7yth - Revision history

OCA at 10:13, 16 August 2023

2023-08-16T10:13:59Z

← Older revision		Revision as of 10:13, 16 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[7yth]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_flagelliforme_CCNUN1 Nostoc flagelliforme CCNUN1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YTH FirstGlance]. <br>		<table><tr><td colspan='2'>[[7yth]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_flagelliforme_CCNUN1 Nostoc flagelliforme CCNUN1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YTH FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yth OCA], [https://pdbe.org/7yth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yth RCSB], [https://www.ebi.ac.uk/pdbsum/7yth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yth ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.93Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yth OCA], [https://pdbe.org/7yth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yth RCSB], [https://www.ebi.ac.uk/pdbsum/7yth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yth ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 09:36, 21 June 2023

2023-06-21T09:36:07Z

← Older revision		Revision as of 09:36, 21 June 2023
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	~~'''Unreleased structure'''~~

	~~The entry~~ 7yth is ~~ON HOLD until Paper~~ Publication		==Structure of OCPx1 from Nostoc flagelliforme CCNUN1==
			<StructureSection load='7yth' size='340' side='right'caption='[[7yth]], [[Resolution\|resolution]] 1.93Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[7yth]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_flagelliforme_CCNUN1 Nostoc flagelliforme CCNUN1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YTH FirstGlance]. <br>
			</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yth OCA], [https://pdbe.org/7yth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yth RCSB], [https://www.ebi.ac.uk/pdbsum/7yth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yth ProSAT]</span></td></tr>
			</table>
			== Function ==
			[https://www.uniprot.org/uniprot/A0A2K8SJT8_9NOSO A0A2K8SJT8_9NOSO]
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Orange carotenoid protein (OCP) is a photoactive protein that participates in the photoprotection of cyanobacteria. There are two full-length OCP proteins, four N-terminal paralogs (helical carotenoid protein, HCP), and one C-terminal domain-like carotenoid protein (CCP) found in Nostoc flagelliforme, a desert cyanobacterium. All HCPs (HCP1-3 and HCP6) from N. flagelliforme demonstrated their excellent singlet oxygen quenching activities, in which HCP2 was the strongest singlet oxygen quencher compared with others. Two OCPs, OCPx1 and OCPx2, were not involved in singlet oxygen scavenging; instead, they functioned as phycobilisome fluorescence quenchers. The fast-acting OCPx1 showed more effective photoactivation and stronger phycobilisome fluorescence quenching compared to OCPx2, which behaved differently from all reported OCP paralogs. The resolved crystal structure and mutant analysis revealed that Trp111 and Met125 play essential roles in OCPx2, which is dominant and long-acting. The resolved crystal structure of OCPx2 is maintained in a monomer state and showed more flexible regulation in energy quenching activities compared with the packed oligomer of OCPx1. The recombinant apo-CCP obtained the carotenoid pigment from holo-HCPs and holo-OCPx1 of N. flagelliforme. No such carotenoid transferring processes were observed between apo-CCP and holo-OCPx2. The close phylogenetic relationship of OCP paralogs from subaerial Nostoc species indicates an adaptive evolution toward development of photoprotection: protecting cellular metabolism against singlet oxygen damage using HCPs and against excess energy captured by active phycobilisomes using two different working modes of OCPx.

	~~Authors:~~ Yang~~, Y.W.~~, Liu, K., ~~Chen~~, ~~S.Z.~~, Chen, M., Qiu~~, B~~.S.		Functional specialization of expanded orange carotenoid protein paralogs in subaerial Nostoc species.,Yang YW, Liu K, Huang D, Yu C, Chen SZ, Chen M, Qiu BS Plant Physiol. 2023 Apr 18:kiad234. doi: 10.1093/plphys/kiad234. PMID:37070859<ref>PMID:37070859</ref>

	~~Description~~: ~~Structure of OCPx1 from Nostoc flagelliforme CCNUN1~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	[[Category: ~~Unreleased~~ Structures]]		</div>
	[[Category: ~~Yang, Y.W~~]]		<div class="pdbe-citations 7yth" style="background-color:#fffaf0;"></div>
	[[Category: Chen, M]]		== References ==
	[[Category: ~~Qiu, B.S~~]]		<references/>
	[[Category: ~~Chen, S.Z~~]]		__TOC__
	[[Category: ~~Liu, K~~]]		</StructureSection>
			[[Category: Large Structures]]
			[[Category: Nostoc flagelliforme CCNUN1]]
			[[Category: Chen M]]
			[[Category: Chen SZ]]
			[[Category: Liu K]]
			[[Category: Qiu BS]]
			[[Category: Yang YW]]

OCA at 15:21, 7 September 2022

2022-09-07T15:21:23Z

← Older revision		Revision as of 15:21, 7 September 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 7yth is ON HOLD		The entry 7yth is ON HOLD until Paper Publication

	Authors: Yang, Y.W., Liu, K., Chen, S.Z., Chen, M., Qiu, B.S.		Authors: Yang, Y.W., Liu, K., Chen, S.Z., Chen, M., Qiu, B.S.
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	Description: Structure of OCPx1 from Nostoc flagelliforme CCNUN1		Description: Structure of OCPx1 from Nostoc flagelliforme CCNUN1
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Qiu, B.S]]~~
	~~[[Category: Liu, K]]~~
	[[Category: Yang, Y.W]]		[[Category: Yang, Y.W]]
	[[Category: Chen, M]]		[[Category: Chen, M]]
			[[Category: Qiu, B.S]]
	[[Category: Chen, S.Z]]		[[Category: Chen, S.Z]]
			[[Category: Liu, K]]

OCA: Protected "7yth" [edit=sysop:move=sysop]

2022-08-25T03:37:17Z

Protected "7yth" [edit=sysop:move=sysop]

← Older revision	Revision as of 03:37, 25 August 2022
(No difference)

OCA: New page: '''Unreleased structure''' The entry 7yth is ON HOLD Authors: Yang, Y.W., Liu, K., Chen, S.Z., Chen, M., Qiu, B.S. Description: Structure of OCPx1 from Nostoc flagelliforme CCNUN1 [[Ca...

2022-08-25T03:37:16Z

New page: '''Unreleased structure''' The entry 7yth is ON HOLD Authors: Yang, Y.W., Liu, K., Chen, S.Z., Chen, M., Qiu, B.S. Description: Structure of OCPx1 from Nostoc flagelliforme CCNUN1 [[Ca...

New page

'''Unreleased structure'''

The entry 7yth is ON HOLD

Authors: Yang, Y.W., Liu, K., Chen, S.Z., Chen, M., Qiu, B.S.

Description: Structure of OCPx1 from Nostoc flagelliforme CCNUN1
[[Category: Unreleased Structures]]
[[Category: Qiu, B.S]]
[[Category: Liu, K]]
[[Category: Yang, Y.W]]
[[Category: Chen, M]]
[[Category: Chen, S.Z]]