7dds - Revision history

OCA at 14:07, 13 August 2026

2026-08-13T14:07:06Z

← Older revision		Revision as of 14:07, 13 August 2026
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	<StructureSection load='7dds' size='340' side='right'caption='[[7dds]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='7dds' size='340' side='right'caption='[[7dds]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>~~[[7dds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DDS FirstGlance]. <br>		<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DDS FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Synthetic construct]]~~
	[[Category: Imamura H]]		[[Category: Imamura H]]
	[[Category: Isogai Y]]		[[Category: Isogai Y]]

OCA at 16:31, 29 November 2023

2023-11-29T16:31:12Z

← Older revision		Revision as of 16:31, 29 November 2023
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	==Ancestral myoglobin aMbSp of Puijila Darwini relative==		==Ancestral myoglobin aMbSp of Puijila Darwini relative==
	<StructureSection load='7dds' size='340' side='right'caption='[[7dds]]' scene=''>		<StructureSection load='7dds' size='340' side='right'caption='[[7dds]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DDS FirstGlance]. <br>		<table><tr><td colspan='2'>[[7dds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DDS FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dds OCA], [https://pdbe.org/7dds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dds RCSB], [https://www.ebi.ac.uk/pdbsum/7dds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dds ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dds OCA], [https://pdbe.org/7dds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dds RCSB], [https://www.ebi.ac.uk/pdbsum/7dds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dds ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Myoglobin (Mb) is highly concentrated in the myocytes of diving mammals such as whales and seals, in comparison with land animals, and its molecular evolution has played a crucial role in their deep-sea adaptation. We previously resurrected ancestral whale Mbs and demonstrated the evolutional strategies for higher solubility under macromolecular crowding conditions. Pinnipeds, such as seals and sea lions, are also expert diving mammals with Mb-rich muscles. In the present study, we resurrected ancestral pinniped Mbs and investigated their biochemical and structural properties. Comparisons between pinniped and whale Mbs revealed the common and distinctive strategies for the deep-sea adaptation. The overall evolution processes, gaining precipitant tolerance and improving thermodynamic stability, were commonly observed. However, the strategies for improving the folding stability differed, and the pinniped Mbs exploited the shielding of hydrophobic surfaces more effectively than the whale Mbs.

			Common and unique strategies of myoglobin evolution for deep-sea adaptation of diving mammals.,Isogai Y, Imamura H, Nakae S, Sumi T, Takahashi KI, Shirai T iScience. 2021 Jul 30;24(8):102920. doi: 10.1016/j.isci.2021.102920. eCollection , 2021 Aug 20. PMID:34430810<ref>PMID:34430810</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7dds" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Myoglobin 3D structures\|Myoglobin 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
			[[Category: Synthetic construct]]
	[[Category: Imamura H]]		[[Category: Imamura H]]
	[[Category: Isogai Y]]		[[Category: Isogai Y]]

OCA at 08:56, 8 September 2021

2021-09-08T08:56:16Z

← Older revision		Revision as of 08:56, 8 September 2021
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7dds is ~~ON HOLD until Paper Publication~~		==Ancestral myoglobin aMbSp of Puijila Darwini relative==
			<StructureSection load='7dds' size='340' side='right'caption='[[7dds]]' scene=''>
	~~Authors~~: ~~Isogai~~, Y., ~~Imamura~~, H., ~~Nakae, S~~.~~, Sumi, T~~., ~~Takahashi, K~~.~~, Shirai, T~~.		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DDS FirstGlance]. <br>
	~~Description: Ancestral myoglobin aMbSp of Puijila Darwini relative~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dds OCA], [https://pdbe.org/7dds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dds RCSB], [https://www.ebi.ac.uk/pdbsum/7dds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dds ProSAT]</span></td></tr>
	[[Category: ~~Unreleased~~ Structures]]		</table>
	[[Category: ~~Sumi, T~~]]		__TOC__
	[[Category: Isogai, Y]]		</StructureSection>
	[[Category: ~~Takahashi, K~~]]		[[Category: Large Structures]]
	[[Category: Shirai, T]]		[[Category: Imamura H]]
	[[Category: ~~Nakae, S~~]]		[[Category: Isogai Y]]
	[[Category: ~~Imamura, H~~]]		[[Category: Nakae S]]
			[[Category: Shirai T]]
			[[Category: Sumi T]]
			[[Category: Takahashi K]]

OCA at 13:20, 2 June 2021

2021-06-02T13:20:48Z

← Older revision		Revision as of 13:20, 2 June 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7dds is ON HOLD		The entry 7dds is ON HOLD until Paper Publication

	Authors: Isogai, Y., Imamura, H., Nakae, S., Sumi, T., Takahashi, K., Shirai, T.		Authors: Isogai, Y., Imamura, H., Nakae, S., Sumi, T., Takahashi, K., Shirai, T.
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	Description: Ancestral myoglobin aMbSp of Puijila Darwini relative		Description: Ancestral myoglobin aMbSp of Puijila Darwini relative
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Sumi, T]]
			[[Category: Isogai, Y]]
			[[Category: Takahashi, K]]
	[[Category: Shirai, T]]		[[Category: Shirai, T]]
	[[Category: Nakae, S]]		[[Category: Nakae, S]]
	~~[[Category: Sumi, T]]~~
	~~[[Category: Takahashi, K]]~~
	~~[[Category: Isogai, Y]]~~
	[[Category: Imamura, H]]		[[Category: Imamura, H]]

OCA: Protected "7dds" [edit=sysop:move=sysop]

2020-11-04T05:32:49Z

Protected "7dds" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:32, 4 November 2020
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7dds is ON HOLD Authors: Isogai, Y., Imamura, H., Nakae, S., Sumi, T., Takahashi, K., Shirai, T. Description: Ancestral myoglobin aMbSp of Puijila ...

2020-11-04T05:32:48Z

New page: '''Unreleased structure''' The entry 7dds is ON HOLD Authors: Isogai, Y., Imamura, H., Nakae, S., Sumi, T., Takahashi, K., Shirai, T. Description: Ancestral myoglobin aMbSp of Puijila ...

New page

'''Unreleased structure'''

The entry 7dds is ON HOLD

Authors: Isogai, Y., Imamura, H., Nakae, S., Sumi, T., Takahashi, K., Shirai, T.

Description: Ancestral myoglobin aMbSp of Puijila Darwini relative
[[Category: Unreleased Structures]]
[[Category: Shirai, T]]
[[Category: Nakae, S]]
[[Category: Sumi, T]]
[[Category: Takahashi, K]]
[[Category: Isogai, Y]]
[[Category: Imamura, H]]