4rob - Revision history

OCA at 17:53, 20 September 2023

2023-09-20T17:53:00Z

← Older revision		Revision as of 17:53, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ROB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [https://pdbe.org/4rob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [https://www.ebi.ac.uk/pdbsum/4rob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [https://pdbe.org/4rob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [https://www.ebi.ac.uk/pdbsum/4rob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:22, 8 March 2023

2023-03-08T08:22:03Z

← Older revision		Revision as of 08:22, 8 March 2023
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	==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==		==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==
	<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4rob' size='340' side='right'caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Anoga Anoga~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ROB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [https://pdbe.org/4rob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [https://www.ebi.ac.uk/pdbsum/4rob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRPN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7165 ANOGA])</td></tr>~~
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [~~http~~://pdbe.org/4rob PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rob PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/SP2_ANOGA SP2_ANOGA] Serine protease inhibitor that functions in the melanization-mediated immune response (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing the activation of phenoloxidases through the inhibiting of serine proteases CLIPB9 and CLIPB10, negatively regulates melanization in the hemolymph (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing melanization, has a detrimental role during P.berghei parasite mediated-infection and invasion of the mosquito midgut (PubMed:16113656).<ref>PMID:16113656</ref> <ref>PMID:20953892</ref> <ref>PMID:21465556</ref> <ref>PMID:25525260</ref> <ref>PMID:33045027</ref> <ref>PMID:33520733</ref>

			==See Also==
			*[[Serpin 3D structures\|Serpin 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Anoga~~]]		[[Category: Anopheles gambiae]]
	[[Category: An, C]]		[[Category: Large Structures]]
	[[Category: Battaile~~, K P~~]]		[[Category: An C]]
	[[Category: Lovell, S]]		[[Category: Battaile KP]]
	[[Category: Meekins~~, D A~~]]		[[Category: Lovell S]]
	[[Category: Michel, K]]		[[Category: Meekins DA]]
	[[Category: Zhang, X]]		[[Category: Michel K]]
	~~[[Category: Hydrolase inhibitor]]~~		[[Category: Zhang X]]
	~~[[Category: Insect immunity]]~~
	~~[[Category: Serine protease inhibitor]]~~
	~~[[Category: Serpin~~]]

OCA at 09:07, 22 November 2017

2017-11-22T09:07:48Z

← Older revision		Revision as of 09:07, 22 November 2017
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	<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ROB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Anoga Anoga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SRPN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7165 ANOGA])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [http://pdbe.org/4rob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [http://www.ebi.ac.uk/pdbsum/4rob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [http://pdbe.org/4rob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [http://www.ebi.ac.uk/pdbsum/4rob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
	</table>		</table>

	~~==See Also==~~
	*[[Serpin\|Serpin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Anoga]]
	[[Category: An, C]]		[[Category: An, C]]
	[[Category: Battaile, K P]]		[[Category: Battaile, K P]]

OCA at 09:23, 4 August 2016

2016-08-04T09:23:28Z

← Older revision		Revision as of 09:23, 4 August 2016
Line 1:		Line 1:

	==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==		==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==
	<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ROB FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [http://www.ebi.ac.uk/pdbsum/4rob PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [http://pdbe.org/4rob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [http://www.ebi.ac.uk/pdbsum/4rob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
	</table>		</table>

			==See Also==
			*[[Serpin\|Serpin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:11, 24 December 2014

2014-12-24T11:11:06Z

← Older revision		Revision as of 11:11, 24 December 2014
Line 1:		Line 1:
	'''~~Unreleased structure~~'''		==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==
			<StructureSection load='4rob' size='340' side='right' caption='[[4rob]], [[Resolution\|resolution]] 2.80Å' scene=''>
	~~The entry~~ 4rob is ~~ON HOLD until Paper Publication~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
	~~Authors~~: ~~Lovell~~, S., ~~Battaile~~, K.P., ~~Zhang~~, X., Meekins, D.A~~., An, C.,~~ Michel, K.		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ro9\|4ro9]], [[4roa\|4roa]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [http://www.ebi.ac.uk/pdbsum/4rob PDBsum]</span></td></tr>
	~~Description~~: ~~2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae~~		</table>
			__TOC__
			</StructureSection>
			[[Category: An, C]]
			[[Category: Battaile, K P]]
			[[Category: Lovell, S]]
			[[Category: Meekins, D A]]
			[[Category: Michel, K]]
			[[Category: Zhang, X]]
			[[Category: Hydrolase inhibitor]]
			[[Category: Insect immunity]]
			[[Category: Serine protease inhibitor]]
			[[Category: Serpin]]

OCA at 11:27, 19 November 2014

2014-11-19T11:27:59Z

← Older revision		Revision as of 11:27, 19 November 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4rob is ON HOLD		The entry 4rob is ON HOLD until Paper Publication

	Authors: Lovell, ~~Scott~~, Battaile, ~~Kevin~~ P., Zhang, ~~Xin~~, Meekins, ~~David~~ A., An, ~~Chunju~~, Michel, ~~Kristin~~		Authors: Lovell, S., Battaile, K.P., Zhang, X., Meekins, D.A., An, C., Michel, K.

	Description: 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae		Description: 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae

OCA: Protected "4rob" [edit=sysop:move=sysop]

2014-11-05T07:41:39Z

Protected "4rob" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:41, 5 November 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4rob is ON HOLD Authors: Lovell, Scott, Battaile, Kevin P., Zhang, Xin, Meekins, David A., An, Chunju, Michel, Kristin Description: 2.8A resolution...

2014-11-05T07:41:38Z

New page: '''Unreleased structure''' The entry 4rob is ON HOLD Authors: Lovell, Scott, Battaile, Kevin P., Zhang, Xin, Meekins, David A., An, Chunju, Michel, Kristin Description: 2.8A resolution...

New page

'''Unreleased structure'''

The entry 4rob is ON HOLD

Authors: Lovell, Scott, Battaile, Kevin P., Zhang, Xin, Meekins, David A., An, Chunju, Michel, Kristin

Description: 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae