5ith - Revision history

OCA at 14:08, 30 August 2023

2023-08-30T14:08:55Z

← Older revision		Revision as of 14:08, 30 August 2023
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	<StructureSection load='5ith' size='340' side='right'caption='[[5ith]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='5ith' size='340' side='right'caption='[[5ith]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5ITH FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ITH FirstGlance]. <br>
	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~TIA1 (~~[~~http://www.ncbi.nlm~~.~~nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5~~&~~id=9606 HUMAN])~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.31Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [~~http~~://pdbe.org/5ith PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ith PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [https://pdbe.org/5ith PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [https://www.ebi.ac.uk/pdbsum/5ith PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.		[https://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Waris, S]]		[[Category: Waris S]]
	[[Category: Wilce~~, J A~~]]		[[Category: Wilce JA]]
	[[Category: Wilce~~, M C]]~~		[[Category: Wilce MC]]
	~~[[Category: Aromatic base stacking interaction]]~~
	~~[[Category: Dna binding protein-dna complex]]~~
	~~[[Category: Poly u binding preference]]~~
	~~[[Category: Rna binding protein-dna complex]]~~
	~~[[Category: Rna/dna binding domain]]~~
	~~[[Category: Rrm~~]]

OCA at 07:31, 3 June 2020

2020-06-03T07:31:11Z

← Older revision		Revision as of 07:31, 3 June 2020
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	==TIA-1 RRM2 recognition of target oligonucleotide==		==TIA-1 RRM2 recognition of target oligonucleotide==
	<StructureSection load='5ith' size='340' side='right' caption='[[5ith]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='5ith' size='340' side='right'caption='[[5ith]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=5ITH FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ITH FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TIA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Waris, S]]		[[Category: Waris, S]]
	[[Category: Wilce, J A]]		[[Category: Wilce, J A]]

OCA at 09:06, 17 May 2017

2017-05-17T09:06:36Z

@@ Line 8: / Line 8: @@
 == Function ==
 [[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
 __TOC__
 </StructureSection>

OCA at 01:34, 11 March 2017

2017-03-11T01:34:55Z

← Older revision		Revision as of 01:34, 11 March 2017
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	~~'''Unreleased structure'''~~

	~~The entry~~ 5ith is ~~ON HOLD until Mar 16 2018~~		==TIA-1 RRM2 recognition of target oligonucleotide==
			<StructureSection load='5ith' size='340' side='right' caption='[[5ith]], [[Resolution\|resolution]] 2.31Å' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITH FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
			__TOC__
			</StructureSection>
			[[Category: Waris, S]]
			[[Category: Wilce, J A]]
			[[Category: Wilce, M C]]
			[[Category: Aromatic base stacking interaction]]
			[[Category: Dna binding protein-dna complex]]
			[[Category: Poly u binding preference]]
			[[Category: Rna binding protein-dna complex]]
			[[Category: Rna/dna binding domain]]
			[[Category: Rrm]]

OCA at 14:43, 15 May 2016

2016-05-15T14:43:27Z

← Older revision		Revision as of 14:43, 15 May 2016
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	The entry 5ith is ON HOLD until Mar 16 2018		The entry 5ith is ON HOLD until Mar 16 2018

	Authors: ~~Waris, S., Wilce, J.A., Wilce, M.C.~~		Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Wilce, J.A]]~~
	~~[[Category: Wilce, M.C]]~~
	~~[[Category: Waris, S]]~~

OCA: Protected "5ith" [edit=sysop:move=sysop]

2016-05-11T00:55:04Z

Protected "5ith" [edit=sysop:move=sysop]

← Older revision	Revision as of 00:55, 11 May 2016
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5ith is ON HOLD until Mar 16 2018 Authors: Waris, S., Wilce, J.A., Wilce, M.C. Description: Category: Unreleased Structures [[Category: Wilce,...

2016-05-11T00:55:03Z

New page: '''Unreleased structure''' The entry 5ith is ON HOLD until Mar 16 2018 Authors: Waris, S., Wilce, J.A., Wilce, M.C. Description: Category: Unreleased Structures [[Category: Wilce,...

New page

'''Unreleased structure'''

The entry 5ith is ON HOLD until Mar 16 2018

Authors: Waris, S., Wilce, J.A., Wilce, M.C.

Description:
[[Category: Unreleased Structures]]
[[Category: Wilce, J.A]]
[[Category: Wilce, M.C]]
[[Category: Waris, S]]