6ool - Revision history

OCA at 05:32, 21 November 2024

2024-11-21T05:32:34Z

← Older revision		Revision as of 05:32, 21 November 2024
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	<StructureSection load='6ool' size='340' side='right'caption='[[6ool]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='6ool' size='340' side='right'caption='[[6ool]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>~~[[6ool]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OOL FirstGlance]. <br>		<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OOL FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ool OCA], [https://pdbe.org/6ool PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ool RCSB], [https://www.ebi.ac.uk/pdbsum/6ool PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ool ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ool OCA], [https://pdbe.org/6ool PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ool RCSB], [https://www.ebi.ac.uk/pdbsum/6ool PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ool ProSAT]</span></td></tr>
	</table>		</table>
	~~== Function ==~~
	[https://www.uniprot.org/uniprot/UNC5B_MOUSE UNC5B_MOUSE] Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity).<ref>PMID:15729359</ref>

	==See Also==		==See Also==
	*[[Netrin receptor\|Netrin receptor]]		*[[Netrin receptor\|Netrin receptor]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Mus musculus]]~~
	[[Category: Loewen PC]]		[[Category: Loewen PC]]
	[[Category: McDougall MD]]		[[Category: McDougall MD]]

OCA at 07:14, 11 October 2023

2023-10-11T07:14:11Z

← Older revision		Revision as of 07:14, 11 October 2023
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	==Structural elucidation of the Ectodomain of mouse UNC5H2==		==Structural elucidation of the Ectodomain of mouse UNC5H2==
	<StructureSection load='6ool' size='340' side='right'caption='[[6ool]]' scene=''>		<StructureSection load='6ool' size='340' side='right'caption='[[6ool]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OOL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6OOL FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ool]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OOL FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ool OCA], [~~http~~://pdbe.org/6ool PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ool RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ool PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ool ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ool OCA], [https://pdbe.org/6ool PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ool RCSB], [https://www.ebi.ac.uk/pdbsum/6ool PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ool ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/UNC5B_MOUSE UNC5B_MOUSE] Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity).<ref>PMID:15729359</ref>

			==See Also==
			*[[Netrin receptor\|Netrin receptor]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
			[[Category: Mus musculus]]
	[[Category: Loewen PC]]		[[Category: Loewen PC]]
	[[Category: McDougall MD]]		[[Category: McDougall MD]]

OCA at 06:41, 29 April 2020

2020-04-29T06:41:43Z

← Older revision		Revision as of 06:41, 29 April 2020
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 6ool is ~~ON HOLD until Paper Publication~~		==Structural elucidation of the Ectodomain of mouse UNC5H2==
			<StructureSection load='6ool' size='340' side='right'caption='[[6ool]]' scene=''>
	~~Authors~~: ~~Stetefeld~~, J., ~~McDougall~~, M.D., ~~Loewen, P~~.C., ~~Moya, A~~.~~, Meier, M~~.		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OOL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6OOL FirstGlance]. <br>
	~~Description: Structural elucidation of the Ectodomain of mouse UNC5H2~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ool OCA], [http://pdbe.org/6ool PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ool RCSB], [http://www.ebi.ac.uk/pdbsum/6ool PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ool ProSAT]</span></td></tr>
	[[Category: ~~Unreleased~~ Structures]]		</table>
	[[Category: ~~Moya, A~~]]		__TOC__
	[[Category: ~~Stetefeld, J~~]]		</StructureSection>
	[[Category: Meier, M]]		[[Category: Large Structures]]
	[[Category: ~~Loewen, P.C~~]]		[[Category: Loewen PC]]
	[[Category: ~~Mcdougall, M.D~~]]		[[Category: McDougall MD]]
			[[Category: Meier M]]
			[[Category: Moya A]]
			[[Category: Stetefeld J]]

OCA: Protected "6ool" [edit=sysop:move=sysop]

2019-05-01T07:14:09Z

Protected "6ool" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:14, 1 May 2019
(No difference)

OCA: New page: '''Unreleased structure''' The entry 6ool is ON HOLD until Paper Publication Authors: Stetefeld, J., McDougall, M.D., Loewen, P.C., Moya, A., Meier, M. Description: Structural elucidat...

2019-05-01T07:14:08Z

New page: '''Unreleased structure''' The entry 6ool is ON HOLD until Paper Publication Authors: Stetefeld, J., McDougall, M.D., Loewen, P.C., Moya, A., Meier, M. Description: Structural elucidat...

New page

'''Unreleased structure'''

The entry 6ool is ON HOLD until Paper Publication

Authors: Stetefeld, J., McDougall, M.D., Loewen, P.C., Moya, A., Meier, M.

Description: Structural elucidation of the Ectodomain of mouse UNC5H2
[[Category: Unreleased Structures]]
[[Category: Moya, A]]
[[Category: Stetefeld, J]]
[[Category: Meier, M]]
[[Category: Loewen, P.C]]
[[Category: Mcdougall, M.D]]