5wid - Revision history

OCA at 14:13, 4 October 2023

2023-10-04T14:13:51Z

← Older revision		Revision as of 14:13, 4 October 2023
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	<StructureSection load='5wid' size='340' side='right'caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='5wid' size='340' side='right'caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Metac Metac~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WID FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_acetivorans_C2A Methanosarcina acetivorans C2A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WID FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.681Å</td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MA_1799 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=188937 METAC])~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [~~http~~://pdbe.org/5wid PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wid PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [https://pdbe.org/5wid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [https://www.ebi.ac.uk/pdbsum/5wid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q8TPV5_METAC Q8TPV5_METAC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Metac~~]]		[[Category: Methanosarcina acetivorans C2A]]
	[[Category: Ferry~~, J G~~]]		[[Category: Ferry JG]]
	[[Category: Murakami~~, K S]]~~		[[Category: Murakami KS]]
	~~[[Category: Flavodoxin]]~~
	~~[[Category: Flavoprotein]]~~
	~~[[Category: Methanosarcina acetivoran~~]]

OCA at 07:20, 19 February 2020

2020-02-19T07:20:26Z

← Older revision		Revision as of 07:20, 19 February 2020
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Flavodoxins, electron transfer proteins essential for diverse metabolisms in microbes from the domain Bacteria, are extensively characterized. Remarkably, although genomic annotations of flavodoxins are widespread in microbes from the domain Archaea, none have been isolated and characterized. Herein is described the structural, biochemical, and physiological characterization of an unusual flavodoxin (FldA) from Methanosarcina acetivorans, an acetate-utilizing methane-producing microbe of the domain Archaea In contrast to all flavodoxins, FldA is homodimeric, markedly less acidic, and stabilizes an anionic semiquinone. The crystal structure reveals an flavin mononucleotide (FMN) binding site unique from all other flavodoxins that provides a rationale for stabilization of the anionic semiquinone and a remarkably low reduction potentials for both the oxidized/semiquinone (-301 mV) and semiquinone/hydroquinone couples (-464 mV). FldA is up-regulated in acetate-grown versus methanol-grown cells and shown here to substitute for ferredoxin in mediating the transfer of low potential electrons from the carbonyl of acetate to the membrane-bound electron transport chain that generates ion gradients driving ATP synthesis. FldA offers potential advantages over ferredoxin by (i) sparing iron for abundant iron-sulfur proteins essential for acetotrophic growth and (ii) resilience to oxidative damage.

			Structure and function of an unusual flavodoxin from the domain Archaea.,Prakash D, Iyer PR, Suharti S, Walters KA, Santiago-Martinez MG, Golbeck JH, Murakami KS, Ferry JG Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25917-25922. doi:, 10.1073/pnas.1908578116. Epub 2019 Dec 4. PMID:31801875<ref>PMID:31801875</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 5wid" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Flavodoxin 3D structures\|Flavodoxin 3D structures]]		*[[Flavodoxin 3D structures\|Flavodoxin 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:41, 4 December 2019

2019-12-04T09:41:37Z

← Older revision		Revision as of 09:41, 4 December 2019
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	==Structure of a flavodoxin from the domain Archaea==		==Structure of a flavodoxin from the domain Archaea==
	<StructureSection load='5wid' size='340' side='right' caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='5wid' size='340' side='right'caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Metac Metac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WID FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Metac Metac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WID FirstGlance]. <br>
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>
	</table>		</table>

			==See Also==
			*[[Flavodoxin 3D structures\|Flavodoxin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Metac]]		[[Category: Metac]]
	[[Category: Ferry, J G]]		[[Category: Ferry, J G]]

OCA at 07:36, 21 February 2019

2019-02-21T07:36:44Z

← Older revision		Revision as of 07:36, 21 February 2019
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	<StructureSection load='5wid' size='340' side='right' caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='5wid' size='340' side='right' caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WID FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Metac Metac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WID FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MA_1799 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=188937 METAC])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Metac]]
	[[Category: Ferry, J G]]		[[Category: Ferry, J G]]
	[[Category: Murakami, K S]]		[[Category: Murakami, K S]]

OCA at 21:40, 9 August 2018

2018-08-09T21:40:12Z

← Older revision		Revision as of 21:40, 9 August 2018
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 5wid is ~~ON HOLD until Paper Publication~~		==Structure of a flavodoxin from the domain Archaea==
			<StructureSection load='5wid' size='340' side='right' caption='[[5wid]], [[Resolution\|resolution]] 1.68Å' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>[[5wid]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WID FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wid OCA], [http://pdbe.org/5wid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wid RCSB], [http://www.ebi.ac.uk/pdbsum/5wid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wid ProSAT]</span></td></tr>
			</table>
			__TOC__
			</StructureSection>
			[[Category: Ferry, J G]]
			[[Category: Murakami, K S]]
			[[Category: Flavodoxin]]
			[[Category: Flavoprotein]]
			[[Category: Methanosarcina acetivoran]]

OCA at 05:33, 25 October 2017

2017-10-25T05:33:13Z

← Older revision		Revision as of 05:33, 25 October 2017
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 5wid is ON HOLD		The entry 5wid is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "5wid" [edit=sysop:move=sysop]

2017-09-27T14:51:14Z

Protected "5wid" [edit=sysop:move=sysop]

← Older revision	Revision as of 14:51, 27 September 2017
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5wid is ON HOLD Authors: Description: Category: Unreleased Structures

2017-09-27T14:51:13Z

New page: '''Unreleased structure''' The entry 5wid is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5wid is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]