5toe - Revision history

OCA at 14:22, 6 March 2024

2024-03-06T14:22:40Z

← Older revision		Revision as of 14:22, 6 March 2024
Line 3:		Line 3:
	<StructureSection load='5toe' size='340' side='right'caption='[[5toe]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5toe' size='340' side='right'caption='[[5toe]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5toe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TOE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5TOE FirstGlance]. <br>		<table><tr><td colspan='2'>[[5toe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TOE FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=7GK:2~~-[~~4-(piperazin-1-yl)phenyl~~]~~-1H-pyrrolo[~~2~~,3-b]pyridine-4-carbonitrile'>7GK</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.301Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>~~[~~http://en.wikipedia.org/wiki/Non~~-~~specific_serine/threonine_protein_kinase Non~~-~~specific serine/threonine protein kinase~~], ~~with EC number [http://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1~~] </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GK:2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile'>7GK</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5toe OCA], [~~http~~://pdbe.org/5toe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5toe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5toe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5toe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5toe OCA], [https://pdbe.org/5toe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5toe RCSB], [https://www.ebi.ac.uk/pdbsum/5toe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5toe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/PIM1_HUMAN PIM1_HUMAN]] Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis. Mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X(L)/BCL2L1. Phosphorylation of MAP3K5, an other proapoptotic protein, by PIM1, significantly decreases MAP3K5 kinase activity and inhibits MAP3K5-mediated phosphorylation of JNK and JNK/p38MAPK subsequently reducing caspase-3 activation and cell apoptosis. Stimulates cell cycle progression at the G1-S and G2-M transitions by phosphorylation of CDC25A and CDC25C. Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of CDKN1A to the cytoplasm and enhanced CDKN1A protein stability. Promote cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression, CDKN1B, at both transcriptional and post-translational levels. Phosphorylation of CDKN1B,induces 14-3-3-proteins binding, nuclear export and proteasome-dependent degradation. May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Acts also as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.<ref>PMID:1825810</ref> <ref>PMID:10664448</ref> <ref>PMID:12431783</ref> <ref>PMID:15528381</ref> <ref>PMID:16356754</ref> <ref>PMID:18593906</ref> <ref>PMID:19749799</ref>		[https://www.uniprot.org/uniprot/PIM1_HUMAN PIM1_HUMAN] Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis. Mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X(L)/BCL2L1. Phosphorylation of MAP3K5, an other proapoptotic protein, by PIM1, significantly decreases MAP3K5 kinase activity and inhibits MAP3K5-mediated phosphorylation of JNK and JNK/p38MAPK subsequently reducing caspase-3 activation and cell apoptosis. Stimulates cell cycle progression at the G1-S and G2-M transitions by phosphorylation of CDC25A and CDC25C. Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of CDKN1A to the cytoplasm and enhanced CDKN1A protein stability. Promote cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression, CDKN1B, at both transcriptional and post-translational levels. Phosphorylation of CDKN1B,induces 14-3-3-proteins binding, nuclear export and proteasome-dependent degradation. May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Acts also as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.<ref>PMID:1825810</ref> <ref>PMID:10664448</ref> <ref>PMID:12431783</ref> <ref>PMID:15528381</ref> <ref>PMID:16356754</ref> <ref>PMID:18593906</ref> <ref>PMID:19749799</ref>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Novel N-substituted azaindoles have been discovered as PIM1 inhibitors. X-ray structures have played a significant role in orienting the chemistry effort in the initial phase of hit confirmation. Disclosure of an unconventional binding mode for 1 and 2, as demonstrated by X-ray crystallography, is presented and was an important factor in selecting and advancing a lead series.

	Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.,Barberis C, Moorcroft N, Arendt C, Levit M, Moreno-Mazza S, Batchelor J, Mechin I, Majid T Bioorg Med Chem Lett. 2017 Oct 15;27(20):4730-4734. doi:, 10.1016/j.bmcl.2017.08.069. Epub 2017 Sep 18. PMID:28947155<ref>PMID:28947155</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 5toe" style="background-color:#fffaf0;"></div~~>

	==See Also==		==See Also==
	*[[Proto-oncogene serine/threonine-protein kinase\|Proto-oncogene serine/threonine-protein kinase]]
	*[[Serine/threonine protein kinase 3D structures\|Serine/threonine protein kinase 3D structures]]		*[[Serine/threonine protein kinase 3D structures\|Serine/threonine protein kinase 3D structures]]
			*[[3D structures of pim-1\|3D structures of pim-1]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Non-specific serine/threonine protein kinase]]~~		[[Category: Batchelor JD]]
	[[Category: Batchelor~~, J D~~]]		[[Category: Mclean L]]
	[[Category: Mclean, L]]		[[Category: Mechin I]]
	[[Category: Mechin, I]]		[[Category: Wang R]]
	[[Category: Wang, R]]		[[Category: Zhang Y]]
	[[Category: Zhang, Y]]
	~~[[Category: Inhibitor]]~~
	~~[[Category: Kinase]]~~
	~~[[Category: Transferase-transferase inhibitor complex~~]]

OCA at 12:14, 23 September 2020

2020-09-23T12:14:53Z

← Older revision		Revision as of 12:14, 23 September 2020
Line 1:		Line 1:

	==Pim-1 kinase in complex with a 7-azaindole==		==Pim-1 kinase in complex with a 7-azaindole==
	<StructureSection load='5toe' size='340' side='right' caption='[[5toe]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5toe' size='340' side='right'caption='[[5toe]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5toe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TOE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5TOE FirstGlance]. <br>		<table><tr><td colspan='2'>[[5toe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TOE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5TOE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7GK:2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile'>7GK</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GK:2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile'>7GK</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5toe OCA], [http://pdbe.org/5toe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5toe RCSB], [http://www.ebi.ac.uk/pdbsum/5toe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5toe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5toe OCA], [http://pdbe.org/5toe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5toe RCSB], [http://www.ebi.ac.uk/pdbsum/5toe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5toe ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5toe" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5toe" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Proto-oncogene serine/threonine-protein kinase\|Proto-oncogene serine/threonine-protein kinase]]
			*[[Serine/threonine protein kinase 3D structures\|Serine/threonine protein kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Batchelor, J D]]		[[Category: Batchelor, J D]]

OCA at 06:46, 11 October 2017

2017-10-11T06:46:12Z

← Older revision		Revision as of 06:46, 11 October 2017
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 5toe is ~~ON HOLD~~ ~~until Paper~~ Publication		==Pim-1 kinase in complex with a 7-azaindole==
			<StructureSection load='5toe' size='340' side='right' caption='[[5toe]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[5toe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TOE FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7GK:2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile'>7GK</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5toe OCA], [http://pdbe.org/5toe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5toe RCSB], [http://www.ebi.ac.uk/pdbsum/5toe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5toe ProSAT]</span></td></tr>
			</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PIM1_HUMAN PIM1_HUMAN]] Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis. Mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X(L)/BCL2L1. Phosphorylation of MAP3K5, an other proapoptotic protein, by PIM1, significantly decreases MAP3K5 kinase activity and inhibits MAP3K5-mediated phosphorylation of JNK and JNK/p38MAPK subsequently reducing caspase-3 activation and cell apoptosis. Stimulates cell cycle progression at the G1-S and G2-M transitions by phosphorylation of CDC25A and CDC25C. Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of CDKN1A to the cytoplasm and enhanced CDKN1A protein stability. Promote cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression, CDKN1B, at both transcriptional and post-translational levels. Phosphorylation of CDKN1B,induces 14-3-3-proteins binding, nuclear export and proteasome-dependent degradation. May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Acts also as a regulator of homing and migration of bone marrow cells involving functional interaction with the CXCL12-CXCR4 signaling axis.<ref>PMID:1825810</ref> <ref>PMID:10664448</ref> <ref>PMID:12431783</ref> <ref>PMID:15528381</ref> <ref>PMID:16356754</ref> <ref>PMID:18593906</ref> <ref>PMID:19749799</ref>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Novel N-substituted azaindoles have been discovered as PIM1 inhibitors. X-ray structures have played a significant role in orienting the chemistry effort in the initial phase of hit confirmation. Disclosure of an unconventional binding mode for 1 and 2, as demonstrated by X-ray crystallography, is presented and was an important factor in selecting and advancing a lead series.

	~~Authors: Mclean~~, L., ~~Mechin~~, I., ~~Zhang~~, Y., ~~Wang~~, R., ~~Batchelor, J~~.D.		Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I.,Barberis C, Moorcroft N, Arendt C, Levit M, Moreno-Mazza S, Batchelor J, Mechin I, Majid T Bioorg Med Chem Lett. 2017 Oct 15;27(20):4730-4734. doi:, 10.1016/j.bmcl.2017.08.069. Epub 2017 Sep 18. PMID:28947155<ref>PMID:28947155</ref>

	~~Description: Pim~~-~~1 kinase in complex with a 7~~-~~azaindole~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	[[Category: ~~Unreleased Structures~~]]		</div>
	[[Category: Batchelor, J.D]]		<div class="pdbe-citations 5toe" style="background-color:#fffaf0;"></div>
	[[Category: ~~Zhang~~, Y]]		== References ==
			<references/>
			__TOC__
			</StructureSection>
			[[Category: Non-specific serine/threonine protein kinase]]
			[[Category: Batchelor, J D]]
			[[Category: Mclean, L]]
	[[Category: Mechin, I]]		[[Category: Mechin, I]]
	[[Category: Wang, R]]		[[Category: Wang, R]]
	[[Category: ~~Mclean~~, L]]		[[Category: Zhang, Y]]
			[[Category: Inhibitor]]
			[[Category: Kinase]]
			[[Category: Transferase-transferase inhibitor complex]]

OCA at 13:25, 27 September 2017

2017-09-27T13:25:50Z

← Older revision		Revision as of 13:25, 27 September 2017
Line 7:		Line 7:
	Description: Pim-1 kinase in complex with a 7-azaindole		Description: Pim-1 kinase in complex with a 7-azaindole
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Mechin, I]]~~
	[[Category: Batchelor, J.D]]		[[Category: Batchelor, J.D]]
	[[Category: Zhang, Y]]		[[Category: Zhang, Y]]
			[[Category: Mechin, I]]
	[[Category: Wang, R]]		[[Category: Wang, R]]
	[[Category: Mclean, L]]		[[Category: Mclean, L]]

OCA at 13:40, 9 March 2017

2017-03-09T13:40:06Z

← Older revision		Revision as of 13:40, 9 March 2017
Line 7:		Line 7:
	Description: Pim-1 kinase in complex with a 7-azaindole		Description: Pim-1 kinase in complex with a 7-azaindole
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Mechin, I]]
	[[Category: Batchelor, J.D]]		[[Category: Batchelor, J.D]]
	[[Category: Zhang, Y]]		[[Category: Zhang, Y]]
	~~[[Category: Mechin, I]]~~
	[[Category: Wang, R]]		[[Category: Wang, R]]
	[[Category: Mclean, L]]		[[Category: Mclean, L]]

OCA at 17:41, 9 December 2016

2016-12-09T17:41:49Z

← Older revision		Revision as of 17:41, 9 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 5toe is ON HOLD		The entry 5toe is ON HOLD until Paper Publication

	Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D.		Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D.

OCA: Protected "5toe" [edit=sysop:move=sysop]

2016-10-26T17:18:16Z

Protected "5toe" [edit=sysop:move=sysop]

← Older revision	Revision as of 17:18, 26 October 2016
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5toe is ON HOLD Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D. Description: Pim-1 kinase in complex with a 7-azaindole [[Cat...

2016-10-26T17:18:15Z

New page: '''Unreleased structure''' The entry 5toe is ON HOLD Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D. Description: Pim-1 kinase in complex with a 7-azaindole [[Cat...

New page

'''Unreleased structure'''

The entry 5toe is ON HOLD

Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D.

Description: Pim-1 kinase in complex with a 7-azaindole
[[Category: Unreleased Structures]]
[[Category: Batchelor, J.D]]
[[Category: Zhang, Y]]
[[Category: Mechin, I]]
[[Category: Wang, R]]
[[Category: Mclean, L]]