4wp2 - Revision history

OCA at 07:19, 7 April 2023

2023-04-07T07:19:18Z

← Older revision		Revision as of 07:19, 7 April 2023
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	<StructureSection load='4wp2' size='340' side='right'caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4wp2' size='340' side='right'caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wp2 OCA], [~~http~~://pdbe.org/4wp2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wp2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wp2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wp2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wp2 OCA], [https://pdbe.org/4wp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wp2 RCSB], [https://www.ebi.ac.uk/pdbsum/4wp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wp2 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/G0SET4_CHATD G0SET4_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Aibara, S]]		[[Category: Aibara S]]
	[[Category: Stewart, M]]		[[Category: Stewart M]]
	~~[[Category: Nuclear export factor]]~~
	~~[[Category: Transport protein~~]]

OCA at 07:06, 10 July 2019

2019-07-10T07:06:41Z

← Older revision		Revision as of 07:06, 10 July 2019
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	==Chaetomium Mex67 UBA domain==		==Chaetomium Mex67 UBA domain==
	<StructureSection load='4wp2' size='340' side='right' caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4wp2' size='340' side='right'caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
	[[Category: Nuclear export factor]]		[[Category: Nuclear export factor]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 13:30, 19 April 2017

2017-04-19T13:30:25Z

← Older revision		Revision as of 13:30, 19 April 2017
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	==Chaetomium Mex67 UBA domain==		==Chaetomium Mex67 UBA domain==
	<StructureSection load='4wp2' size='340' side='right' caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='4wp2' size='340' side='right' caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>
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	<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wp2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wp2 OCA], [http://pdbe.org/4wp2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wp2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wp2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 4wp2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:26, 15 July 2015

2015-07-15T13:26:16Z

← Older revision		Revision as of 13:26, 15 July 2015
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	'''~~Unreleased~~ structure'''		==Chaetomium Mex67 UBA domain==
			<StructureSection load='4wp2' size='340' side='right' caption='[[4wp2]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[4wp2]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WP2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WP2 FirstGlance]. <br>
			</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wp2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wp2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wp2 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Members of the Mex67-Mtr2/NXF-NXT1 family are the principal mediators of the nuclear export of mRNA. Mex67/NXF1 has a modular structure based on four domains (RRM, LRR, NTF2-like and UBA) that are thought to be present across species, although the level of sequence conservation between organisms, especially in lower eukaryotes, is low. Here, the crystal structures of these domains from the thermophilic fungus Chaetomium thermophilum are presented together with small-angle X-ray scattering (SAXS) and in vitro RNA-binding data that indicate that, not withstanding the limited sequence conservation between different NXF family members, the molecules retain similar structural and RNA-binding properties. Moreover, the resolution of crystal structures obtained with the C. thermophilum domains was often higher than that obtained previously and, when combined with solution and biochemical studies, provided insight into the structural organization, self-association and RNA-binding properties of Mex67-Mtr2 that facilitate mRNA nuclear export.

	~~The entry 4wp2 is ON HOLD~~		Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.,Aibara S, Valkov E, Lamers MH, Dimitrova L, Hurt E, Stewart M Acta Crystallogr F Struct Biol Commun. 2015 Jul;71(Pt 7):876-88. doi:, 10.1107/S2053230X15008766. Epub 2015 Jun 27. PMID:26144233<ref>PMID:26144233</ref>

	~~Authors: Aibara~~, S.~~, Stewart, M~~.		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~Description: Chaetomium Mex67 UBA domain~~		== References ==
	~~[[Category: Unreleased Structures]]~~		<references/>
			__TOC__
			</StructureSection>
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]
			[[Category: Nuclear export factor]]
			[[Category: Transport protein]]

OCA at 19:48, 24 December 2014

2014-12-24T19:48:23Z

← Older revision		Revision as of 19:48, 24 December 2014
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	Description: Chaetomium Mex67 UBA domain		Description: Chaetomium Mex67 UBA domain
			[[Category: Unreleased Structures]]
			[[Category: Aibara, S]]
			[[Category: Stewart, M]]

OCA: Protected "4wp2" [edit=sysop:move=sysop]

2014-10-29T10:33:18Z

Protected "4wp2" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:33, 29 October 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 4wp2 is ON HOLD Authors: Aibara, S., Stewart, M. Description: Chaetomium Mex67 UBA domain

2014-10-29T10:33:17Z

New page: '''Unreleased structure''' The entry 4wp2 is ON HOLD Authors: Aibara, S., Stewart, M. Description: Chaetomium Mex67 UBA domain

New page

'''Unreleased structure'''

The entry 4wp2 is ON HOLD

Authors: Aibara, S., Stewart, M.

Description: Chaetomium Mex67 UBA domain