7df2 - Revision history

OCA at 10:57, 23 October 2024

2024-10-23T10:57:20Z

← Older revision		Revision as of 10:57, 23 October 2024
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	<StructureSection load='7df2' size='340' side='right'caption='[[7df2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='7df2' size='340' side='right'caption='[[7df2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>~~[[7df2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ramva Ramva].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DF2 FirstGlance]. <br>		<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DF2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RvY_00338-1, RvY_00338.1, RvY_00338 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=947166 RAMVA])</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7df2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7df2 OCA], [https://pdbe.org/7df2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7df2 RCSB], [https://www.ebi.ac.uk/pdbsum/7df2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7df2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7df2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7df2 OCA], [https://pdbe.org/7df2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7df2 RCSB], [https://www.ebi.ac.uk/pdbsum/7df2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7df2 ProSAT]</span></td></tr>
	</table>		</table>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Ramva]]~~		[[Category: Fukuda Y]]
	[[Category: Fukuda, Y]]		[[Category: Inoue T]]
	[[Category: Inoue, T]]
	~~[[Category: C2 domain]]~~
	~~[[Category: Ca-binding protein]]~~
	~~[[Category: Metal binding protein]]~~
	~~[[Category: Tardigrade~~]]

OCA at 15:02, 3 March 2021

2021-03-03T15:02:29Z

← Older revision		Revision as of 15:02, 3 March 2021
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	==Crystal structure of a C2 domain protein from Ramazzottius varieornatus==		==Crystal structure of a C2 domain protein from Ramazzottius varieornatus==
	<StructureSection load='7df2' size='340' side='right'caption='[[7df2]]' scene=''>		<StructureSection load='7df2' size='340' side='right'caption='[[7df2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DF2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7DF2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[7df2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ramva Ramva]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DF2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=7df2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7df2 OCA], [~~http~~://pdbe.org/7df2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7df2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7df2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7df2 ProSAT]</span></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RvY_00338-1, RvY_00338.1, RvY_00338 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=947166 RAMVA])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7df2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7df2 OCA], [https://pdbe.org/7df2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7df2 RCSB], [https://www.ebi.ac.uk/pdbsum/7df2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7df2 ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Some tardigrades can survive extremely desiccated conditions through transition into a state called anhydrobiosis. Anhydrobiotic tardigrades have proteins unique to them and they are thought to be keys to the understanding of unusual desiccation resistance. In fact, previous transcriptome data show that several tardigrade-specific proteins are significantly upregulated under desiccated conditions. However, their physiological roles and chemical properties have been ambiguous because they show low or no similarity of amino acid sequences to proteins found in other organisms. Here, we report a crystal structure of one of such proteins. This protein shows a beta-sandwich structure composed of 8 beta-strands, three Ca(2+) -binding sites, and hydrophobic residues on Ca(2+) -binding (CBD) loops, which resemble characteristics of C2 domain proteins. We therefore conveniently describe this protein as tardigrade C2 domain protein (TC2P). Because the C2 domain functions as a Ca(2+) -mediated membrane docking module, which is related to signal transduction or membrane trafficking, TC2Ps may play a role in Ca(2+) -triggered phenomenon under desiccated situations. Our finding provides not only structural insights into a newly discovered desiccation-related protein family but also insights into the evolution and diversity of C2 domain proteins.

			Structural insights into a C2 domain protein specifically found in tardigrades.,Fukuda Y, Inoue T Protein Sci. 2020 Nov 23. doi: 10.1002/pro.4002. PMID:33226149<ref>PMID:33226149</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7df2" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Fukuda Y]]		[[Category: Ramva]]
	[[Category: Inoue T]]		[[Category: Fukuda, Y]]
			[[Category: Inoue, T]]
			[[Category: C2 domain]]
			[[Category: Ca-binding protein]]
			[[Category: Metal binding protein]]
			[[Category: Tardigrade]]

OCA at 06:41, 9 December 2020

2020-12-09T06:41:19Z

← Older revision		Revision as of 06:41, 9 December 2020
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7df2 is ~~ON HOLD~~		==Crystal structure of a C2 domain protein from Ramazzottius varieornatus==
			<StructureSection load='7df2' size='340' side='right'caption='[[7df2]]' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DF2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7DF2 FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7df2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7df2 OCA], [http://pdbe.org/7df2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7df2 RCSB], [http://www.ebi.ac.uk/pdbsum/7df2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7df2 ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Fukuda Y]]
			[[Category: Inoue T]]

OCA: Protected "7df2" [edit=sysop:move=sysop]

2020-11-11T06:28:16Z

Protected "7df2" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:28, 11 November 2020
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7df2 is ON HOLD Authors: Description: Category: Unreleased Structures

2020-11-11T06:28:15Z

New page: '''Unreleased structure''' The entry 7df2 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7df2 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]