5dvm - Revision history

OCA at 22:01, 28 June 2023

2023-06-28T22:01:44Z

← Older revision		Revision as of 22:01, 28 June 2023
Line 3:		Line 3:
	<StructureSection load='5dvm' size='340' side='right'caption='[[5dvm]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='5dvm' size='340' side='right'caption='[[5dvm]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5DVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DVM FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.95Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">IGHG1 ([http://www.ncbi~~.~~nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5~~&~~id=9606 HUMAN])~~</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [https://pdbe.org/5dvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [https://www.ebi.ac.uk/pdbsum/5dvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dvm ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [~~http~~://pdbe.org/5dvm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5dvm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5dvm ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[~~[http~~://www.uniprot.org/uniprot/IGHG1_HUMAN IGHG1_HUMAN]] Defects in IGHG1 are a cause of multiple myeloma (MM) [MIM:[~~http~~://omim.org/entry/254500 254500]]. MM is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. Complications of multiple myeloma are bone pain, hypercalcemia, renal failure and spinal cord compression. The aberrant antibodies that are produced lead to impaired humoral immunity and patients have a high prevalence of infection. Amyloidosis may develop in some patients. Multiple myeloma is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. Note=A chromosomal aberration involving IGHG1 is found in multiple myeloma. Translocation t(11;14)(q13;q32) with the IgH locus. Translocation t(11;14)(q13;q32) with CCND1; translocation t(4;14)(p16.3;q32.3) with FGFR3; translocation t(6;14)(p25;q32) with IRF4.		[https://www.uniprot.org/uniprot/IGHG1_HUMAN IGHG1_HUMAN] Defects in IGHG1 are a cause of multiple myeloma (MM) [MIM:[https://omim.org/entry/254500 254500]. MM is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. Complications of multiple myeloma are bone pain, hypercalcemia, renal failure and spinal cord compression. The aberrant antibodies that are produced lead to impaired humoral immunity and patients have a high prevalence of infection. Amyloidosis may develop in some patients. Multiple myeloma is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. Note=A chromosomal aberration involving IGHG1 is found in multiple myeloma. Translocation t(11;14)(q13;q32) with the IgH locus. Translocation t(11;14)(q13;q32) with CCND1; translocation t(4;14)(p16.3;q32.3) with FGFR3; translocation t(6;14)(p25;q32) with IRF4.
			== Function ==
			[https://www.uniprot.org/uniprot/IGHG1_HUMAN IGHG1_HUMAN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Aldaz, H]]		[[Category: Synthetic construct]]
	[[Category: Atwell, S]]		[[Category: Aldaz H]]
	[[Category: Chamberlain~~, A K~~]]		[[Category: Atwell S]]
	[[Category: Demarest~~, S J~~]]		[[Category: Chamberlain AK]]
	[[Category: Dhanani~~, S H~~]]		[[Category: Demarest SJ]]
	[[Category: Fitchett~~, J R~~]]		[[Category: Dhanani SH]]
	[[Category: Froning~~, K J~~]]		[[Category: Fitchett JR]]
	[[Category: Gutierrez, B]]		[[Category: Froning KJ]]
	[[Category: Hendle, J]]		[[Category: Gutierrez B]]
	[[Category: Huang, F]]		[[Category: Hendle J]]
	[[Category: Kuhlman, B]]		[[Category: Huang F]]
	[[Category: Leaver-Fay, A]]		[[Category: Kuhlman B]]
	[[Category: Lu, F]]		[[Category: Leaver-Fay A]]
	[[Category: Pustilnik, A]]		[[Category: Lu F]]
	[[Category: Yuan, R]]		[[Category: Pustilnik A]]
	~~[[Category: Fc]]~~		[[Category: Yuan R]]
	~~[[Category: Head-to-tail homodimer]]~~
	~~[[Category: Immune system]]~~
	~~[[Category: Immunoglobulin~~]]

OCA at 08:09, 15 April 2020

2020-04-15T08:09:01Z

← Older revision		Revision as of 08:09, 15 April 2020
Line 1:		Line 1:

	==Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A==		==Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A==
	<StructureSection load='5dvm' size='340' side='right' caption='[[5dvm]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='5dvm' size='340' side='right'caption='[[5dvm]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=5DVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DVM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [http://pdbe.org/5dvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [http://www.ebi.ac.uk/pdbsum/5dvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dvm ProSAT]</span></td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IGHG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [http://pdbe.org/5dvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [http://www.ebi.ac.uk/pdbsum/5dvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dvm ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Aldaz, H]]		[[Category: Aldaz, H]]
	[[Category: Atwell, S]]		[[Category: Atwell, S]]

OCA at 17:19, 12 July 2016

2016-07-12T17:19:44Z

← Older revision		Revision as of 17:19, 12 July 2016
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DVM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [http://pdbe.org/5dvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [http://www.ebi.ac.uk/pdbsum/5dvm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [http://pdbe.org/5dvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [http://www.ebi.ac.uk/pdbsum/5dvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dvm ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==

OCA at 17:40, 10 May 2016

2016-05-10T17:40:08Z

← Older revision		Revision as of 17:40, 10 May 2016
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	The ~~entry 5dvm~~ is ~~ON HOLD until Paper~~ Publication		==Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A==
			<StructureSection load='5dvm' size='340' side='right' caption='[[5dvm]], [[Resolution\|resolution]] 2.95Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[5dvm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DVM FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5di8\|5di8]], [[5dj0\|5dj0]], [[5dj2\|5dj2]], [[5dj6\|5dj6]], [[5dj8\|5dj8]], [[5dja\|5dja]], [[5djc\|5djc]], [[5djd\|5djd]], [[5djx\|5djx]], [[5djy\|5djy]], [[5djz\|5djz]], [[5dk0\|5dk0]], [[5dk2\|5dk2]], [[5dvk\|5dvk]], [[5dvl\|5dvl]], [[5dvn\|5dvn]], [[5dvo\|5dvo]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dvm OCA], [http://pdbe.org/5dvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dvm RCSB], [http://www.ebi.ac.uk/pdbsum/5dvm PDBsum]</span></td></tr>
			</table>
			== Disease ==
			[[http://www.uniprot.org/uniprot/IGHG1_HUMAN IGHG1_HUMAN]] Defects in IGHG1 are a cause of multiple myeloma (MM) [MIM:[http://omim.org/entry/254500 254500]]. MM is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. Complications of multiple myeloma are bone pain, hypercalcemia, renal failure and spinal cord compression. The aberrant antibodies that are produced lead to impaired humoral immunity and patients have a high prevalence of infection. Amyloidosis may develop in some patients. Multiple myeloma is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. Note=A chromosomal aberration involving IGHG1 is found in multiple myeloma. Translocation t(11;14)(q13;q32) with the IgH locus. Translocation t(11;14)(q13;q32) with CCND1; translocation t(4;14)(p16.3;q32.3) with FGFR3; translocation t(6;14)(p25;q32) with IRF4.
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			A challenge in the structure-based design of specificity is modeling the negative states, i.e., the complexes that you do not want to form. This is a difficult problem because mutations predicted to destabilize the negative state might be accommodated by small conformational rearrangements. To overcome this challenge, we employ an iterative strategy that cycles between sequence design and protein docking in order to build up an ensemble of alternative negative state conformations for use in specificity prediction. We have applied our technique to the design of heterodimeric CH3 interfaces in the Fc region of antibodies. Combining computationally and rationally designed mutations produced unique designs with heterodimer purities greater than 90%. Asymmetric Fc crystallization was able to resolve the interface mutations; the heterodimer structures confirmed that the interfaces formed as designed. With these CH3 mutations, and those made at the heavy-/light-chain interface, we demonstrate one-step synthesis of four fully IgG-bispecific antibodies.

	~~Authors: Atwell, S~~., Leaver-Fay, A., Froning, ~~K.J.~~, Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R~~., Dhanani~~, S~~.H.~~, Chamberlain, A.K.~~, Fitchett, J~~.R.~~, Gutierrez, B~~.~~, Hendle, J~~.~~, Demarest, S~~.J., ~~Kuhlman, B~~.		Computationally Designed Bispecific Antibodies using Negative State Repertoires.,Leaver-Fay A, Froning KJ, Atwell S, Aldaz H, Pustilnik A, Lu F, Huang F, Yuan R, Hassanali S, Chamberlain AK, Fitchett JR, Demarest SJ, Kuhlman B Structure. 2016 Apr 5;24(4):641-51. doi: 10.1016/j.str.2016.02.013. Epub 2016 Mar, 17. PMID:26996964<ref>PMID:26996964</ref>

	~~Description: Fc Design 20~~.8.~~37 B chain homodimer E357D~~/~~S364R~~/~~Y407A~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[Category: Unreleased Structures]]~~		</div>
	~~[[Category: Leaver-Fay, A]]~~		<div class="pdbe-citations 5dvm" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Aldaz, H]]		[[Category: Aldaz, H]]
			[[Category: Atwell, S]]
			[[Category: Chamberlain, A K]]
			[[Category: Demarest, S J]]
			[[Category: Dhanani, S H]]
			[[Category: Fitchett, J R]]
			[[Category: Froning, K J]]
	[[Category: Gutierrez, B]]		[[Category: Gutierrez, B]]
	[[Category: ~~Fitchett~~, J.R]]		[[Category: Hendle, J]]
	[[Category: ~~Dhanani~~, ~~S.H~~]]		[[Category: Huang, F]]
	[[Category: Kuhlman, B]]		[[Category: Kuhlman, B]]
	[[Category: ~~Froning~~, ~~K.J]]~~		[[Category: Leaver-Fay, A]]
	~~[[Category: Demarest, S.J]]~~
	~~[[Category: Atwell, S]]~~
	~~[[Category: Hendle, J]]~~
	~~[[Category: Yuan, R~~]]
	[[Category: Lu, F]]		[[Category: Lu, F]]
	~~[[Category: Huang, F]]~~
	~~[[Category: Chamberlain, A.K]]~~
	[[Category: Pustilnik, A]]		[[Category: Pustilnik, A]]
			[[Category: Yuan, R]]
			[[Category: Fc]]
			[[Category: Head-to-tail homodimer]]
			[[Category: Immune system]]
			[[Category: Immunoglobulin]]

OCA at 11:27, 16 December 2015

2015-12-16T11:27:28Z

← Older revision		Revision as of 11:27, 16 December 2015
Line 7:		Line 7:
	Description: Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A		Description: Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Leaver-Fay, A]]
			[[Category: Aldaz, H]]
			[[Category: Gutierrez, B]]
	[[Category: Fitchett, J.R]]		[[Category: Fitchett, J.R]]
	[[Category: Dhanani, S.H]]		[[Category: Dhanani, S.H]]
Line 12:		Line 15:
	[[Category: Froning, K.J]]		[[Category: Froning, K.J]]
	[[Category: Demarest, S.J]]		[[Category: Demarest, S.J]]
	~~[[Category: Yuan, R]]~~
	~~[[Category: Leaver-Fay, A]]~~
	~~[[Category: Aldaz, H]]~~
	~~[[Category: Gutierrez, B]]~~
	[[Category: Atwell, S]]		[[Category: Atwell, S]]
	[[Category: Hendle, J]]		[[Category: Hendle, J]]
			[[Category: Yuan, R]]
	[[Category: Lu, F]]		[[Category: Lu, F]]
	[[Category: Huang, F]]		[[Category: Huang, F]]
	[[Category: Chamberlain, A.K]]		[[Category: Chamberlain, A.K]]
	[[Category: Pustilnik, A]]		[[Category: Pustilnik, A]]

OCA at 02:12, 1 December 2015

2015-12-01T02:12:57Z

← Older revision		Revision as of 02:12, 1 December 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 5dvm is ON HOLD		The entry 5dvm is ON HOLD until Paper Publication

	Authors: Atwell, S., Leaver-Fay, A., Froning, K.J., Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R., Dhanani, S.H., Chamberlain, A.K., Fitchett, J.R., Gutierrez, B., Hendle, J., Demarest, S.J., Kuhlman, B.		Authors: Atwell, S., Leaver-Fay, A., Froning, K.J., Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R., Dhanani, S.H., Chamberlain, A.K., Fitchett, J.R., Gutierrez, B., Hendle, J., Demarest, S.J., Kuhlman, B.

OCA: Protected "5dvm" [edit=sysop:move=sysop]

2015-09-30T13:35:42Z

Protected "5dvm" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:35, 30 September 2015
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5dvm is ON HOLD Authors: Atwell, S., Leaver-Fay, A., Froning, K.J., Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R., Dhanani, S.H., Chamberlai...

2015-09-30T13:35:41Z

New page: '''Unreleased structure''' The entry 5dvm is ON HOLD Authors: Atwell, S., Leaver-Fay, A., Froning, K.J., Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R., Dhanani, S.H., Chamberlai...

New page

'''Unreleased structure'''

The entry 5dvm is ON HOLD

Authors: Atwell, S., Leaver-Fay, A., Froning, K.J., Aldaz, H., Pustilnik, A., Lu, F., Huang, F., Yuan, R., Dhanani, S.H., Chamberlain, A.K., Fitchett, J.R., Gutierrez, B., Hendle, J., Demarest, S.J., Kuhlman, B.

Description: Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A
[[Category: Unreleased Structures]]
[[Category: Fitchett, J.R]]
[[Category: Dhanani, S.H]]
[[Category: Kuhlman, B]]
[[Category: Froning, K.J]]
[[Category: Demarest, S.J]]
[[Category: Yuan, R]]
[[Category: Leaver-Fay, A]]
[[Category: Aldaz, H]]
[[Category: Gutierrez, B]]
[[Category: Atwell, S]]
[[Category: Hendle, J]]
[[Category: Lu, F]]
[[Category: Huang, F]]
[[Category: Chamberlain, A.K]]
[[Category: Pustilnik, A]]