5fun - Revision history

OCA at 13:27, 26 July 2023

2023-07-26T13:27:21Z

← Older revision		Revision as of 13:27, 26 July 2023
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	<StructureSection load='5fun' size='340' side='right'caption='[[5fun]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5fun' size='340' side='right'caption='[[5fun]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5FUN FirstGlance]. <br>		<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FUN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [~~http~~://pdbe.org/5fun PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fun PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fun ProSAT]</span></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [https://pdbe.org/5fun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [https://www.ebi.ac.uk/pdbsum/5fun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fun ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/KDM5B_HUMAN KDM5B_HUMAN]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.<ref>PMID:12657635</ref> <ref>PMID:16645588</ref> <ref>PMID:17320161</ref> <ref>PMID:17363312</ref>		[https://www.uniprot.org/uniprot/KDM5B_HUMAN KDM5B_HUMAN] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.<ref>PMID:12657635</ref> <ref>PMID:16645588</ref> <ref>PMID:17320161</ref> <ref>PMID:17363312</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arrowsmith~~, C H~~]]		[[Category: Arrowsmith CH]]
	[[Category: Bountra, C]]		[[Category: Bountra C]]
	[[Category: Brennan, P]]		[[Category: Brennan P]]
	~~[[Category: Delft, F von~~]]		[[Category: Edwards A]]
	[[Category: Edwards, A]]		[[Category: Gileadi C]]
	[[Category: Gileadi, C]]		[[Category: Johansson C]]
	[[Category: Johansson, C]]		[[Category: Kopec J]]
	[[Category: Kopec, J]]		[[Category: Oppermann U]]
	[[Category: Oppermann, U]]		[[Category: Srikannathasan V]]
	[[Category: Srikannathasan, V]]		[[Category: Von Delft F]]
	[[Category: ~~Lysine-specific demethylase 5b]]~~
	~~[[Category: Oxidoreductase~~]]

OCA at 07:38, 6 May 2020

2020-05-06T07:38:15Z

← Older revision		Revision as of 07:38, 6 May 2020
Line 1:		Line 1:

	==Crystal structure of human JARID1B in complex with GSK467==		==Crystal structure of human JARID1B in complex with GSK467==
	<StructureSection load='5fun' size='340' side='right' caption='[[5fun]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5fun' size='340' side='right'caption='[[5fun]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=5FUN FirstGlance]. <br>		<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FUN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [http://pdbe.org/5fun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [http://www.ebi.ac.uk/pdbsum/5fun PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fun ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [http://pdbe.org/5fun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [http://www.ebi.ac.uk/pdbsum/5fun PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fun ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5fun" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5fun" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Jumonji domain-containing protein 3D structures\|Jumonji domain-containing protein 3D structures]]
			*[[Lysine-specific histone demethylase 3D structures\|Lysine-specific histone demethylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 17:12, 12 July 2016

2016-07-12T17:12:29Z

← Older revision		Revision as of 17:12, 12 July 2016
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FUN FirstGlance]. <br>		<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FUN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [http://pdbe.org/5fun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [http://www.ebi.ac.uk/pdbsum/5fun PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [http://pdbe.org/5fun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [http://www.ebi.ac.uk/pdbsum/5fun PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fun ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:05, 1 June 2016

2016-06-01T08:05:17Z

← Older revision		Revision as of 08:05, 1 June 2016
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/KDM5B_HUMAN KDM5B_HUMAN]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.<ref>PMID:12657635</ref> <ref>PMID:16645588</ref> <ref>PMID:17320161</ref> <ref>PMID:17363312</ref>		[[http://www.uniprot.org/uniprot/KDM5B_HUMAN KDM5B_HUMAN]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.<ref>PMID:12657635</ref> <ref>PMID:16645588</ref> <ref>PMID:17320161</ref> <ref>PMID:17363312</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Members of the KDM5 (also known as JARID1) family are 2-oxoglutarate- and Fe2+-dependent oxygenases that act as histone H3K4 demethylases, thereby regulating cell proliferation and stem cell self-renewal and differentiation. Here we report crystal structures of the catalytic core of the human KDM5B enzyme in complex with three inhibitor chemotypes. These scaffolds exploit several aspects of the KDM5 active site, and their selectivity profiles reflect their hybrid features with respect to the KDM4 and KDM6 families. Whereas GSK-J1, a previously identified KDM6 inhibitor, showed about sevenfold less inhibitory activity toward KDM5B than toward KDM6 proteins, KDM5-C49 displayed 25-100-fold selectivity between KDM5B and KDM6B. The cell-permeable derivative KDM5-C70 had an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels. The selective inhibitor GSK467 exploited unique binding modes, but it lacked cellular potency in the myeloma system. Taken together, these structural leads deliver multiple starting points for further rational and selective inhibitor design.

			Structural analysis of human KDM5B guides histone demethylase inhibitor development.,Johansson C, Velupillai S, Tumber A, Szykowska A, Hookway ES, Nowak RP, Strain-Damerell C, Gileadi C, Philpott M, Burgess-Brown N, Wu N, Kopec J, Nuzzi A, Steuber H, Egner U, Badock V, Munro S, LaThangue NB, Westaway S, Brown J, Athanasou N, Prinjha R, Brennan PE, Oppermann U Nat Chem Biol. 2016 May 23. doi: 10.1038/nchembio.2087. PMID:27214403<ref>PMID:27214403</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 5fun" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:27, 12 May 2016

2016-05-12T11:27:26Z

← Older revision		Revision as of 11:27, 12 May 2016
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 5fun ~~is ON HOLD~~		==Crystal structure of human JARID1B in complex with GSK467==
			<StructureSection load='5fun' size='340' side='right' caption='[[5fun]], [[Resolution\|resolution]] 2.30Å' scene=''>
	~~Authors~~: ~~Srikannathasan, V~~., ~~Johansson~~, C., ~~Gileadi~~, C., ~~Kopec~~, J., ~~von Delft~~, F., ~~Arrowsmith, C~~.H., ~~Bountra~~, C., ~~Edwards~~, A., ~~Brennan, P~~., ~~Oppermann, U~~.		== Structural highlights ==
			<table><tr><td colspan='2'>[[5fun]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FUN FirstGlance]. <br>
	~~Description: Crystal structure of human JARID1B in complex with GSK467~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GZA:2-[(1-BENZYL-1H-PYRAZOL-4-YL)OXY]PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE'>GZA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fun OCA], [http://pdbe.org/5fun PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fun RCSB], [http://www.ebi.ac.uk/pdbsum/5fun PDBsum]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/KDM5B_HUMAN KDM5B_HUMAN]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.<ref>PMID:12657635</ref> <ref>PMID:16645588</ref> <ref>PMID:17320161</ref> <ref>PMID:17363312</ref>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
			[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]
	[[Category: ~~Arrowsmith~~, ~~C.H~~]]		[[Category: Brennan, P]]
			[[Category: Delft, F von]]
			[[Category: Edwards, A]]
	[[Category: Gileadi, C]]		[[Category: Gileadi, C]]
			[[Category: Johansson, C]]
			[[Category: Kopec, J]]
	[[Category: Oppermann, U]]		[[Category: Oppermann, U]]
	~~[[Category: Kopec, J]]~~
	~~[[Category: Von Delft, F]]~~
	~~[[Category: Johansson, C]]~~
	~~[[Category: Edwards, A]]~~
	~~[[Category: Brennan, P]]~~
	[[Category: Srikannathasan, V]]		[[Category: Srikannathasan, V]]
			[[Category: Lysine-specific demethylase 5b]]
			[[Category: Oxidoreductase]]

OCA: Protected "5fun" [edit=sysop:move=sysop]

2016-02-03T13:28:25Z

Protected "5fun" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:28, 3 February 2016
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5fun is ON HOLD Authors: Srikannathasan, V., Johansson, C., Gileadi, C., Kopec, J., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Brenn...

2016-02-03T13:28:23Z

New page: '''Unreleased structure''' The entry 5fun is ON HOLD Authors: Srikannathasan, V., Johansson, C., Gileadi, C., Kopec, J., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Brenn...

New page

'''Unreleased structure'''

The entry 5fun is ON HOLD

Authors: Srikannathasan, V., Johansson, C., Gileadi, C., Kopec, J., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Brennan, P., Oppermann, U.

Description: Crystal structure of human JARID1B in complex with GSK467
[[Category: Unreleased Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith, C.H]]
[[Category: Gileadi, C]]
[[Category: Oppermann, U]]
[[Category: Kopec, J]]
[[Category: Von Delft, F]]
[[Category: Johansson, C]]
[[Category: Edwards, A]]
[[Category: Brennan, P]]
[[Category: Srikannathasan, V]]