6ffd - Revision history

OCA at 12:27, 9 May 2024

2024-05-09T12:27:45Z

← Older revision		Revision as of 12:27, 9 May 2024
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	==Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone==		==Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone==
	<StructureSection load='6ffd' size='340' side='right' caption='[[6ffd]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='6ffd' size='340' side='right'caption='[[6ffd]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ffd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6FFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ffd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FFD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7T:1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone'>D7T</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.83Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ffd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffd OCA], [~~http~~://pdbe.org/6ffd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ffd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ffd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffd ProSAT]</span></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D7T:1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone'>D7T</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ffd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffd OCA], [https://pdbe.org/6ffd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ffd RCSB], [https://www.ebi.ac.uk/pdbsum/6ffd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffd ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>		[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).		[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

			==See Also==
			*[[Bromodomain-containing protein 3D structures\|Bromodomain-containing protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Chung, C~~]]		[[Category: Homo sapiens]]
	[[Category: ~~Antagonist~~]]		[[Category: Large Structures]]
	[[Category: ~~Brd4]]~~		[[Category: Chung C]]
	~~[[Category: Bromodomain]]~~
	~~[[Category: Bromodomain containing protein 4]]~~
	~~[[Category: Epigenetic reader]]~~
	~~[[Category: Histone]]~~
	~~[[Category: Inhibitor]]~~
	~~[[Category: Transcription~~]]

OCA at 08:21, 30 January 2019

2019-01-30T08:21:27Z

@@ Line 1: / Line 1: @@
-The entry 6ffd is ON HOLD  until Paper Publication
+==Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone==
+<StructureSection load='6ffd' size='340' side='right' caption='[[6ffd]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ffd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFD FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7T:1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone'>D7T</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffd OCA], [http://pdbe.org/6ffd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffd RCSB], [http://www.ebi.ac.uk/pdbsum/6ffd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffd ProSAT]</span></td></tr>

OCA: Protected "6ffd" [edit=sysop:move=sysop]

2018-01-17T05:52:00Z

Protected "6ffd" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:52, 17 January 2018
(No difference)

OCA: New page: '''Unreleased structure''' The entry 6ffd is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

2018-01-17T05:51:58Z

New page: '''Unreleased structure''' The entry 6ffd is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ffd is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]