7dee - Revision history

OCA at 11:12, 14 June 2023

2023-06-14T11:12:40Z

← Older revision		Revision as of 11:12, 14 June 2023
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	====		==Structural Basis of the regulation of DISC Assembly by the interaction of c-FLIPs with Procaspase-8==
	<StructureSection load='7dee' size='340' side='right'caption='[[7dee]]' scene=''>		<StructureSection load='7dee' size='340' side='right'caption='[[7dee]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>		<table><tr><td colspan='2'>[[7dee]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DEE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dee OCA], [https://pdbe.org/7dee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dee RCSB], [https://www.ebi.ac.uk/pdbsum/7dee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dee ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dee OCA], [https://pdbe.org/7dee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dee RCSB], [https://www.ebi.ac.uk/pdbsum/7dee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dee ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/CFLAR_HUMAN CFLAR_HUMAN] Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.<ref>PMID:9880531</ref>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Z-disk~~]]		[[Category: Bai ZQ]]
			[[Category: Hu KF]]

OCA at 14:28, 3 November 2021

2021-11-03T14:28:34Z

← Older revision		Revision as of 14:28, 3 November 2021
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7dee ~~is ON HOLD until Paper Publication~~		====
			<StructureSection load='7dee' size='340' side='right'caption='[[7dee]]' scene=''>
	~~Authors~~: ~~Bai, Z~~.Q.~~, Hu, K~~.F.		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
	~~Description~~: ~~Structural Basis of the regulation of DISC Assembly by the interaction of c~~-~~FLIPs with Procaspase-8~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dee OCA], [https://pdbe.org/7dee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dee RCSB], [https://www.ebi.ac.uk/pdbsum/7dee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dee ProSAT]</span></td></tr>
	[[~~Category~~: ~~Unreleased Structures~~]]		</table>
	[[Category: ~~Bai, Z.Q~~]]		__TOC__
	[[Category: ~~Hu, K.F~~]]		</StructureSection>
			[[Category: Large Structures]]
			[[Category: Z-disk]]

OCA at 08:00, 18 November 2020

2020-11-18T08:00:55Z

← Older revision		Revision as of 08:00, 18 November 2020
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7dee is ON HOLD		The entry 7dee is ON HOLD until Paper Publication

	Authors: Bai, Z.Q., Hu, K.F.		Authors: Bai, Z.Q., Hu, K.F.

OCA: Protected "7dee" [edit=sysop:move=sysop]

2020-11-11T06:26:25Z

Protected "7dee" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:26, 11 November 2020
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7dee is ON HOLD Authors: Bai, Z.Q., Hu, K.F. Description: Structural Basis of the regulation of DISC Assembly by the interaction of c-FLIPs with Pr...

2020-11-11T06:26:24Z

New page: '''Unreleased structure''' The entry 7dee is ON HOLD Authors: Bai, Z.Q., Hu, K.F. Description: Structural Basis of the regulation of DISC Assembly by the interaction of c-FLIPs with Pr...

New page

'''Unreleased structure'''

The entry 7dee is ON HOLD

Authors: Bai, Z.Q., Hu, K.F.

Description: Structural Basis of the regulation of DISC Assembly by the interaction of c-FLIPs with Procaspase-8
[[Category: Unreleased Structures]]
[[Category: Bai, Z.Q]]
[[Category: Hu, K.F]]