7bwe - Revision history

OCA at 11:11, 14 June 2023

2023-06-14T11:11:34Z

← Older revision		Revision as of 11:11, 14 June 2023
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	==Consensus Chitin binding domain==		==Consensus Chitin binding domain==
	<StructureSection load='7bwe' size='340' side='right'caption='[[7bwe~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>		<StructureSection load='7bwe' size='340' side='right'caption='[[7bwe]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7bwe]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[7bwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dosidicus_gigas Dosidicus gigas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BWE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bwe OCA], [https://pdbe.org/7bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bwe RCSB], [https://www.ebi.ac.uk/pdbsum/7bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bwe ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bwe OCA], [https://pdbe.org/7bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bwe RCSB], [https://www.ebi.ac.uk/pdbsum/7bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bwe ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/A0A0G2UHG5_DOSGI A0A0G2UHG5_DOSGI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Dosidicus gigas]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Miserez, A]]		[[Category: Miserez A]]
	[[Category: Mohanram, H]]		[[Category: Mohanram H]]
	~~[[Category: Chitin binding protein]]~~
	~~[[Category: Chitopentaose]]~~
	~~[[Category: Std-nmr]]~~
	~~[[Category: Sugar binding protein~~]]

OCA at 08:32, 21 April 2021

2021-04-21T08:32:08Z

← Older revision		Revision as of 08:32, 21 April 2021
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	==Consensus Chitin binding domain==		==Consensus Chitin binding domain==
	<StructureSection load='7bwe' size='340' side='right'caption='[[7bwe]]' scene=''>		<StructureSection load='7bwe' size='340' side='right'caption='[[7bwe]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[7bwe]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BWE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bwe OCA], [https://pdbe.org/7bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bwe RCSB], [https://www.ebi.ac.uk/pdbsum/7bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bwe ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bwe OCA], [https://pdbe.org/7bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bwe RCSB], [https://www.ebi.ac.uk/pdbsum/7bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bwe ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Chitin-binding proteins (CBPs) are a versatile group of proteins found in almost every organism on earth. CBPs are involved in enzymatic carbohydrate degradation and also serve as templating scaffolds in the exoskeleton of crustaceans and insects. One specific chitin-binding motif found across a wide range of arthropods' exoskeletons is the "extended Rebers and Riddiford" consensus (R&R), whose mechanism of chitin binding remains unclear. Here, we report the 3D structure and molecular level interactions of a chitin-binding domain (CBD-gamma) located in a CBP from the beak of the jumbo squid Dosidicus gigas. This CBP is one of four chitin-binding proteins identified in the beak mouthpart of D. gigas and is believed to interact with chitin to form a scaffold network that is infiltrated with a second set of structural proteins during beak maturation. We used solution state NMR spectroscopy to elucidate the molecular interactions between CBD-gamma and the soluble chitin derivative pentaacetyl-chitopentaose (PCP), and find that folding of CBD-gamma is triggered upon its interaction with PCP. To our knowledge, this is the first experimental 3D structure of a CBP containing the R&R consensus motif, which can be used as a template to understand in more details the role of the R&R motif found in a wide range of CBP-chitin complexes. The present structure also provides molecular information for biomimetic synthesis of graded biomaterials using aqueous-based chemistry and biopolymers.

			Structure of a consensus chitin-binding domain revealed by solution NMR.,Heymann D, Mohanram H, Kumar A, Verma CS, Lescar J, Miserez A J Struct Biol. 2021 Mar 18;213(2):107725. doi: 10.1016/j.jsb.2021.107725. PMID:33744410<ref>PMID:33744410</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7bwe" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Miserez A]]		[[Category: Miserez, A]]
	[[Category: Mohanram H]]		[[Category: Mohanram, H]]
			[[Category: Chitin binding protein]]
			[[Category: Chitopentaose]]
			[[Category: Std-nmr]]
			[[Category: Sugar binding protein]]

OCA at 06:46, 14 April 2021

2021-04-14T06:46:10Z

← Older revision		Revision as of 06:46, 14 April 2021
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7bwe is ~~ON HOLD until Paper Publication~~		==Consensus Chitin binding domain==
			<StructureSection load='7bwe' size='340' side='right'caption='[[7bwe]]' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BWE FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bwe OCA], [https://pdbe.org/7bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bwe RCSB], [https://www.ebi.ac.uk/pdbsum/7bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bwe ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Miserez A]]
			[[Category: Mohanram H]]

OCA at 13:11, 3 March 2021

2021-03-03T13:11:18Z

← Older revision		Revision as of 13:11, 3 March 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7bwe is ON HOLD		The entry 7bwe is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7bwe" [edit=sysop:move=sysop]

2020-04-22T04:38:24Z

Protected "7bwe" [edit=sysop:move=sysop]

← Older revision	Revision as of 04:38, 22 April 2020
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7bwe is ON HOLD Authors: Description: Category: Unreleased Structures

2020-04-22T04:38:23Z

New page: '''Unreleased structure''' The entry 7bwe is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7bwe is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]