7evd - Revision history

OCA at 17:04, 29 November 2023

2023-11-29T17:04:58Z

← Older revision		Revision as of 17:04, 29 November 2023
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	<StructureSection load='7evd' size='340' side='right'caption='[[7evd]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='7evd' size='340' side='right'caption='[[7evd]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7evd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EVD FirstGlance]. <br>		<table><tr><td colspan='2'>[[7evd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candidatus_Odinarchaeota_archaeon_LCB_4 Candidatus Odinarchaeota archaeon LCB_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EVD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7evb\|7evb]], [[7evc\|7evc]]</div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7evd OCA], [https://pdbe.org/7evd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7evd RCSB], [https://www.ebi.ac.uk/pdbsum/7evd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7evd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7evd OCA], [https://pdbe.org/7evd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7evd RCSB], [https://www.ebi.ac.uk/pdbsum/7evd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7evd ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/A0A1Q9N9N5_ODILC A0A1Q9N9N5_ODILC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Candidatus Odinarchaeota archaeon LCB_4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Akil, C]]		[[Category: Akil C]]
	[[Category: Robinson~~, R C~~]]		[[Category: Robinson RC]]
	[[Category: Tran~~, L T]]~~		[[Category: Tran LT]]
	~~[[Category: Asgard]]~~
	~~[[Category: Filament]]~~
	~~[[Category: Gtp]]~~
	~~[[Category: Structural protein]]~~
	~~[[Category: Tubulin~~]]

OCA at 05:16, 15 June 2022

2022-06-15T05:16:43Z

← Older revision		Revision as of 05:16, 15 June 2022
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	==Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 53% GTP/47% and 2 Na+==		==Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 53% GTP/47% and 2 Na+==
	<StructureSection load='7evd' size='340' side='right'caption='[[7evd]]' scene=''>		<StructureSection load='7evd' size='340' side='right'caption='[[7evd]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EVD FirstGlance]. <br>		<table><tr><td colspan='2'>[[7evd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EVD FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7evd OCA], [https://pdbe.org/7evd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7evd RCSB], [https://www.ebi.ac.uk/pdbsum/7evd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7evd ProSAT]</span></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7evb\|7evb]], [[7evc\|7evc]]</div></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7evd OCA], [https://pdbe.org/7evd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7evd RCSB], [https://www.ebi.ac.uk/pdbsum/7evd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7evd ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Tubulins are critical for the internal organization of eukaryotic cells, and understanding their emergence is an important question in eukaryogenesis. Asgard archaea are the closest known prokaryotic relatives to eukaryotes. Here, we elucidated the apo and nucleotide-bound x-ray structures of an Asgard tubulin from hydrothermal living Odinarchaeota (OdinTubulin). The guanosine 5'-triphosphate (GTP)-bound structure resembles a microtubule protofilament, with GTP bound between subunits, coordinating the "+" end subunit through a network of water molecules and unexpectedly by two cations. A water molecule is located suitable for GTP hydrolysis. Time course crystallography and electron microscopy revealed conformational changes on GTP hydrolysis. OdinTubulin forms tubules at high temperatures, with short curved protofilaments coiling around the tubule circumference, more similar to FtsZ, rather than running parallel to its length, as in microtubules. Thus, OdinTubulin represents an evolutionary stage intermediate between prokaryotic FtsZ and eukaryotic microtubule-forming tubulins.

			Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution.,Akil C, Ali S, Tran LT, Gaillard J, Li W, Hayashida K, Hirose M, Kato T, Oshima A, Fujishima K, Blanchoin L, Narita A, Robinson RC Sci Adv. 2022 Mar 25;8(12):eabm2225. doi: 10.1126/sciadv.abm2225. Epub 2022 Mar, 25. PMID:35333570<ref>PMID:35333570</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 7evd" style="background-color:#fffaf0;"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Akil C]]		[[Category: Akil, C]]
	[[Category: Robinson RC]]		[[Category: Robinson, R C]]
	[[Category: Tran LT]]		[[Category: Tran, L T]]
			[[Category: Asgard]]
			[[Category: Filament]]
			[[Category: Gtp]]
			[[Category: Structural protein]]
			[[Category: Tubulin]]

OCA at 11:16, 23 March 2022

2022-03-23T11:16:29Z

← Older revision		Revision as of 11:16, 23 March 2022
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7evd is ~~ON HOLD until Paper Publication~~		==Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 53% GTP/47% and 2 Na+==
			<StructureSection load='7evd' size='340' side='right'caption='[[7evd]]' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EVD FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7evd OCA], [https://pdbe.org/7evd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7evd RCSB], [https://www.ebi.ac.uk/pdbsum/7evd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7evd ProSAT]</span></td></tr>
	[[Category: ~~Unreleased Structures~~]]		</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Akil C]]
			[[Category: Robinson RC]]
			[[Category: Tran LT]]

OCA at 08:38, 7 July 2021

2021-07-07T08:38:13Z

← Older revision		Revision as of 08:38, 7 July 2021
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7evd is ON HOLD		The entry 7evd is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 06:02, 25 June 2021

2021-06-25T06:02:54Z

← Older revision		Revision as of 06:02, 25 June 2021
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	The entry 7evd is ON HOLD		The entry 7evd is ON HOLD

	Authors: ~~Robinson, R.C., Akil, C., Tran, L.T.~~		Authors:

	Description: ~~Odinarchaeota tubulin H392D mutant bound to 53% GTP/47% GDP~~		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Akil, C]]~~
	~~[[Category: Robinson, R.C]]~~
	~~[[Category: Tran, L.T]]~~

OCA: Protected "7evd" [edit=sysop:move=sysop]

2021-05-26T07:52:50Z

Protected "7evd" [edit=sysop:move=sysop]

← Older revision	Revision as of 07:52, 26 May 2021
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7evd is ON HOLD Authors: Robinson, R.C., Akil, C., Tran, L.T. Description: Odinarchaeota tubulin H392D mutant bound to 53% GTP/47% GDP [[Category: ...

2021-05-26T07:52:49Z

New page: '''Unreleased structure''' The entry 7evd is ON HOLD Authors: Robinson, R.C., Akil, C., Tran, L.T. Description: Odinarchaeota tubulin H392D mutant bound to 53% GTP/47% GDP [[Category: ...

New page

'''Unreleased structure'''

The entry 7evd is ON HOLD

Authors: Robinson, R.C., Akil, C., Tran, L.T.

Description: Odinarchaeota tubulin H392D mutant bound to 53% GTP/47% GDP
[[Category: Unreleased Structures]]
[[Category: Akil, C]]
[[Category: Robinson, R.C]]
[[Category: Tran, L.T]]