7a8a - Revision history

OCA at 08:33, 17 October 2024

2024-10-17T08:33:47Z

← Older revision		Revision as of 08:33, 17 October 2024
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	<StructureSection load='7a8a' size='340' side='right'caption='[[7a8a]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='7a8a' size='340' side='right'caption='[[7a8a]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>~~[[7a8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeqvi Aeqvi].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8A FirstGlance]. <br>		<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8A FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CRO:{2~~-[~~(1R,2R)-1-AMINO-2-HYDROXYPROPYL~~]~~-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-~~1~~-YL}ACETIC+ACID'>CRO</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.93Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;'>~~[~~[4xow\|4xow]~~], ~~[[4xov\|4xov]]</div></td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</~~b></td><td class="sblockDat"~~>~~gfp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8a OCA], [https://pdbe.org/7a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8a RCSB], [https://www.ebi.ac.uk/pdbsum/7a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8a ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8a OCA], [https://pdbe.org/7a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8a RCSB], [https://www.ebi.ac.uk/pdbsum/7a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8a ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 7a8a" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 7a8a" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Green Fluorescent Protein 3D structures\|Green Fluorescent Protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Aeqvi]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Dedecker, P]]~~		[[Category: De Zitter E]]
	~~[[Category: Meervelt, L Van]]~~		[[Category: Dedecker P]]
	~~[[Category:~~ Zitter, E De]]		[[Category: Van Meervelt L]]
	[[Category: ~~Fluorescent protein~~]]
	[[Category: ~~Reversible photoswitchable fluorescent protein~~]]

OCA at 09:05, 5 May 2021

2021-05-05T09:05:47Z

← Older revision		Revision as of 09:05, 5 May 2021
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	==rsGreen0.7-K206A-F145Q partially in the green-off state==		==rsGreen0.7-K206A-F145Q partially in the green-off state==
	<StructureSection load='7a8a' size='340' side='right'caption='[[7a8a]]' scene=''>		<StructureSection load='7a8a' size='340' side='right'caption='[[7a8a]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8A FirstGlance]. <br>		<table><tr><td colspan='2'>[[7a8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeqvi Aeqvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8A FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8a OCA], [https://pdbe.org/7a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8a RCSB], [https://www.ebi.ac.uk/pdbsum/7a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8a ProSAT]</span></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4xow\|4xow]], [[4xov\|4xov]]</div></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gfp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8a OCA], [https://pdbe.org/7a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8a RCSB], [https://www.ebi.ac.uk/pdbsum/7a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8a ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Anisotropic environments can drastically alter the spectroscopy and photochemistry of molecules, leading to complex structure-function relationships. We examined this using fluorescent proteins as easy-to-modify model systems. Starting from a single scaffold, we have developed a range of 27 photochromic fluorescent proteins that cover a broad range of spectroscopic properties, including the determination of 43 crystal structures. Correlation and principal component analysis confirmed the complex relationship between structure and spectroscopy, but also allowed us to identify consistent trends and to relate these to the spatial organization. We find that changes in spectroscopic properties can come about through multiple underlying mechanisms, of which polarity, hydrogen bonding and presence of water molecules are key modulators. We anticipate that our findings and rich structure/spectroscopy dataset can open opportunities for the development and evaluation of new and existing protein engineering methods.

			Structure-Function Dataset Reveals Environment Effects within a Fluorescent Protein Model System.,De Zitter E, Hugelier S, Duwe S, Vandenberg W, Tebo AG, Van Meervelt L, Dedecker P Angew Chem Int Ed Engl. 2021 Feb 4. doi: 10.1002/anie.202015201. PMID:33543524<ref>PMID:33543524</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7a8a" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Aeqvi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: De Zitter E]]		[[Category: Dedecker, P]]
	[[Category: ~~Dedecker P~~]]		[[Category: Meervelt, L Van]]
	[[Category: ~~Van Meervelt L~~]]		[[Category: Zitter, E De]]
			[[Category: Fluorescent protein]]
			[[Category: Reversible photoswitchable fluorescent protein]]

OCA at 09:59, 17 February 2021

2021-02-17T09:59:56Z

← Older revision		Revision as of 09:59, 17 February 2021
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7a8a is ~~ON HOLD~~		==rsGreen0.7-K206A-F145Q partially in the green-off state==
			<StructureSection load='7a8a' size='340' side='right'caption='[[7a8a]]' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8A FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8a OCA], [https://pdbe.org/7a8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8a RCSB], [https://www.ebi.ac.uk/pdbsum/7a8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8a ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: De Zitter E]]
			[[Category: Dedecker P]]
			[[Category: Van Meervelt L]]

OCA: Protected "7a8a" [edit=sysop:move=sysop]

2020-09-09T07:14:50Z

Protected "7a8a" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:14, 9 September 2020
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7a8a is ON HOLD Authors: Description: Category: Unreleased Structures

2020-09-09T07:14:48Z

New page: '''Unreleased structure''' The entry 7a8a is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7a8a is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]