7dxt - Revision history

OCA at 16:41, 29 November 2023

2023-11-29T16:41:31Z

← Older revision		Revision as of 16:41, 29 November 2023
Line 3:		Line 3:
	<StructureSection load='7dxt' size='340' side='right'caption='[[7dxt]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='7dxt' size='340' side='right'caption='[[7dxt]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7dxt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[7dxt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DXT FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dxt OCA], [https://pdbe.org/7dxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dxt RCSB], [https://www.ebi.ac.uk/pdbsum/7dxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dxt ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dxt OCA], [https://pdbe.org/7dxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dxt RCSB], [https://www.ebi.ac.uk/pdbsum/7dxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dxt ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Tagami, S~~]]		[[Category: Synthetic construct]]
	[[Category: ~~Yagi,~~ S]]		[[Category: Tagami S]]
	[[Category: ~~Chaperone]]~~		[[Category: Yagi S]]
	~~[[Category: Double psi beta barrel~~]]

OCA at 14:11, 17 November 2021

2021-11-17T14:11:55Z

← Older revision		Revision as of 14:11, 17 November 2021
Line 1:		Line 1:

	==Crystal structure of the chemically synthesized mk2h peptide homodimer==		==Crystal structure of the chemically synthesized mk2h peptide homodimer==
	<StructureSection load='7dxt' size='340' side='right'caption='[[7dxt]]' scene=''>		<StructureSection load='7dxt' size='340' side='right'caption='[[7dxt]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[7dxt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DXT FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dxt OCA], [https://pdbe.org/7dxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dxt RCSB], [https://www.ebi.ac.uk/pdbsum/7dxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dxt ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dxt OCA], [https://pdbe.org/7dxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dxt RCSB], [https://www.ebi.ac.uk/pdbsum/7dxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dxt ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The extant complex proteins must have evolved from ancient short and simple ancestors. The double-psi beta-barrel (DPBB) is one of the oldest protein folds and conserved in various fundamental enzymes, such as the core domain of RNA polymerase. Here, by reverse engineering a modern DPBB domain, we reconstructed its plausible evolutionary pathway started by "interlacing homodimerization" of a half-size peptide, followed by gene duplication and fusion. Furthermore, by simplifying the amino acid repertoire of the peptide, we successfully created the DPBB fold with only seven amino acid types (Ala, Asp, Glu, Gly, Lys, Arg, and Val), which can be coded by only GNN and ARR (R = A or G) codons in the modern translation system. Thus, the DPBB fold could have been materialized by the early translation system and genetic code.

			Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.,Yagi S, Padhi AK, Vucinic J, Barbe S, Schiex T, Nakagawa R, Simoncini D, Zhang KYJ, Tagami S J Am Chem Soc. 2021 Oct 6;143(39):15998-16006. doi: 10.1021/jacs.1c05367. Epub, 2021 Sep 24. PMID:34559526<ref>PMID:34559526</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7dxt" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Tagami S]]		[[Category: Tagami, S]]
	[[Category: Yagi S]]		[[Category: Yagi, S]]
			[[Category: Chaperone]]
			[[Category: Double psi beta barrel]]

OCA at 08:48, 29 September 2021

2021-09-29T08:48:44Z

← Older revision		Revision as of 08:48, 29 September 2021
Line 1:		Line 1:
	~~'''Unreleased structure'''~~

	~~The entry~~ 7dxt is ~~ON HOLD until Paper Publication~~		==Crystal structure of the chemically synthesized mk2h peptide homodimer==
			<StructureSection load='7dxt' size='340' side='right'caption='[[7dxt]]' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DXT FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dxt OCA], [https://pdbe.org/7dxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dxt RCSB], [https://www.ebi.ac.uk/pdbsum/7dxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dxt ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Tagami S]]
			[[Category: Yagi S]]

OCA at 09:07, 10 February 2021

2021-02-10T09:07:40Z

← Older revision		Revision as of 09:07, 10 February 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7dxt is ON HOLD		The entry 7dxt is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "7dxt" [edit=sysop:move=sysop]

2021-01-27T06:41:38Z

Protected "7dxt" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:41, 27 January 2021
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7dxt is ON HOLD Authors: Description: Category: Unreleased Structures

2021-01-27T06:41:37Z

New page: '''Unreleased structure''' The entry 7dxt is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 7dxt is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]