6vb1 - Revision history

OCA at 10:35, 23 October 2024

2024-10-23T10:35:03Z

← Older revision		Revision as of 10:35, 23 October 2024
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [https://pdbe.org/6vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [https://pdbe.org/6vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>
	</table>		</table>
			== Disease ==
			[https://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[https://omim.org/entry/241600 241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref> Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref> <ref>PMID:1336137</ref> <ref>PMID:7554280</ref> <ref>PMID:4586824</ref> <ref>PMID:8084451</ref> <ref>PMID:12119416</ref> <ref>PMID:12796775</ref> <ref>PMID:16901902</ref> <ref>PMID:16491088</ref> <ref>PMID:17646174</ref> <ref>PMID:18835253</ref> <ref>PMID:18395224</ref> <ref>PMID:19284997</ref>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/~~F4NBQ8_HUMAN F4NBQ8_HUMAN~~]		[https://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.

	==See Also==		==See Also==
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	*[[MHC 3D structures\|MHC 3D structures]]		*[[MHC 3D structures\|MHC 3D structures]]
	*[[MHC I 3D structures\|MHC I 3D structures]]		*[[MHC I 3D structures\|MHC I 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:07, 11 October 2023

2023-10-11T08:07:58Z

← Older revision		Revision as of 08:07, 11 October 2023
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	====		==HLA-B*15:02 complexed with a synthetic peptide==
	<StructureSection load='6vb1' size='340' side='right'caption='[[6vb1]]' scene=''>		<StructureSection load='6vb1' size='340' side='right'caption='[[6vb1]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>		<table><tr><td colspan='2'>[[6vb1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VB1 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [https://pdbe.org/6vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [https://pdbe.org/6vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/F4NBQ8_HUMAN F4NBQ8_HUMAN]

			==See Also==
			*[[Beta-2 microglobulin 3D structures\|Beta-2 microglobulin 3D structures]]
			*[[MHC 3D structures\|MHC 3D structures]]
			*[[MHC I 3D structures\|MHC I 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Z-disk~~]]		[[Category: Synthetic construct]]
			[[Category: Andring J]]
			[[Category: Li D]]
			[[Category: McKenna R]]
			[[Category: Ostrov DA]]
			[[Category: Schutte RJ]]

OCA at 07:11, 16 March 2022

2022-03-16T07:11:28Z

← Older revision		Revision as of 07:11, 16 March 2022
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	<StructureSection load='6vb1' size='340' side='right'caption='[[6vb1]]' scene=''>		<StructureSection load='6vb1' size='340' side='right'caption='[[6vb1]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>		<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [~~http~~://pdbe.org/6vb1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [https://pdbe.org/6vb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [https://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 06:53, 25 November 2020

2020-11-25T06:53:58Z

← Older revision		Revision as of 06:53, 25 November 2020
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	~~'''Unreleased structure'''~~

	~~The entry~~ 6vb1 ~~is ON HOLD until Paper Publication~~		====
			<StructureSection load='6vb1' size='340' side='right'caption='[[6vb1]]' scene=''>
	~~Authors~~: ~~Schutte, R~~.J.~~, Li, D~~.~~, Andring, J~~.~~, McKenna, R~~.~~, Ostrov, D~~.A.		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
	~~Description~~: ~~HLA-B*15~~:~~02 complexed with a synthetic peptide~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6vb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vb1 OCA], [http://pdbe.org/6vb1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vb1 RCSB], [http://www.ebi.ac.uk/pdbsum/6vb1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vb1 ProSAT]</span></td></tr>
	[[~~Category~~: ~~Unreleased Structures~~]]		</table>
	[~~[Category~~: Li, ~~D]]~~		__TOC__
	[~~[Category~~: ~~Mckenna~~, ~~R]]~~		</StructureSection>
	[~~[Category~~: ~~Schutte, R~~.J]]		[[Category: Large Structures]]
	[[Category: ~~Ostrov, D.A~~]]		[[Category: Z-disk]]
	[[Category: ~~Andring, J~~]]

OCA at 14:16, 22 January 2020

2020-01-22T14:16:25Z

← Older revision		Revision as of 14:16, 22 January 2020
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 6vb1 is ON HOLD		The entry 6vb1 is ON HOLD until Paper Publication

	Authors: Schutte, R.J., Li, D., Andring, J., McKenna, R., Ostrov, D.A.		Authors: Schutte, R.J., Li, D., Andring, J., McKenna, R., Ostrov, D.A.

OCA: Protected "6vb1" [edit=sysop:move=sysop]

2019-12-25T07:37:30Z

Protected "6vb1" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:37, 25 December 2019
(No difference)

OCA: New page: '''Unreleased structure''' The entry 6vb1 is ON HOLD Authors: Schutte, R.J., Li, D., Andring, J., McKenna, R., Ostrov, D.A. Description: HLA-B*15:02 complexed with a synthetic peptide ...

2019-12-25T07:37:29Z

New page: '''Unreleased structure''' The entry 6vb1 is ON HOLD Authors: Schutte, R.J., Li, D., Andring, J., McKenna, R., Ostrov, D.A. Description: HLA-B*15:02 complexed with a synthetic peptide ...

New page

'''Unreleased structure'''

The entry 6vb1 is ON HOLD

Authors: Schutte, R.J., Li, D., Andring, J., McKenna, R., Ostrov, D.A.

Description: HLA-B*15:02 complexed with a synthetic peptide
[[Category: Unreleased Structures]]
[[Category: Li, D]]
[[Category: Mckenna, R]]
[[Category: Schutte, R.J]]
[[Category: Ostrov, D.A]]
[[Category: Andring, J]]