5wvb - Revision history

OCA at 07:49, 22 November 2023

2023-11-22T07:49:00Z

← Older revision		Revision as of 07:49, 22 November 2023
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	<StructureSection load='5wvb' size='340' side='right'caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='5wvb' size='340' side='right'caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Asian_corn_borer Asian corn borer~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ostrinia_furnacalis Ostrinia furnacalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WVB FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NAG:N~~-~~ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.099Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14]~~ </~~span~~></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [https://pdbe.org/5wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [https://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [~~http~~://pdbe.org/5wvb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/U5LUV7_OSTFU U5LUV7_OSTFU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Asian corn borer]]~~
	~~[[Category: Chitinase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Liu, T~~]]		[[Category: Ostrinia furnacalis]]
	[[Category: ~~Yang, Q~~]]		[[Category: Liu T]]
	[[Category: ~~Zhou, Y~~]]		[[Category: Yang Q]]
	[[Category: ~~Chitin metabolism]]~~		[[Category: Zhou Y]]
	~~[[Category: Hydrolase]]~~
	~~[[Category: Ostrinia furnacali]]~~
	~~[[Category: Three-dimensional structure~~]]

OCA at 09:10, 21 October 2020

2020-10-21T09:10:04Z

← Older revision		Revision as of 09:10, 21 October 2020
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	==Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis==		==Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis==
	<StructureSection load='5wvb' size='340' side='right' caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='5wvb' size='340' side='right'caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WVB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [http://pdbe.org/5wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [http://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [http://pdbe.org/5wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [http://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
	*[[Chitinase\|Chitinase]]		*[[Chitinase 3D structures\|Chitinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	[[Category: Asian corn borer]]		[[Category: Asian corn borer]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
			[[Category: Large Structures]]
	[[Category: Liu, T]]		[[Category: Liu, T]]
	[[Category: Yang, Q]]		[[Category: Yang, Q]]

OCA at 12:24, 16 January 2019

2019-01-16T12:24:38Z

← Older revision		Revision as of 12:24, 16 January 2019
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	<StructureSection load='5wvb' size='340' side='right' caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='5wvb' size='340' side='right' caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Asian_corn_borer Asian corn borer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WVB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [http://pdbe.org/5wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [http://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [http://pdbe.org/5wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [http://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The glycoside hydrolase family 18 chitinases degrade or alter chitin. Multiple catalytic domains in a glycoside hydrolase family 18 chitinase function synergistically during chitin degradation. Here, an insect group III chitinase from the agricultural pest Ostrinia furnacalis (OfChtIII) is revealed to be an arthropod-conserved chitinase that contains two nonsynergistic GH18 domains according to its catalytic properties. Both GH18 domains are active towards single-chained chitin substrates, but are inactive towards insoluble chitin substrates. The crystal structures of each unbound GH18 domain, as well as of GH18 domains complexed with hexa-N-acetyl-chitohexaose or penta-N-acetyl-chitopentaose, suggest that the two GH18 domains possess endo-specific activities. Physiological data indicated that the developmental stage-dependent gene-expression pattern of OfChtIII was the same as that of the chitin synthase OfChsA but significantly different from that of the chitinase OfChtI, which is indispensable for cuticular chitin degradation. Additionally, immunological staining indicated that OfChtIII was co-localized with OfChsA. Thus, OfChtIII is most likely to be involved in the chitin-synthesis pathway.

			The deduced role of a chitinase containing two nonsynergistic catalytic domains.,Liu T, Zhu W, Wang J, Zhou Y, Duan Y, Qu M, Yang Q Acta Crystallogr D Struct Biol. 2018 Jan 1;74(Pt 1):30-40. doi:, 10.1107/S2059798317018289. Epub 2018 Jan 1. PMID:29372897<ref>PMID:29372897</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 5wvb" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Chitinase\|Chitinase]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Asian corn borer]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
	[[Category: Liu, T]]		[[Category: Liu, T]]

OCA at 08:29, 27 December 2017

2017-12-27T08:29:48Z

← Older revision		Revision as of 08:29, 27 December 2017
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry 5wvb is ON HOLD until Paper Publication~~		==Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis==
			<StructureSection load='5wvb' size='340' side='right' caption='[[5wvb]], [[Resolution\|resolution]] 3.10Å' scene=''>
	~~Authors: Liu, T., Zhou, Y., Yang, Q.~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[5wvb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WVB FirstGlance]. <br>
	~~Description:~~ Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5wv8\|5wv8]], [[5wv9\|5wv9]], [[5wvf\|5wvf]], [[5wvg\|5wvg]], [[5wvh\|5wvh]]</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wvb OCA], [http://pdbe.org/5wvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wvb RCSB], [http://www.ebi.ac.uk/pdbsum/5wvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wvb ProSAT]</span></td></tr>
			</table>
			__TOC__
			</StructureSection>
			[[Category: Chitinase]]
	[[Category: Liu, T]]		[[Category: Liu, T]]
	[[Category: Yang, Q]]		[[Category: Yang, Q]]
	[[Category: Zhou, Y]]		[[Category: Zhou, Y]]
			[[Category: Chitin metabolism]]
			[[Category: Hydrolase]]
			[[Category: Ostrinia furnacali]]
			[[Category: Three-dimensional structure]]

OCA at 15:08, 27 September 2017

2017-09-27T15:08:36Z

← Older revision		Revision as of 15:08, 27 September 2017
Line 7:		Line 7:
	Description: Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis		Description: Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Liu, T]]
	[[Category: Yang, Q]]		[[Category: Yang, Q]]
	~~[[Category: Liu, T]]~~
	[[Category: Zhou, Y]]		[[Category: Zhou, Y]]

OCA at 19:53, 15 March 2017

2017-03-15T19:53:45Z

← Older revision		Revision as of 19:53, 15 March 2017
Line 7:		Line 7:
	Description: Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis		Description: Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Yang, Q]]
	[[Category: Liu, T]]		[[Category: Liu, T]]
	~~[[Category: Yang, Q]]~~
	[[Category: Zhou, Y]]		[[Category: Zhou, Y]]

OCA: Protected "5wvb" [edit=sysop:move=sysop]

2017-01-04T15:55:29Z

Protected "5wvb" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:55, 4 January 2017
(No difference)

OCA: New page: '''Unreleased structure''' The entry 5wvb is ON HOLD until Paper Publication Authors: Liu, T., Zhou, Y., Yang, Q. Description: Crystal structure of a mutant insect group III chitinase ...

2017-01-04T15:55:28Z

New page: '''Unreleased structure''' The entry 5wvb is ON HOLD until Paper Publication Authors: Liu, T., Zhou, Y., Yang, Q. Description: Crystal structure of a mutant insect group III chitinase ...

New page

'''Unreleased structure'''

The entry 5wvb is ON HOLD until Paper Publication

Authors: Liu, T., Zhou, Y., Yang, Q.

Description: Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)6 (CAD1-E217L-(GlcNAc)6 ) from Ostrinia furnacalis
[[Category: Unreleased Structures]]
[[Category: Liu, T]]
[[Category: Yang, Q]]
[[Category: Zhou, Y]]