6ppd - Revision history

OCA at 13:00, 6 November 2024

2024-11-06T13:00:08Z

← Older revision		Revision as of 13:00, 6 November 2024
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	<SX load='6ppd' size='340' side='right' viewer='molstar' caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>		<SX load='6ppd' size='340' side='right' viewer='molstar' caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human_herpesvirus_8~~ Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6PPD FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PPD FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">[[~~6ppb~~\|~~6ppb~~]]</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.7Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ppd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppd OCA], [~~http~~://pdbe.org/6ppd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ppd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ppd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ppd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppd OCA], [https://pdbe.org/6ppd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ppd RCSB], [https://www.ebi.ac.uk/pdbsum/6ppd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/C7E5A9_HHV8 C7E5A9_HHV8]] Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.[HAMAP-Rule:MF_04019] [[http://www.uniprot.org/uniprot/~~Q76RF4_HHV8 Q76RF4_HHV8]~~] Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument. Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.[HAMAP-Rule:MF_04022] [[http://www.uniprot.org/uniprot/Q76RF6_HHV8 Q76RF6_HHV8]] Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.[HAMAP-Rule:MF_04018] [[http://www.uniprot.org/uniprot/D0UZN7_HHV8 D0UZN7_HHV8]] Self-assembles to form an icosahedral capsid with a T=16 symmetry, about 200 nm in diameter, and consisting of 150 hexons and 12 pentons (total of 162 capsomers). Hexons form the edges and faces of the capsid and are each composed of six MCP molecules. In contrast, one penton is found at each of the 12 vertices. Eleven of the pentons are MCP pentamers, while the last vertex is occupied by the portal complex. The capsid is surrounded by a layer of proteinaceous material designated the tegument which, in turn, is enclosed in an envelope of host cell-derived lipids containing virus-encoded glycoproteins.[HAMAP-Rule:MF_04016]		[https://www.uniprot.org/uniprot/SCP_HHV8P SCP_HHV8P] Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument. Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.[HAMAP-Rule:MF_04022]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</SX>		</SX>
	[[Category: Human herpesvirus 8]]		[[Category: Human herpesvirus 8 strain GK18]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bi~~, G Q~~]]		[[Category: Bi GQ]]
	[[Category: Dai, X]]		[[Category: Dai X]]
	[[Category: Gong, D]]		[[Category: Gong D]]
	[[Category: Jih, J]]		[[Category: Jih J]]
	[[Category: Liu~~, Y T~~]]		[[Category: Liu YT]]
	[[Category: Sun, R]]		[[Category: Sun R]]
	[[Category: Zhou~~, Z H]]~~		[[Category: Zhou ZH]]
	~~[[Category: Capsid]]~~
	~~[[Category: Complex]]~~
	~~[[Category: Tegument]]~~
	~~[[Category: Vertex]]~~
	~~[[Category: Viral protein]]~~
	~~[[Category: Virus~~]]

OCA at 04:31, 11 April 2020

2020-04-11T04:31:42Z

← Older revision		Revision as of 04:31, 11 April 2020
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	<SX load='6ppd' size='340' side='right' viewer='molstar' caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>		<SX load='6ppd' size='340' side='right' viewer='molstar' caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6PPD FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6PPD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6ppb\|6ppb]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[6ppb\|6ppb]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=6ppd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppd OCA], [http://pdbe.org/6ppd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ppd RCSB], [http://www.ebi.ac.uk/pdbsum/6ppd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ppd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppd OCA], [http://pdbe.org/6ppd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ppd RCSB], [http://www.ebi.ac.uk/pdbsum/6ppd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:25, 6 March 2020

2020-03-06T23:25:15Z

← Older revision		Revision as of 23:25, 6 March 2020
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	==Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-absent structure==		==Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-absent structure==
	<~~StructureSection~~ load='6ppd' size='340' side='right'caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>		<SX load='6ppd' size='340' side='right' viewer='molstar' caption='[[6ppd]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PPD FirstGlance]. <br>		<table><tr><td colspan='2'>[[6ppd]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PPD FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
	</~~StructureSection~~>		</SX>
	[[Category: Human herpesvirus 8]]		[[Category: Human herpesvirus 8]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 09:19, 27 November 2019

2019-11-27T09:19:17Z

@@ Line 1: / Line 1: @@
-The entry 6ppd is ON HOLD  until Paper Publication
+==Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-absent structure==
-Authors:
+DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV.,Gong D, Dai X, Jih J, Liu YT, Bi GQ, Sun R, Zhou ZH Cell. 2019 Sep 5;178(6):1329-1343.e12. doi: 10.1016/j.cell.2019.07.035. Epub 2019, Aug 22. PMID:31447177<ref>PMID:31447177</ref>
-Description:
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>

OCA at 04:42, 31 July 2019

2019-07-31T04:42:24Z

← Older revision		Revision as of 04:42, 31 July 2019
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 6ppd is ON HOLD		The entry 6ppd is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "6ppd" [edit=sysop:move=sysop]

2019-07-17T09:03:44Z

Protected "6ppd" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:03, 17 July 2019
(No difference)

OCA: New page: '''Unreleased structure''' The entry 6ppd is ON HOLD Authors: Description: Category: Unreleased Structures

2019-07-17T09:03:42Z

New page: '''Unreleased structure''' The entry 6ppd is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 6ppd is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]