7vsf - Revision history

OCA at 11:08, 2 August 2023

2023-08-02T11:08:31Z

← Older revision		Revision as of 11:08, 2 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7vsf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[7vsf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VSF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7UM:3-methyl-7-propyl-purine-2,6-dione'>7UM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7UM:3-methyl-7-propyl-purine-2,6-dione'>7UM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vsf OCA], [https://pdbe.org/7vsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vsf RCSB], [https://www.ebi.ac.uk/pdbsum/7vsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vsf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vsf OCA], [https://pdbe.org/7vsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vsf RCSB], [https://www.ebi.ac.uk/pdbsum/7vsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vsf ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:16, 1 February 2023

2023-02-01T11:16:55Z

← Older revision		Revision as of 11:16, 1 February 2023
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7vsf is ~~ON HOLD until 2024~~-~~01-26~~		==crystal structure of BRD2-BD1 in complex with purine derivative==
			<StructureSection load='7vsf' size='340' side='right'caption='[[7vsf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	~~Authors~~: ~~Padmanabhan~~, B., ~~Arole~~, A., ~~Deshmukh~~, P., ~~Ashok~~, S., ~~Mathur, S~~.		== Structural highlights ==
			<table><tr><td colspan='2'>[[7vsf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VSF FirstGlance]. <br>
	~~Description~~: ~~crystal structure~~ of ~~BRD2-BD1~~ in ~~complex with purine derivative~~		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7UM:3-methyl-7-propyl-purine-2,6-dione'>7UM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vsf OCA], [https://pdbe.org/7vsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vsf RCSB], [https://www.ebi.ac.uk/pdbsum/7vsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vsf ProSAT]</span></td></tr>
	[[Category: ~~Mathur, S~~]]		</table>
	[[Category: ~~Padmanabhan, B~~]]		== Function ==
	[[Category: Ashok, S]]		[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
	[[Category: Deshmukh, P]]		== References ==
	[[Category: ~~Arole, A~~]]		<references/>
			__TOC__
			</StructureSection>
			[[Category: Homo sapiens]]
			[[Category: Large Structures]]
			[[Category: Arole A]]
			[[Category: Ashok S]]
			[[Category: Deshmukh P]]
			[[Category: Mathur S]]
			[[Category: Padmanabhan B]]

OCA at 16:30, 19 October 2022

2022-10-19T16:30:44Z

← Older revision		Revision as of 16:30, 19 October 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7vsf is ON HOLD until ~~2023~~-10-26		The entry 7vsf is ON HOLD until 2024-01-26

	Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.		Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.
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	Description: crystal structure of BRD2-BD1 in complex with purine derivative		Description: crystal structure of BRD2-BD1 in complex with purine derivative
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Mathur, S]]
	[[Category: Padmanabhan, B]]		[[Category: Padmanabhan, B]]
	[[Category: Ashok, S]]		[[Category: Ashok, S]]
			[[Category: Deshmukh, P]]
	[[Category: Arole, A]]		[[Category: Arole, A]]
	~~[[Category: Mathur, S]]~~
	~~[[Category: Deshmukh, P]]~~

OCA at 06:51, 22 June 2022

2022-06-22T06:51:21Z

← Older revision		Revision as of 06:51, 22 June 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7vsf is ON HOLD until ~~Oct~~ 26 ~~2023~~		The entry 7vsf is ON HOLD until 2023-10-26

	Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.		Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.

OCA at 12:28, 29 December 2021

2021-12-29T12:28:44Z

← Older revision		Revision as of 12:28, 29 December 2021
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7vsf is ON HOLD		The entry 7vsf is ON HOLD until Oct 26 2023

	Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.		Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.
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	Description: crystal structure of BRD2-BD1 in complex with purine derivative		Description: crystal structure of BRD2-BD1 in complex with purine derivative
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Mathur, S]]~~
	[[Category: Padmanabhan, B]]		[[Category: Padmanabhan, B]]
	[[Category: Ashok, S]]		[[Category: Ashok, S]]
			[[Category: Arole, A]]
			[[Category: Mathur, S]]
	[[Category: Deshmukh, P]]		[[Category: Deshmukh, P]]
	~~[[Category: Arole, A]]~~

OCA: Protected "7vsf" [edit=sysop:move=sysop]

2021-11-03T13:02:35Z

Protected "7vsf" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:02, 3 November 2021
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7vsf is ON HOLD Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S. Description: crystal structure of BRD2-BD1 in complex with...

2021-11-03T13:02:34Z

New page: '''Unreleased structure''' The entry 7vsf is ON HOLD Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S. Description: crystal structure of BRD2-BD1 in complex with...

New page

'''Unreleased structure'''

The entry 7vsf is ON HOLD

Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.

Description: crystal structure of BRD2-BD1 in complex with purine derivative
[[Category: Unreleased Structures]]
[[Category: Mathur, S]]
[[Category: Padmanabhan, B]]
[[Category: Ashok, S]]
[[Category: Deshmukh, P]]
[[Category: Arole, A]]