5lev - Revision history

OCA at 08:57, 11 October 2023

2023-10-11T08:57:56Z

← Older revision		Revision as of 08:57, 11 October 2023
Line 3:		Line 3:
	<StructureSection load='5lev' size='340' side='right'caption='[[5lev]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='5lev' size='340' side='right'caption='[[5lev]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5LEV FirstGlance]. <br>		<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LEV FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">DPAGT1, DPAGT2 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5~~&~~id=9606 HUMAN])~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </~~span~~></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [https://pdbe.org/5lev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [https://www.ebi.ac.uk/pdbsum/5lev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [~~http~~://pdbe.org/5lev PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5lev PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[~~[http~~://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.		[https://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.		[https://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]]~~		[[Category: Arrowsmith CH]]
	[[Category: Arrowsmith~~, C H~~]]		[[Category: Beeson D]]
	[[Category: Beeson, D]]		[[Category: Belaya K]]
	[[Category: Belaya, K]]		[[Category: Berridge G]]
	[[Category: Berridge, G]]		[[Category: Bountra C]]
	[[Category: Bountra, C]]		[[Category: Burgess-Brown N]]
	[[Category: Burgess-Brown, N]]		[[Category: Carpenter EP]]
	[[Category: Carpenter~~, E P~~]]		[[Category: Chalk R]]
	[[Category: Chalk, R]]		[[Category: Chu A]]
	[[Category: Chu, A]]		[[Category: Dong L]]
	[[Category: Dong, L]]		[[Category: Dong YY]]
	[[Category: Dong~~, Y Y~~]]		[[Category: Edwards AM]]
	[[Category: Edwards~~, A M~~]]		[[Category: Goubin S]]
	[[Category: Goubin, S]]		[[Category: Kupinska K]]
	[[Category: Kupinska, K]]		[[Category: Mahajan P]]
	[[Category: Mahajan, P]]		[[Category: Mukhopadhyay S]]
	[[Category: Mukhopadhyay, S]]		[[Category: Pike ACW]]
	[[Category: Pike~~, A C.W]]~~		[[Category: Tessitore A]]
	~~[[Category: Structural genomic~~]]		[[Category: Wang D]]
	[[Category: Tessitore, A]]
	[[Category: Wang, D]]
	~~[[Category: Congenital myasthenic syndrome 13]]~~
	~~[[Category: Integral membrane protein]]~~
	~~[[Category: Protein glycosylation]]~~
	~~[[Category: Sgc]]~~
	~~[[Category: Transferase~~]]

OCA at 16:33, 20 November 2019

2019-11-20T16:33:25Z

← Older revision		Revision as of 16:33, 20 November 2019
Line 1:		Line 1:

	==Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)==		==Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)==
	<StructureSection load='5lev' size='340' side='right' caption='[[5lev]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='5lev' size='340' side='right'caption='[[5lev]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LEV FirstGlance]. <br>		<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LEV FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DPAGT1, DPAGT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [http://pdbe.org/5lev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [http://www.ebi.ac.uk/pdbsum/5lev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [http://pdbe.org/5lev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [http://www.ebi.ac.uk/pdbsum/5lev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>
Line 12:		Line 13:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.		[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Protein N-glycosylation is a widespread post-translational modification. The first committed step in this process is catalysed by dolichyl-phosphate N-acetylglucosamine-phosphotransferase DPAGT1 (GPT/E.C. 2.7.8.15). Missense DPAGT1 variants cause congenital myasthenic syndrome and disorders of glycosylation. In addition, naturally-occurring bactericidal nucleoside analogues such as tunicamycin are toxic to eukaryotes due to DPAGT1 inhibition, preventing their clinical use. Our structures of DPAGT1 with the substrate UDP-GlcNAc and tunicamycin reveal substrate binding modes, suggest a mechanism of catalysis, provide an understanding of how mutations modulate activity (thus causing disease) and allow design of non-toxic "lipid-altered" tunicamycins. The structure-tuned activity of these analogues against several bacterial targets allowed the design of potent antibiotics for Mycobacterium tuberculosis, enabling treatment in vitro, in cellulo and in vivo, providing a promising new class of antimicrobial drug.

			Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.,Dong YY, Wang H, Pike ACW, Cochrane SA, Hamedzadeh S, Wyszynski FJ, Bushell SR, Royer SF, Widdick DA, Sajid A, Boshoff HI, Park Y, Lucas R, Liu WM, Lee SS, Machida T, Minall L, Mehmood S, Belaya K, Liu WW, Chu A, Shrestha L, Mukhopadhyay SMM, Strain-Damerell C, Chalk R, Burgess-Brown NA, Bibb MJ, Barry Iii CE, Robinson CV, Beeson D, Davis BG, Carpenter EP Cell. 2018 Nov 1;175(4):1045-1058.e16. doi: 10.1016/j.cell.2018.10.037. PMID:30388443<ref>PMID:30388443</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 5lev" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]]		[[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]

OCA at 16:25, 2 January 2017

2017-01-02T16:25:52Z

← Older revision		Revision as of 16:25, 2 January 2017
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 5lev is ~~ON HOLD until Aug 25 2017~~		==Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)==
			<StructureSection load='5lev' size='340' side='right' caption='[[5lev]], [[Resolution\|resolution]] 3.20Å' scene=''>
	~~Authors~~: ~~Pike~~, A.C.W.~~, Dong, Y~~.Y.~~, Chu, A~~., ~~Tessitore, A~~.~~, Goubin, S~~.~~, Dong, L~~., ~~Mukhopadhyay, S~~., ~~Mahajan, P~~.~~, Chalk, R~~.~~, Berridge, G~~., ~~Wang, D~~.~~, Kupinska, K~~.~~, Belaya, K~~., ~~Beeson, D~~.~~, Burgess~~-~~Brown, N~~.~~, Edwards, A~~.M.~~, Arrowsmith, C~~.H.~~, Bountra, C~~.~~, Carpenter, E~~.P.~~, Structural Genomics Consortium (SGC)~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LEV FirstGlance]. <br>
	~~Description~~: ~~Crystal structure of human~~ UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase ~~(DPAGT1) (V264G mutant)(CASP target)~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr>
	[[Category: ~~Goubin~~, S]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [http://pdbe.org/5lev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [http://www.ebi.ac.uk/pdbsum/5lev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>
	[[Category: ~~Pike~~, A.C.W]]		</table>
			== Disease ==
			[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
			== Function ==
			[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
			__TOC__
			</StructureSection>
			[[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]]
			[[Category: Arrowsmith, C H]]
			[[Category: Beeson, D]]
			[[Category: Belaya, K]]
			[[Category: Berridge, G]]
			[[Category: Bountra, C]]
	[[Category: Burgess-Brown, N]]		[[Category: Burgess-Brown, N]]
	[[Category: ~~Wang~~, D]]		[[Category: Carpenter, E P]]
			[[Category: Chalk, R]]
	[[Category: Chu, A]]		[[Category: Chu, A]]
	[[Category: ~~Mukhopadhyay~~, S]]		[[Category: Dong, L]]
	[[Category: ~~Berridge~~, G]]		[[Category: Dong, Y Y]]
	[[Category: ~~Carpenter~~, ~~E.P~~]]		[[Category: Edwards, A M]]
	[[Category: ~~Bountra~~, C]]		[[Category: Goubin, S]]
	[[Category: Kupinska, K]]		[[Category: Kupinska, K]]
	~~[[Category: Dong, L]]~~
	~~[[Category: Arrowsmith, C.H]]~~
	~~[[Category: Chalk, R]]~~
	~~[[Category: Dong, Y.Y]]~~
	[[Category: Mahajan, P]]		[[Category: Mahajan, P]]
			[[Category: Mukhopadhyay, S]]
			[[Category: Pike, A C.W]]
			[[Category: Structural genomic]]
	[[Category: Tessitore, A]]		[[Category: Tessitore, A]]
	[[Category: ~~Edwards~~, ~~A.M~~]]		[[Category: Wang, D]]
	[[Category: ~~Structural Genomics Consortium (Sgc)~~]]		[[Category: Congenital myasthenic syndrome 13]]
	[[Category: ~~Beeson, D~~]]		[[Category: Integral membrane protein]]
	[[Category: ~~Belaya, K~~]]		[[Category: Protein glycosylation]]
			[[Category: Sgc]]
			[[Category: Transferase]]

OCA at 18:05, 22 December 2016

2016-12-22T18:05:54Z

← Older revision		Revision as of 18:05, 22 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 5lev is ON HOLD		The entry 5lev is ON HOLD until Aug 25 2017

	Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)		Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

OCA: Protected "5lev" [edit=sysop:move=sysop]

2016-07-13T01:04:33Z

Protected "5lev" [edit=sysop:move=sysop]

← Older revision	Revision as of 01:04, 13 July 2016
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5lev is ON HOLD Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge,...

2016-07-13T01:04:31Z

New page: '''Unreleased structure''' The entry 5lev is ON HOLD Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge,...

New page

'''Unreleased structure'''

The entry 5lev is ON HOLD

Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)

Description: Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)(CASP target)
[[Category: Unreleased Structures]]
[[Category: Goubin, S]]
[[Category: Pike, A.C.W]]
[[Category: Burgess-Brown, N]]
[[Category: Wang, D]]
[[Category: Chu, A]]
[[Category: Mukhopadhyay, S]]
[[Category: Berridge, G]]
[[Category: Carpenter, E.P]]
[[Category: Bountra, C]]
[[Category: Kupinska, K]]
[[Category: Dong, L]]
[[Category: Arrowsmith, C.H]]
[[Category: Chalk, R]]
[[Category: Dong, Y.Y]]
[[Category: Mahajan, P]]
[[Category: Tessitore, A]]
[[Category: Edwards, A.M]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Beeson, D]]
[[Category: Belaya, K]]