6b8a - Revision history

OCA at 13:01, 13 August 2026

2026-08-13T13:01:21Z

← Older revision		Revision as of 13:01, 13 August 2026
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	<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B8A FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZG:2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)~~acetamide~~'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZG:2-[(5-nitro-1~{H}-benzimidazol-2-yl)sulfanyl]-~{N}-(4-phenoxyphenyl)ethanamide'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [https://pdbe.org/6b8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [https://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [https://pdbe.org/6b8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [https://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>
	</table>		</table>

OCA at 14:35, 4 October 2023

2023-10-04T14:35:21Z

← Older revision		Revision as of 14:35, 4 October 2023
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	<StructureSection load='6b8a' size='340' side='right'caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='6b8a' size='340' side='right'caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6B8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B8A FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CZG:2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mvfR, AO964_20870, AOY09_01875, B0B20_09895, PAERUG_E15_London_28_01_14_10887, PAERUG_P32_London_17_VIM_2_10_11_05492, PAMH19_4335 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZG:2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [~~http~~://pdbe.org/6b8a PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [https://pdbe.org/6b8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [https://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/MVFR_PSEAE MVFR_PSEAE] Transcription regulator that plays a critical role in virulence by positively regulating the expression of multiple quorum sensing (QS)-regulated virulence factors, genes involved in protein secretion, translation, response to oxidative stress and the phnAB operon (PubMed:11724939, PubMed:27678057, PubMed:17083468). At the stationary phase, negatively autoregulates its function through cleavage and translocation to the extracellular space (PubMed:11724939).<ref>PMID:11724939</ref> <ref>PMID:17083468</ref> <ref>PMID:27678057</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 6b8a" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 6b8a" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Transcriptional activator 3D structures\|Transcriptional activator 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Blaesse, M]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Kitao, T]]		[[Category: Blaesse M]]
	[[Category: Maskos, K]]		[[Category: Kitao T]]
	[[Category: Rahme~~, L G~~]]		[[Category: Maskos K]]
	[[Category: Steinbacher, S]]		[[Category: Rahme LG]]
	~~[[Category: Mvfr transcriptional regulator]]~~		[[Category: Steinbacher S]]
	~~[[Category: Pqsr]]~~
	~~[[Category: Transcription~~]]

OCA at 17:44, 11 December 2019

2019-12-11T17:44:10Z

← Older revision		Revision as of 17:44, 11 December 2019
Line 1:		Line 1:

	==Crystal structure of MvfR ligand binding domain in complex with M64==		==Crystal structure of MvfR ligand binding domain in complex with M64==
	<StructureSection load='6b8a' size='340' side='right' caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='6b8a' size='340' side='right'caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B8A FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Blaesse, M]]		[[Category: Blaesse, M]]
	[[Category: Kitao, T]]		[[Category: Kitao, T]]

OCA at 07:04, 15 February 2018

2018-02-15T07:04:10Z

← Older revision		Revision as of 07:04, 15 February 2018
Line 3:		Line 3:
	<StructureSection load='6b8a' size='340' side='right' caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='6b8a' size='340' side='right' caption='[[6b8a]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[6b8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B8A FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CZG:2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CZG:2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide'>CZG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mvfR, AO964_20870, AOY09_01875, B0B20_09895, PAERUG_E15_London_28_01_14_10887, PAERUG_P32_London_17_VIM_2_10_11_05492, PAMH19_4335 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [http://pdbe.org/6b8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [http://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8a OCA], [http://pdbe.org/6b8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b8a RCSB], [http://www.ebi.ac.uk/pdbsum/6b8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8a ProSAT]</span></td></tr>
	</table>		</table>

OCA at 05:57, 31 January 2018

2018-01-31T05:57:37Z

@@ Line 1: / Line 1: @@
-The entry 6b8a is ON HOLD
+==Crystal structure of MvfR ligand binding domain in complex with M64==
-Authors:
+Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator.,Kitao T, Lepine F, Babloudi S, Walte F, Steinbacher S, Maskos K, Blaesse M, Negri M, Pucci M, Zahler B, Felici A, Rahme LG MBio. 2018 Jan 16;9(1). pii: mBio.02158-17. doi: 10.1128/mBio.02158-17. PMID:29339431<ref>PMID:29339431</ref>
-Description:
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>

OCA: Protected "6b8a" [edit=sysop:move=sysop]

2017-10-11T05:40:17Z

Protected "6b8a" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:40, 11 October 2017
(No difference)

OCA: New page: '''Unreleased structure''' The entry 6b8a is ON HOLD Authors: Description: Category: Unreleased Structures

2017-10-11T05:40:15Z

New page: '''Unreleased structure''' The entry 6b8a is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6b8a is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]