7sty - Revision history

OCA at 16:54, 18 October 2023

2023-10-18T16:54:38Z

← Older revision		Revision as of 16:54, 18 October 2023
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	==Crystal structure of human CORO1C==		==Crystal structure of human CORO1C==
	<StructureSection load='7sty' size='340' side='right'caption='[[7sty]]' scene=''>		<StructureSection load='7sty' size='340' side='right'caption='[[7sty]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7STY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7STY FirstGlance]. <br>		<table><tr><td colspan='2'>[[7sty]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7STY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7STY FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sty OCA], [https://pdbe.org/7sty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sty RCSB], [https://www.ebi.ac.uk/pdbsum/7sty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sty ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sty OCA], [https://pdbe.org/7sty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sty RCSB], [https://www.ebi.ac.uk/pdbsum/7sty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sty ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/COR1C_HUMAN COR1C_HUMAN] Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed:25074804, PubMed:25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed:25074804, PubMed:25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (By similarity). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed:30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed:30220460). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (By similarity). Required for normal distribution of mitochondria within cells (By similarity).[UniProtKB:Q9WUM4]<ref>PMID:25074804</ref> <ref>PMID:25925950</ref> <ref>PMID:30220460</ref> <ref>PMID:34106209</ref> Involved in myogenic differentiation.<ref>PMID:19651142</ref>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arrowsmith CH]]		[[Category: Arrowsmith CH]]

OCA at 06:22, 1 December 2021

2021-12-01T06:22:58Z

← Older revision		Revision as of 06:22, 1 December 2021
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7sty is ~~ON HOLD~~		==Crystal structure of human CORO1C==
			<StructureSection load='7sty' size='340' side='right'caption='[[7sty]]' scene=''>
	~~Authors~~: ~~Dong~~, A.~~, Zeng, H~~.~~, Hutchinson, A~~., ~~Seitova, A~~., ~~Loppnau, P~~.~~, Arrowsmith, C~~.H., ~~Edwards, A~~.M., ~~Halabelian, L~~.~~, Structural Genomics Consortium (SGC)~~		== Structural highlights ==
			<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7STY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7STY FirstGlance]. <br>
	~~Description: Crystal structure of human CORO1C~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sty OCA], [https://pdbe.org/7sty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sty RCSB], [https://www.ebi.ac.uk/pdbsum/7sty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sty ProSAT]</span></td></tr>
	[[Category: ~~Unreleased~~ Structures]]		</table>
	[[Category: ~~Loppnau, P~~]]		__TOC__
	[[Category: ~~Hutchinson,~~ A]]		</StructureSection>
	[[Category: Edwards~~, A.M~~]]		[[Category: Large Structures]]
	[[Category: ~~Arrowsmith, C.H~~]]		[[Category: Arrowsmith CH]]
	[[Category: ~~Seitova,~~ A]]		[[Category: Dong A]]
	[[Category: ~~Dong, A~~]]		[[Category: Edwards AM]]
	[[Category: ~~Structural Genomics Consortium (Sgc)]]~~		[[Category: Halabelian L]]
	~~[[Category: Halabelian, L~~]]		[[Category: Hutchinson A]]
	[[Category: Zeng, H]]		[[Category: Loppnau P]]
			[[Category: Seitova A]]
			[[Category: Zeng H]]

OCA: Protected "7sty" [edit=sysop:move=sysop]

2021-11-24T10:59:30Z

Protected "7sty" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:59, 24 November 2021
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7sty is ON HOLD Authors: Dong, A., Zeng, H., Hutchinson, A., Seitova, A., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural G...

2021-11-24T10:59:29Z

New page: '''Unreleased structure''' The entry 7sty is ON HOLD Authors: Dong, A., Zeng, H., Hutchinson, A., Seitova, A., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural G...

New page

'''Unreleased structure'''

The entry 7sty is ON HOLD

Authors: Dong, A., Zeng, H., Hutchinson, A., Seitova, A., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)

Description: Crystal structure of human CORO1C
[[Category: Unreleased Structures]]
[[Category: Loppnau, P]]
[[Category: Hutchinson, A]]
[[Category: Edwards, A.M]]
[[Category: Arrowsmith, C.H]]
[[Category: Seitova, A]]
[[Category: Dong, A]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Halabelian, L]]
[[Category: Zeng, H]]