4tty - Revision history

OCA at 12:24, 20 December 2023

2023-12-20T12:24:41Z

← Older revision		Revision as of 12:24, 20 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TTY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TTY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [https://pdbe.org/4tty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [https://www.ebi.ac.uk/pdbsum/4tty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tty ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [https://pdbe.org/4tty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [https://www.ebi.ac.uk/pdbsum/4tty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tty ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 10:55, 15 March 2023

2023-03-15T10:55:44Z

← Older revision		Revision as of 10:55, 15 March 2023
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	<StructureSection load='4tty' size='340' side='right'caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4tty' size='340' side='right'caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chlre Chlre~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4TTY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TTY FirstGlance]. <br>
	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrSAS-6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [https://pdbe.org/4tty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [https://www.ebi.ac.uk/pdbsum/4tty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tty ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [~~http~~://pdbe.org/4tty PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4tty PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4tty ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/A9CQL4_CHLRE A9CQL4_CHLRE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Chlre~~]]		[[Category: Chlamydomonas reinhardtii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hilbert, M]]		[[Category: Hilbert M]]
	[[Category: Kraatz~~, S H.W]]~~		[[Category: Kraatz SHW]]
	~~[[Category: Alpha-beta protein]]~~
	~~[[Category: Beta-sandwich]]~~
	~~[[Category: Cartwheel]]~~
	~~[[Category: Centriole sas-6]]~~
	~~[[Category: Structural protein~~]]

OCA at 14:40, 10 May 2019

2019-05-10T14:40:21Z

← Older revision		Revision as of 14:40, 10 May 2019
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	==N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)==		==N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)==
	<StructureSection load='4tty' size='340' side='right' caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4tty' size='340' side='right'caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlre Chlre]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [http://pdbe.org/4tty PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [http://www.ebi.ac.uk/pdbsum/4tty PDBsum]</span></td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrSAS-6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3055 CHLRE])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [http://pdbe.org/4tty PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [http://www.ebi.ac.uk/pdbsum/4tty PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tty ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Chlre]]
			[[Category: Large Structures]]
	[[Category: Hilbert, M]]		[[Category: Hilbert, M]]
	[[Category: Kraatz, S H.W]]		[[Category: Kraatz, S H.W]]

OCA at 04:34, 11 May 2016

2016-05-11T04:34:24Z

← Older revision		Revision as of 04:34, 11 May 2016
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	==N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)==		==N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)==
	<StructureSection load='4tty' size='340' side='right' caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4tty' size='340' side='right' caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [http://www.ebi.ac.uk/pdbsum/4tty PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [http://pdbe.org/4tty PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [http://www.ebi.ac.uk/pdbsum/4tty PDBsum]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Centrioles are critical for the formation of centrosomes, cilia and flagella in eukaryotes. They are thought to assemble around a nine-fold symmetric cartwheel structure established by SAS-6 proteins. Here, we have engineered Chlamydomonas reinhardtii SAS-6-based oligomers with symmetries ranging from five- to ten-fold. Expression of a SAS-6 mutant that forms six-fold symmetric cartwheel structures in vitro resulted in cartwheels and centrioles with eight- or nine-fold symmetries in vivo. In combination with Bld10 mutants that weaken cartwheel-microtubule interactions, this SAS-6 mutant produced six- to eight-fold symmetric cartwheels. Concurrently, the microtubule wall maintained eight- and nine-fold symmetries. Expressing SAS-6 with analogous mutations in human cells resulted in nine-fold symmetric centrioles that exhibited impaired length and organization. Together, our data suggest that the self-assembly properties of SAS-6 instruct cartwheel symmetry, and lead us to propose a model in which the cartwheel and the microtubule wall assemble in an interdependent manner to establish the native architecture of centrioles.

			SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.,Hilbert M, Noga A, Frey D, Hamel V, Guichard P, Kraatz SH, Pfreundschuh M, Hosner S, Fluckiger I, Jaussi R, Wieser MM, Thieltges KM, Deupi X, Muller DJ, Kammerer RA, Gonczy P, Hirono M, Steinmetz MO Nat Cell Biol. 2016 Apr;18(4):393-403. doi: 10.1038/ncb3329. Epub 2016 Mar 21. PMID:26999736<ref>PMID:26999736</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 4tty" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:20, 1 July 2015

2015-07-01T12:20:59Z

← Older revision		Revision as of 12:20, 1 July 2015
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	'''~~Unreleased structure~~'''		==N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)==
			<StructureSection load='4tty' size='340' side='right' caption='[[4tty]], [[Resolution\|resolution]] 1.90Å' scene=''>
	~~The entry~~ 4tty is ~~ON HOLD until Paper Publication~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[4tty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TTY FirstGlance]. <br>
	~~Authors~~: ~~Hilbert, M~~.~~, Kraatz, S~~.H.W.		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tty OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tty RCSB], [http://www.ebi.ac.uk/pdbsum/4tty PDBsum]</span></td></tr>
			</table>
	~~Description~~:		__TOC__
	[[~~Category~~: ~~Unreleased Structures~~]]		</StructureSection>
	[~~[Category~~: ~~Kraatz, S~~.H.W]]
	[[Category: Hilbert, M]]		[[Category: Hilbert, M]]
			[[Category: Kraatz, S H.W]]
			[[Category: Alpha-beta protein]]
			[[Category: Beta-sandwich]]
			[[Category: Cartwheel]]
			[[Category: Centriole sas-6]]
			[[Category: Structural protein]]

OCA at 17:52, 24 December 2014

2014-12-24T17:52:22Z

← Older revision		Revision as of 17:52, 24 December 2014
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	Authors: Hilbert, M., Kraatz, S.H.W.		Authors: Hilbert, M., Kraatz, S.H.W.

	Description:		Description:
			[[Category: Unreleased Structures]]
			[[Category: Kraatz, S.H.W]]
			[[Category: Hilbert, M]]

OCA at 09:55, 16 July 2014

2014-07-16T09:55:44Z

← Older revision		Revision as of 09:55, 16 July 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 4tty is ON HOLD		The entry 4tty is ON HOLD until Paper Publication

	Authors: Hilbert, M., Kraatz, S.H.W.		Authors: Hilbert, M., Kraatz, S.H.W.

	Description:		Description:

OCA: Protected "4tty" [edit=sysop:move=sysop]

2014-07-02T07:33:57Z

Protected "4tty" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:33, 2 July 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4tty is ON HOLD Authors: Hilbert, M., Kraatz, S.H.W. Description:

2014-07-02T07:33:57Z

New page: '''Unreleased structure''' The entry 4tty is ON HOLD Authors: Hilbert, M., Kraatz, S.H.W. Description:

New page

'''Unreleased structure'''

The entry 4tty is ON HOLD

Authors: Hilbert, M., Kraatz, S.H.W.

Description: