8a22 - Revision history

OCA at 09:25, 17 October 2024

2024-10-17T09:25:49Z

← Older revision		Revision as of 09:25, 17 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8a22]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Polytomella_magna Polytomella magna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A22 FirstGlance]. <br>		<table><tr><td colspan='2'>[[8a22]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Polytomella_magna Polytomella magna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A22 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 2.91Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a22 OCA], [https://pdbe.org/8a22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a22 RCSB], [https://www.ebi.ac.uk/pdbsum/8a22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a22 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a22 OCA], [https://pdbe.org/8a22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a22 RCSB], [https://www.ebi.ac.uk/pdbsum/8a22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a22 ProSAT]</span></td></tr>
	</table>		</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Mitoribosomes of green algae display a great structural divergence from their tracheophyte relatives, with fragmentation of both rRNA and proteins as a defining feature. Here, we report a 2.9 A resolution structure of the mitoribosome from the alga Polytomella magna harbouring a reduced rRNA split into 13 fragments. We found that the rRNA contains a non-canonical reduced form of the 5S, as well as a permutation of the LSU domain I. The mt-5S rRNA is stabilised by mL40 that is also found in mitoribosomes lacking the 5S, which suggests an evolutionary pathway. Through comparison to other ribosomes with fragmented rRNAs, we observe that the pattern is shared across large evolutionary distances, and between cellular compartments, indicating an evolutionary convergence and supporting the concept of a primordial fragmented ribosome. On the protein level, eleven peripherally associated HEAT-repeat proteins are involved in the binding of 3' rRNA termini, and the structure features a prominent pseudo-trimer of one of them (mL116). Finally, in the exit tunnel, mL128 constricts the tunnel width of the vestibular area, and mL105, a homolog of a membrane targeting component mediates contacts with an inner membrane bound insertase. Together, the structural analysis provides insight into the evolution of the ribosomal machinery in mitochondria.

			Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.,Tobiasson V, Berzina I, Amunts A Nat Commun. 2022 Oct 17;13(1):6132. doi: 10.1038/s41467-022-33582-5. PMID:36253367<ref>PMID:36253367</ref>

			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
			<div class="pdbe-citations 8a22" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Ribosome 3D structures\|Ribosome 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 20:12, 16 November 2022

2022-11-16T20:12:19Z

← Older revision		Revision as of 20:12, 16 November 2022
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	~~'''Unreleased structure'''~~

	~~The entry~~ 8a22 is ~~ON HOLD until Paper Publication~~		==Structure of the mitochondrial ribosome from Polytomella magna==
			<StructureSection load='8a22' size='340' side='right'caption='[[8a22]], [[Resolution\|resolution]] 2.91Å' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>[[8a22]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Polytomella_magna Polytomella magna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A22 FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a22 OCA], [https://pdbe.org/8a22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a22 RCSB], [https://www.ebi.ac.uk/pdbsum/8a22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a22 ProSAT]</span></td></tr>
			</table>
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Polytomella magna]]
			[[Category: Amunts A]]
			[[Category: Berzina I]]
			[[Category: Tobiasson V]]

OCA at 16:34, 19 October 2022

2022-10-19T16:34:46Z

← Older revision		Revision as of 16:34, 19 October 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 8a22 is ON HOLD		The entry 8a22 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8a22" [edit=sysop:move=sysop]

2022-06-08T04:24:06Z

Protected "8a22" [edit=sysop:move=sysop]

← Older revision	Revision as of 04:24, 8 June 2022
(No difference)

OCA: New page: '''Unreleased structure''' The entry 8a22 is ON HOLD Authors: Description: Category: Unreleased Structures

2022-06-08T04:24:05Z

New page: '''Unreleased structure''' The entry 8a22 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8a22 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]