 1-(3,4,5-trihydroxyphenyl)nonan-1-one (THPN), is highly effective in the therapy of melanoma but not any other cancer types. Here, we discovered that the insensitivity of cancer cells to THPN originated from a high cellular Akt2 activity. Akt2 phosphorylation interferes with TR3 export to cytoplasm and targeting to mitochondria, which lead to the autophagic induction. Therefore, the TR3-mediated autophagy could be effectively induced in the otherwise insensitive cells by downregulating Akt2 activity. Highly effective antineoplastic compounds are developed through optimizing the structure of THPN. This study implicates a general strategy for cancer therapy by the induction of autophagic cell death.

	~~The entry 4ref is ON HOLD until Paper Publication~~		Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity.,Wang WJ, Wang Y, Hou PP, Li FW, Zhou B, Chen HZ, Bian XL, Cai QX, Xing YZ, He JP, Zhang H, Huang PQ, Lin T, Wu Q Chem Biol. 2015 Aug 20;22(8):1040-51. doi: 10.1016/j.chembiol.2015.06.023. Epub, 2015 Jul 30. PMID:26235054<ref>PMID:26235054</ref>

	~~Authors: Li~~, F.W., Cai, Q.X~~., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W.,~~ Hou, P.P~~., Wu, Q., Lin, T.W.~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~Description~~: ~~Crystal Structure of TR3 LBD_L449W in complex with Molecule 2~~		== References ==
	[[Category: ~~Unreleased Structures~~]]		<references/>
	[[Category: Li, ~~A.Z~~]]		__TOC__
	[[Category: ~~Cai~~, Q.X]]		</StructureSection>
	[[Category: ~~Hou~~, ~~P.P~~]]		[[Category: Cai, Q X]]
	[[Category: ~~Tian~~, ~~X.Y~~]]		[[Category: Hou, P P]]
			[[Category: Li, A Z]]
			[[Category: Li, F W]]
			[[Category: Lin, T W]]
			[[Category: Tian, X Y]]
			[[Category: Wang, W J]]
			[[Category: Wu, Q]]
	[[Category: Yuan, W]]		[[Category: Yuan, W]]
	[[Category: ~~Lin, T.W~~]]		[[Category: Lbd]]
	[[Category: ~~Wu, Q]]~~		[[Category: Transcription]]
	~~[[Category: Wang, W.J]]~~
	~~[[Category: Li, F.W~~]]

OCA at 16:47, 24 December 2014

2014-12-24T16:47:06Z

← Older revision		Revision as of 16:47, 24 December 2014
Line 6:		Line 6:

	Description: Crystal Structure of TR3 LBD_L449W in complex with Molecule 2		Description: Crystal Structure of TR3 LBD_L449W in complex with Molecule 2
			[[Category: Unreleased Structures]]
			[[Category: Li, A.Z]]
			[[Category: Cai, Q.X]]
			[[Category: Hou, P.P]]
			[[Category: Tian, X.Y]]
			[[Category: Yuan, W]]
			[[Category: Lin, T.W]]
			[[Category: Wu, Q]]
			[[Category: Wang, W.J]]
			[[Category: Li, F.W]]

OCA at 08:15, 3 December 2014

2014-12-03T08:15:47Z

← Older revision		Revision as of 08:15, 3 December 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4ref is ON HOLD		The entry 4ref is ON HOLD until Paper Publication

	Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W., Hou, P.P., Wu, Q., Lin, T.W.		Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W., Hou, P.P., Wu, Q., Lin, T.W.

	Description: Crystal Structure of TR3 LBD_L449W in complex with Molecule 2		Description: Crystal Structure of TR3 LBD_L449W in complex with Molecule 2

OCA: Protected "4ref" [edit=sysop:move=sysop]

2014-10-01T23:11:12Z

Protected "4ref" [edit=sysop:move=sysop]

← Older revision	Revision as of 23:11, 1 October 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4ref is ON HOLD Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W., Hou, P.P., Wu, Q., Lin, T.W. Description: Crystal Structu...

2014-10-01T23:11:11Z

New page: '''Unreleased structure''' The entry 4ref is ON HOLD Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W., Hou, P.P., Wu, Q., Lin, T.W. Description: Crystal Structu...

New page

'''Unreleased structure'''

The entry 4ref is ON HOLD

Authors: Li, F.W., Cai, Q.X., Li, A.Z., Tian, X.Y., Wang, W.J., Yuan, W., Hou, P.P., Wu, Q., Lin, T.W.

Description: Crystal Structure of TR3 LBD_L449W in complex with Molecule 2